本文選題：HIV/AIDS　切入點(diǎn)：艾滋病抗病毒治療　出處：《濟(jì)南大學(xué)》2017年碩士論文

【摘要】：目的本研究通過(guò)分析濟(jì)南市接受抗病毒治療的艾滋病患者的依從性教育知識(shí)知曉率、藥物服用情況、換藥影響因素、性行為相關(guān)情況、社會(huì)支持狀況、婚育計(jì)劃,合并感染及機(jī)會(huì)性感染情況,為今后開(kāi)展艾滋病抗病毒治療工作提供參考依據(jù)。方法本文采用方便抽樣的方法,于2016年6月至10月在濟(jì)南市傳染病醫(yī)院對(duì)目前接受艾滋病抗病毒治療人群在知情同意的前提下進(jìn)行問(wèn)卷調(diào)查并對(duì)其中的部分研究對(duì)象進(jìn)行面對(duì)面訪談。使用Epi Data 3.1建立數(shù)據(jù)庫(kù)并進(jìn)行雙錄入并核對(duì),采用SPSS 21.0統(tǒng)計(jì)軟件進(jìn)行數(shù)據(jù)的統(tǒng)計(jì)分析,檢驗(yàn)水準(zhǔn)取ɑ=0.05。將訪談錄音資料逐句整理成文字,并對(duì)資料進(jìn)行歸類分析并得出結(jié)論。結(jié)果1.截至2016年6月在濟(jì)南市傳染病醫(yī)院接受抗病毒治療的艾滋病患者共857人,本次共調(diào)查316名接受抗病毒治療的艾滋病患者,其中有12人在宣讀知情同意書內(nèi)容后拒絕參與本次調(diào)查,共收回有效問(wèn)卷304份。2.濟(jì)南市接受抗病毒治療的艾滋病患者以男性為主,占97.4%(296/304),女性占2.6%(8/304),平均年齡為(31.98±8.15)歲,傳播途徑以同性傳播為主,占93.4%(284/304),異性傳播、受血或血制品感染、靜脈吸毒感染的分別占3.9%(12/304)、1.0%(3/304)、0.7%(2/304)。3.近一個(gè)月按時(shí)服藥的占96.7%(294/304),每月服藥天數(shù)中位數(shù)是30天;未漏服過(guò)艾滋病抗病毒治療藥物的占79.9%(243/304)。15.8%(48/304)的艾滋病患者更換過(guò)藥物;更換藥物的原因是藥物副反應(yīng)嚴(yán)重41.7%(20/48),耐藥35.4%(17/48),因免疫重建不良/失敗而醫(yī)生建議換藥22.9%(11/48)。4.艾滋病抗病毒治療后,80.6%(245/304)的艾滋病患者性伴個(gè)數(shù)減少,18.4%(56/304)性伴個(gè)數(shù)沒(méi)變化,1.0%(3/304)性伴個(gè)數(shù)增加了。性生活頻率方面,86.2%(262/304)的艾滋病患者抗病毒治療后性生活頻率下降,12.5%(38/304)的性生活頻率沒(méi)有發(fā)生改變,1.3%(4/304)的性生活頻率增加。最近一次性行為時(shí)全程正確使用安全套的占82.9%(252/304)。5.未來(lái)有結(jié)婚打算的占24.7%(54/219);因父母要求而未來(lái)有結(jié)婚計(jì)劃的占53.7%(29/54),自己希望結(jié)婚的占46.3%(25/54);未來(lái)有生育子女計(jì)劃的占30.9%(94/304);未來(lái)有生育子女計(jì)劃的艾滋病患者中,70.2%(66/94)是由于自己想要,26.6%(25/94)是由于父母要求,3.2%(3/94)是由于配偶想要。6.近一年內(nèi)未患肺結(jié)核的艾滋病患者占95.7%(291/304)。近三個(gè)月內(nèi)出現(xiàn)機(jī)會(huì)性感染癥狀及體征的艾滋病患者占18.1%(55/304),主要是皮膚損害的有38.2%(21/55)、鵝口瘡的有23.6%(13/55)、持續(xù)腹瀉(1個(gè)月)的有21.8%(12/55)、持續(xù)或間斷發(fā)熱(38oC,1個(gè)月)的有20.0%(11/55)等癥狀和體征。結(jié)論1.目前濟(jì)南艾滋病患者抗病毒治療管理工作采用定點(diǎn)醫(yī)院為主導(dǎo)的模式,效果良好,主要表現(xiàn)為艾滋病患者服藥依從性良好、漏服率低、換藥率低、合并感染和機(jī)會(huì)性感染率低。2.濟(jì)南市接受抗病毒治療的人群以男男同性性行為人群為主,這與濟(jì)南市艾滋病流行特征相符。正在接受抗病毒治療的艾滋病患者有結(jié)婚和生育的意愿或計(jì)劃,提示下一步應(yīng)加強(qiáng)艾滋病二代傳播的預(yù)防與控制工作。3.艾滋病患者接受抗病毒治療后雖然性行為有所變化,但仍需持續(xù)加強(qiáng)該人群的行為干預(yù)工作,尤其是安全套推廣及正確使用,控制艾滋病的進(jìn)一步傳播。4.濟(jì)南市正在接受抗病毒治療的艾滋病患者有較強(qiáng)的社會(huì)支持需求和心理需求,今后應(yīng)繼續(xù)發(fā)揮社會(huì)組織的獨(dú)特優(yōu)勢(shì),為艾滋病患者提供心理關(guān)懷和社會(huì)救助等服務(wù)。
[Abstract]:The purpose of this study is through the analysis of Ji'nan receiving antiretroviral treatment of AIDS patients compliance education knowledge awareness, medication compliance, dressing factors, related to sexual behavior, social support, marriage plans, infection and opportunistic infection, to provide reference for the future development of AIDS antiviral treatment work. By convenient sampling method in this paper methods from June 2016 to October in Jinan Infectious Disease Hospital of currently receiving antiretroviral therapy groups conducted a questionnaire survey on the premise of informed consent and face-to-face interviews on the part of the research object. Using Epi Data 3.1 database and the establishment of double entry and check, statistical data analysis was performed using SPSS 21 statistical software testing standard. =0.05. will interview records by sorting into text, and the data were classified and analyzed Results and conclusion. As of June 2016 1. at the Jinan Infectious Disease Hospital receiving antiretroviral treatment of AIDS patients with a total of 857 people, the total 316 participants receiving antiretroviral treatment of AIDS patients, 12 of them refused to participate in the investigation and read the informed consent after the contents of 304 valid