【摘要】：目的探討迭代重組iDose4技術(shù)和基于模型的全迭代重組(IMR)技術(shù)在胃腸道腫瘤術(shù)后低劑量隨訪中的應(yīng)用價(jià)值,并比較迭代重組i Dose4和IMR對(duì)圖像質(zhì)量的影響。方法將30例胃腸道腫瘤術(shù)后患者納入此項(xiàng)研究。在初診和6個(gè)月后復(fù)診時(shí)分別進(jìn)行腹部CT平掃和增強(qiáng)(常規(guī)劑量和低劑量)掃描,采用濾波反投影(FBP)技術(shù)重組常規(guī)劑量掃描圖像門靜脈期原始數(shù)據(jù),采用迭代重組iDose4技術(shù)和IMR技術(shù)重組低劑量掃描圖像門靜脈期原始數(shù)據(jù),得到3組圖像,包括A組(常規(guī)劑量組)、B1組(低劑量i Dose4組)、B2組(低劑量IMR組),將門靜脈期掃描數(shù)據(jù)作為研究對(duì)象,對(duì)圖像進(jìn)行客觀和主觀分析,客觀分析包括測(cè)量肝臟的CT值,噪聲及信噪比(SNR),主觀分析包括對(duì)圖像進(jìn)行質(zhì)量評(píng)分,并比較輻射劑量。結(jié)果低劑量掃描較常規(guī)劑量掃描輻射劑量平均降低了51.47%(P0.05)。圖像主觀評(píng)分差異無統(tǒng)計(jì)學(xué)意義(P0.01),三組圖像均能滿足診斷要求。圖像客觀評(píng)價(jià)中,三組圖像CT值相仿(P0.05),差異無統(tǒng)計(jì)學(xué)意義。三組圖像的噪聲、SNR值和對(duì)比噪聲比(CNR)值之間的差異有統(tǒng)計(jì)學(xué)意義(P0.05),B1組較A組之間圖像噪聲和SNR值之間的差異均無統(tǒng)計(jì)學(xué)意義(P0.05),B2組較A組圖像噪聲明顯降低、SNR值明顯提高,差異均有統(tǒng)計(jì)學(xué)意義(P0.01),B1組與B2組較A組CNR值均提高,差異均有統(tǒng)計(jì)學(xué)意義(P0.01),B2組提高更顯著,且B1與B2組之間差異有統(tǒng)計(jì)學(xué)意義(P0.01)。結(jié)論采用迭代重組i Dose4技術(shù)和IMR技術(shù),對(duì)胃腸道腫瘤患者術(shù)后進(jìn)行低劑量CT隨訪,在大幅降低輻射劑量的同時(shí)均能保證圖像質(zhì)量可滿足診斷要求,并且迭代重組IMR技術(shù)較iDose4技術(shù)的圖像噪聲低、圖像質(zhì)量高。
[Abstract]:Objective to investigate the application value of iterative recombinant iDose4 technique and model-based total iterative recombinant (IMR) technique in low-dose follow-up of gastrointestinal neoplasms, and to compare the effects of iterative recombination I Dose4 and IMR on image quality. Methods 30 patients with gastrointestinal neoplasms after operation were included in the study. Abdominal CT plain scan and enhancement (conventional dose and low dose) scan were performed at first visit and 6 months later. The original data of portal vein phase were reconstructed by filtered backprojection (FBP) technique. The original data of portal vein phase of low-dose scanning images were reconstructed by iterative recombination iDose4 technique and IMR technique. Three groups of images were obtained, including group A (routine dose group), group B1 (low dose I Dose4 group), group B2 (low dose IMR group), group B (low dose IMR group). The scanning data of portal vein were used as the object of study. The objective analysis included the measurement of CT value of liver, the subjective analysis of noise and signal-to-noise ratio (SNR), including the evaluation of image quality, and the comparison of radiation dose. Results the average radiation dose of low dose scan was 51.47% lower than that of conventional dose scan (P0.05). There was no significant difference in image subjective score (P0.01). All three groups of images could meet the diagnostic requirements. In the objective evaluation of images, the CT values of the three groups were similar (P0.05), the difference was not statistically significant. The difference of noise, SNR value and contrast noise ratio between three groups was statistically significant (P0.05), but there was no significant difference between group B1 and group A in image noise and SNR value (P0.05). The image noise and SNR value of group B2 were significantly lower than those of group A (P0.01). The CNR values of group B1 and group B2 were significantly higher than those of group A (P0.01), and the increase of CNR in group B2 was more significant than that in group A (P0.01). There was significant difference between group B1 and group B2 (P0.01). Conclusion by using iterative recombination I Dose4 and IMR techniques to follow up the patients with gastrointestinal cancer with low dose CT, the image quality can be guaranteed to meet the diagnostic requirements while the radiation dose is significantly reduced. And the iterative recombination IMR technique has lower image noise and higher image quality than iDose4 technology.
【作者單位】： 南京醫(yī)科大學(xué)鼓樓臨床醫(yī)學(xué)院;南京大學(xué)醫(yī)學(xué)院附屬鼓樓醫(yī)院;
【基金】：南京市醫(yī)學(xué)科技發(fā)展一般性課題資助項(xiàng)目(編號(hào):YKK13078) 江蘇省衛(wèi)生廳青年科研課題資助項(xiàng)目(編號(hào):Q201411)
【分類號(hào)】：R445.2;R735

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