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模式識(shí)別受體在HBV感染過程中的作用研究進(jìn)展

發(fā)布時(shí)間:2018-03-25 15:03

  本文選題:乙型肝炎病毒 切入點(diǎn):模式識(shí)別受體 出處:《實(shí)用肝臟病雜志》2016年06期


【摘要】:乙型肝炎病毒感染后�?蓪�(dǎo)致慢性乙型肝炎。機(jī)體模式識(shí)別受體(PRRs)作為一類重要的識(shí)別分子,在病毒感染早期可識(shí)別病原體并誘導(dǎo)抗病毒免疫應(yīng)答。本文闡述了PRRs的定義、種類和信號(hào)通路,將其分為Toll樣受體家族和Toll非依賴性模式識(shí)別受體家族,介紹了其與乙型肝炎病毒感染之間的關(guān)系。
[Abstract]:Hepatitis B virus infection often leads to chronic hepatitis B. as an important recognition molecule, organism pattern recognition receptor (PRRs) can recognize pathogens and induce antiviral immune response in the early stage of viral infection. This paper describes the definition of PRRs. The type and signal pathway were divided into Toll like receptor family and Toll independent pattern recognition receptor family. The relationship between them and hepatitis B virus infection was introduced.
【作者單位】: 安徽醫(yī)科大學(xué)附屬省立醫(yī)院感染病科;南京醫(yī)科大學(xué)第一附屬醫(yī)院感染病科;
【基金】:國(guó)家自然科學(xué)基金項(xiàng)目(編號(hào):81271713) Gilead Sciences Research Scholars Program in Liver Disease亞洲項(xiàng)目
【分類號(hào)】:R512.62
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本文編號(hào):1663639

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