本文選題：乙肝后肝硬化　切入點(diǎn)：CT肝臟體積　出處：《山東醫(yī)藥》2017年16期

【摘要】：目的探討CT肝臟體積在乙肝后肝硬化程度量化診斷的價(jià)值。方法選擇乙肝后肝硬化患者30例,肝組織活檢術(shù)前1周行64層螺旋CT薄層掃描+三期增強(qiáng)掃描,將獲得的數(shù)據(jù)導(dǎo)入Mimics10.01軟件,進(jìn)行肝臟三維立體重建并計(jì)算CT肝臟體積。術(shù)前評(píng)估患者肝硬化臨床分期,計(jì)算終末期肝病模型(MELD)評(píng)分。分析CT肝臟體積與肝組織病理分級(jí)、肝硬化臨床分期和MELD評(píng)分的關(guān)系。結(jié)果 30例患者CT肝臟體積明顯小于理論肝臟體積(P0.05)。肝組織病理分級(jí)4A、4B、4C級(jí)者,肝硬化臨床分期1、2、3、4期者,MELD評(píng)分10分、≥10~20分、≥20~30分者CT肝臟體積比較差異均有統(tǒng)計(jì)學(xué)意義(P均0.05)。相關(guān)分析顯示,肝組織病理分級(jí)、肝硬化臨床分期和MELD評(píng)分均與CT肝臟體積呈負(fù)相關(guān)(r分別為-0.55、-0.78及-0.52,P均0.01)。結(jié)論CT肝臟體積可作為乙肝后肝硬化程度的一個(gè)量化診斷指標(biāo);CT肝臟體積越小,肝組織病理分級(jí)越重、臨床分期等級(jí)越高、MELD評(píng)分越高。
[Abstract]:Objective to evaluate the value of CT liver volume in the quantitative diagnosis of liver cirrhosis after hepatitis B. methods Thirty patients with liver cirrhosis after hepatitis B were examined with three-phase enhanced spiral CT scanning one week before liver biopsy. The obtained data were imported into Mimics10.01 software to reconstruct the liver three-dimensional and calculate the CT liver volume. The clinical stage of liver cirrhosis was evaluated before operation, and the end stage liver disease model was evaluated. The liver volume and pathological grade of liver tissue were analyzed. Results the CT liver volume of 30 patients was significantly smaller than that of theoretical liver volume (P0.05). The difference of CT liver volume was statistically significant in patients with liver volume 鈮，

本文編號(hào)：1663532