questionnaires were collected in Ji'nan.2. receiving antiretroviral treatment of AIDS patients were predominantly male, accounting for 97.4% (296/304), women accounted for 2.6% (8/304), mean age (31.98 + 8.15) years old, homosexual transmission ways to spread mainly accounted for 93.4% (284/304), heterosexual transmission, receiving blood or blood products infected, intravenous drug users accounted for 3.9% (12/304), 1% (3/304), 0.7% (2/304).3. nearly a month of medication accounted for 96.7% (294/304), the median duration of medication per month is 30 days; not missed drug antiretroviral therapy for HIV / AIDS accounted for 79.9% (243/304).15.8% (48/304) of AIDS patients The replacement of drugs; drug replacement is the cause of serious adverse drug reactions (20/48), 41.7% (17/48), because of drug resistance of 35.4% adverse immune reconstitution / failure and doctors recommend dressing 22.9% (11/48).4. AIDS antiviral treatment, 80.6% (245/304) of AIDS patients to reduce the number of sexual partners, 18.4% (56/304) with a the number did not change, 1% (3/304). The number of sexual partners increased sexual frequency, 86.2% (262/304) of AIDS patients receiving antiretroviral treatment after sexual life frequency decreased 12.5% (38/304) the frequency of sexual life has not changed, 1.3% (4/ 304) the frequency of sexual life. Recent sexual full right the use of condoms accounted for 82.9% (252/304).5. future plans to marry accounted for 24.7% (54/219); his parents and future marriage plans accounted for 53.7% (29/54), their hope of marriage accounted for 46.3% (25/ 54); the future plan of children accounted for 30.9% (94/304); future Have the children plan of AIDS patients, 70.2% (66/94) as you want, 26.6% (25/94) is due to parents, 3.2% (3/94) to.6. not is because the spouse suffered from tuberculosis in nearly a year of AIDS patients accounted for 95.7% (291/304). The past three months for infection symptoms and the signs of AIDS patients accounted for 18.1% (55/304), is mainly the skin damage is 38.2% (21/55), thrush 23.6% (13/55), persistent diarrhea (1 months) was 21.8% (12/55), persistent or intermittent fever (38oC 1 months) was 20% (11 /55). The symptoms and signs. The conclusion of the 1. current antiviral therapy management of AIDS patients in Ji'nan hospitals by the leading model, the effect is good, mainly for AIDS medication compliance, missed rate low, dressing rate is low, rate of infection and antiviral treatment of opportunistic infections in low.2. Ji'nan city crowd to male Male homosexual crowd, which is consistent with the epidemic characteristics of AIDS in Ji'nan city. Are receiving antiretroviral treatment of AIDS patients have marriage and childbearing intention or plan, suggesting that the next step should be to strengthen AIDS prevention and control the spread of the two generation of.3. AIDS patients receiving antiretroviral treatment after sex change, but still need to continue strengthen the work of behavioral intervention in this population, especially the promotion of condom use and proper use, control the further spread of AIDS in Ji'nan city.4. are receiving antiretroviral treatment of AIDS patients have a strong social support and psychological needs, the future should continue to play a unique advantage of the social organization, psychological care and social assistance services for AIDS patients.

【學(xué)位授予單位】：濟(jì)南大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R512.91

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