本文關(guān)鍵詞：載藥醫(yī)用硫酸鈣顆粒局部植骨治療骶髂關(guān)節(jié)結(jié)核　出處：《中國(guó)修復(fù)重建外科雜志》2015年04期 　論文類型：期刊論文

  更多相關(guān)文章： 骶髂關(guān)節(jié)結(jié)核 醫(yī)用硫酸鈣 利福平緩釋體 轉(zhuǎn)化醫(yī)學(xué)

【摘要】：目的分析醫(yī)用硫酸鈣與注射用利福平粉末混合植骨治療骶髂關(guān)節(jié)結(jié)核病灶清除后骨缺損的安全性、可行性和療效。方法回顧分析2006年8月-2010年8月采用一期病灶清除、醫(yī)用硫酸鈣加注射用利福平局部植骨治療的27例骶髂關(guān)節(jié)結(jié)核患者臨床資料。其中男10例,女17例;年齡16~64歲,平均35.2歲。病程1.5~16個(gè)月,平均7.5個(gè)月。病變位于左側(cè)16例,右側(cè)10例,雙側(cè)1例。其中伴髂窩膿腫18例,臀部膿腫6例。根據(jù)Kim分型,Ⅲ型9例,Ⅳ型18例。術(shù)前Majeed評(píng)分為(61.23±6.49)分;良4例、中19例、差4例,優(yōu)良率14.81%。結(jié)果術(shù)后傷口均I期愈合,無(wú)骨盆感染、周圍神經(jīng)損傷、下肢深靜脈血栓形成等并發(fā)癥發(fā)生。26例獲隨訪,隨訪時(shí)間12~24個(gè)月,平均16個(gè)月。腰骶及下肢活動(dòng)、感覺(jué)均正常,無(wú)會(huì)陰感覺(jué)障礙。除1例耐多藥結(jié)核患者于術(shù)后3個(gè)月局部復(fù)發(fā),經(jīng)調(diào)整抗結(jié)核藥物及營(yíng)養(yǎng)支持,應(yīng)用胸腺五肽增強(qiáng)免疫治療,二次病灶清除術(shù)后治愈。25例患者均于術(shù)后9~12個(gè)月植骨融合,且癥狀消失,病灶無(wú)復(fù)發(fā),恢復(fù)病前工作。末次隨訪時(shí)Majeed評(píng)分為(92.31±3.36)分,與術(shù)前比較差異有統(tǒng)計(jì)學(xué)意義(t=—32.76,P=0.00);獲優(yōu)22例,良4例,優(yōu)良率100%,與術(shù)前比較差異有統(tǒng)計(jì)學(xué)意義(χ2=31.93,P=0.00)。結(jié)論載有注射用利福平醫(yī)用硫酸鈣顆粒植骨融合是治療骶髂關(guān)節(jié)結(jié)核病灶清除后骨缺損的安全、有效方法。
[Abstract]:Objective to analyze the safety of bone graft with medical calcium sulfate and rifampicin powder for treatment of sacroiliac joint tuberculosis after clearance. Methods one stage debridement was performed from August 2006 to August 2010. Clinical data of 27 cases of sacroiliac joint tuberculosis treated with medical calcium sulfate and rifampicin local bone grafting, including 10 males and 17 females; The mean age was 35.2 years. The course of disease was 1.5 ~ 16 months (mean 7.5 months). The lesions were located in left side in 16 cases, right side in 10 cases and bilateral side in 1 case, including 18 cases with iliac fossa abscess. There were 6 cases of hip abscess. According to Kim classification, there were 9 cases of type 鈪，

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