本文關(guān)鍵詞：2009-2014年云南省登革熱流行病學(xué)調(diào)查與分析　出處：《中國病原生物學(xué)雜志》2015年08期 　論文類型：期刊論文

  更多相關(guān)文章： 登革熱 流行病學(xué) 埃及伊蚊 云南省

【摘要】：目的分析云南省2009-2014年登革熱流行特征,為登革熱防控措施提供依據(jù)。方法收集云南省2009-2014年法定傳染病報告系統(tǒng)中的登革熱數(shù)據(jù)資料,采用描述性流行病學(xué)方法統(tǒng)計分析;采用RT-PCR檢測登革病毒血清型和采用蚊蟲幼蟲采集法調(diào)查登革熱媒介埃及伊蚊的分布。結(jié)果 2009-2014年云南省共報告登革熱病例2 040例,其中本地感染病例1 579例,輸入病例461例;在輸入病例中,緬甸和老撾輸入病例比例最高(占79.83%);全年均有病例報告,8~11月為高發(fā)季節(jié);病例主要集中于云南邊境地區(qū)的西雙版納州(1 382例,占67.75%)和德宏州(562例,占27.55%);男女比例為1.05∶1,各年齡組均有發(fā)病,以青壯年為主,20~59歲病例1 538例(占75.39%),職業(yè)以商業(yè)服務(wù)、家務(wù)及待業(yè)、農(nóng)民和學(xué)生為主,分別為523例(占25.64%)、224例(占10.98%)214例(占10.49)和200例(占9.80%)。對景洪市307份血清用RT-PCR和NS1抗原進行檢測,兩種方法吻合率在70%以上,NS1抗原檢測方法敏感度為86.39%,特異度為57.76%;對瑞麗市73份血清用一步法實時熒光RT-PCR檢測進行復(fù)核,NS1抗原檢測方法敏感度為100%,特異度為91.67%;4個登革病毒血清型在云南均有發(fā)現(xiàn),其中西雙版納州景洪市以登革病毒血清型Ⅲ型為主(99.50%),德宏州瑞麗市以Ⅰ型為主(72.00%);白紋伊蚊廣泛分布,埃及伊蚊分布區(qū)擴大到9個邊境縣市。結(jié)論云南省登革熱流行勢態(tài)較為嚴(yán)峻,周邊緬甸和老撾輸入病例數(shù)逐年增加,媒介埃及伊蚊分布區(qū)域不斷擴大,建議進一步加強云南邊境地區(qū)登革熱監(jiān)測和媒介控制工作。
[Abstract]:Objective to analyze the epidemic characteristics of dengue fever in Yunnan Province from 2009 to 2014. Methods Dengue fever data were collected from the legal infectious disease reporting system in Yunnan Province from 2009 to 2014, and descriptive epidemiological methods were used to analyze the data. The distribution of dengue vector Aedes aegypti was investigated by RT-PCR detection of dengue virus serotype and mosquito larva collection. Results A total of dengue fever cases 2 were reported in Yunnan Province from 2009 to 2014. 040 cases. There were 1 579 cases of local infection and 461 cases of imported cases. Myanmar and Laos had the highest proportion of imported cases (79.83%). Cases were reported from 8 to November as the high incidence season in the whole year. There were 1 382 cases in Xishuangbanna prefecture (67.75%) and 562 cases in Dehong Prefecture (27.5555%). The ratio of male to female was 1.05: 1. All age groups had the disease. There were 1 538 cases (75.399%) of male and female aged 2059 years old. The occupation was business service, housework and unemployment. 523 cases (25.64%) were farmers and students respectively. 224 cases (10.98%) and 200 cases (9.80%) were tested for RT-PCR and NS1 antigens in 307 serum samples in Jinghong city. The sensitivity and specificity of the two methods were 86.39 and 57.76, respectively. The sensitivity and specificity of the method for detecting NS1 antigen in 73 sera from Ruili city were 100 and 91.67, respectively. Four dengue virus serotypes were found in Yunnan, of which 99.50m were mainly dengue virus serotype 鈪，

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