本文關(guān)鍵詞：207例帶狀皰疹臨床特征及預(yù)后因素分析　出處：《南京醫(yī)科大學(xué)學(xué)報(bào)(自然科學(xué)版)》2017年11期 　論文類型：期刊論文

  更多相關(guān)文章： 帶狀皰疹 后遺神經(jīng)痛 預(yù)后 危險(xiǎn)因素

【摘要】：目的 :探討帶狀皰疹的臨床特征及預(yù)后因素。方法 :收集2008年1月—2015年12月住院確診的207例帶狀皰疹患者的臨床資料,對(duì)其發(fā)病年齡、性別、基礎(chǔ)疾病、發(fā)病誘因、數(shù)字分級(jí)量表(numerical rating scale,NRS)評(píng)分、皮損分布與嚴(yán)重程度、實(shí)驗(yàn)室檢查、治療與預(yù)后進(jìn)行回顧性分析,進(jìn)一步利用Logistic回歸分析對(duì)帶狀皰疹后遺神經(jīng)痛的危險(xiǎn)因素進(jìn)行分析。結(jié)果:207例住院帶狀皰疹患者平均發(fā)病年齡(63.1±16.0)歲,發(fā)病無(wú)明顯性別差異,17.4%患者合并2種以上基礎(chǔ)疾病,51.2%患者發(fā)病前有明確誘因,60.4%患者具有前驅(qū)期疼痛,21.7%患者病程中伴有發(fā)熱、皮損,以累及三叉神經(jīng)眼支者最多,占36.7%;入院時(shí)NRS評(píng)分和皮損嚴(yán)重程度評(píng)分為中度或重度的患者占90%以上。治療后19例發(fā)生帶狀皰疹后遺神經(jīng)痛,1例遺留右上肢運(yùn)動(dòng)性麻痹。與同期門診診治的252例帶狀皰疹患者相比,住院帶狀皰疹患者帶狀皰疹后遺神經(jīng)痛的發(fā)生率明顯高于門診患者(χ2=9.224,P0.01)。Logistic回歸分析顯示皮損累及胸神經(jīng)分布區(qū)、NRS評(píng)分高是發(fā)生帶狀皰疹后遺神經(jīng)痛的主要危險(xiǎn)因素。結(jié)論:臨床上應(yīng)加強(qiáng)識(shí)別帶狀皰疹后遺神經(jīng)痛的危險(xiǎn)因素,早期進(jìn)行規(guī)范與合理治療。
[Abstract]:Objective: to investigate the clinical features and prognostic factors of herpes zoster. Methods: the clinical data of 207 cases of herpes zoster diagnosed in hospital from January 2008 to December 2015 were collected. The age, sex, basic disease, inducement, numerical rating scale (NRS) score, skin lesion distribution and severity were evaluated. Laboratory examination, treatment and prognosis were retrospectively analyzed. Logistic regression analysis was used to analyze the risk factors of postherpetic neuralgia. Results the mean onset age was 63.1 鹵16.0 in #number0# patients with herpes zoster. Years old. There was no significant gender difference in the incidence rate of 17.4% patients with two or more basic diseases. 51.2% patients had definite inducement before onset. 60.4% patients had pain in the precursor phase. 21.7% patients with fever, skin lesions, the most involved in the trigeminal nerve ophthalmic branch, 36.7 percent; At the time of admission, more than 90% patients had moderate or severe NRS score and severity of skin lesions. After treatment, 19 patients developed postherpetic neuralgia. A case of left right upper limb motor palsy was compared with 252 cases of herpes zoster treated in outpatient clinic at the same time. The incidence of postherpetic neuralgia in patients with herpes zoster was significantly higher than that in outpatients (蠂 2 / 9.224). Logistic regression analysis showed that the area of thoracic nerve was involved in the lesion. High NRS score was the main risk factor for the occurrence of postherpetic neuralgia. Conclusion: the clinical risk factors of postherpetic neuralgia should be recognized and standardized and reasonably treated in the early stage.
【作者單位】： 蘇州大學(xué)附屬第一醫(yī)院皮膚科;
【基金】：江蘇省自然科學(xué)基金青年基金(BK20140294)
【分類號(hào)】：R752.12
【正文快照】： 帶狀皰疹是皮膚科臨床中的常見(jiàn)病,由水痘-帶狀皰疹病毒感染引起,常伴明顯的神經(jīng)痛,愈后可發(fā)生帶狀皰疹后遺神經(jīng)痛。2008年1月—2015年12月本科共收治207例帶狀皰疹住院患者,現(xiàn)對(duì)其臨床資料進(jìn)行回顧性分析,并探討發(fā)生帶狀皰疹后遺神經(jīng)痛的危險(xiǎn)因素。1對(duì)象和方法1.1對(duì)象收集2008

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