發(fā)布時間：2018-11-16 10:02

【摘要】：背景與目的淋巴結(jié)轉(zhuǎn)移是影響肺癌腫瘤-淋巴結(jié)-轉(zhuǎn)移(tumor-node-matastasis,TNM)分期的重要因素之一,在非小細(xì)胞肺癌(non-small cell lung cancer,NSCLC)患者的手術(shù)中,13組、14組淋巴結(jié)因其隱藏于肺葉的深部而忽視做病理檢測,影響術(shù)后病理分期準(zhǔn)確性。本研究旨在探討13組、14組淋巴結(jié)在NSCLC術(shù)中的陽性檢出率及其對病理分期的影響。方法選取內(nèi)蒙古醫(yī)科大學(xué)附屬醫(yī)院100例NSCLC手術(shù)患者為研究對象,剖取胸內(nèi)2組-12組、第13、14組淋巴結(jié)行病理檢測,分析腫瘤的大小、部位、病理類型等因素與胸內(nèi)淋巴結(jié)轉(zhuǎn)移率的關(guān)系。結(jié)果 100例患者胸內(nèi)淋巴結(jié)轉(zhuǎn)移率為47.0%,10組-12組、N2淋巴結(jié)、13組、14組淋巴結(jié)陽性率有統(tǒng)計學(xué)差異(P0.05);不同T分期13組、14組淋巴結(jié)漏檢率有統(tǒng)計學(xué)差異(P0.05);周圍型與中央型NSCLC的N1期漏檢率無統(tǒng)計學(xué)差異(P0.05);不同病理類型腫瘤之間N1期漏診率無統(tǒng)計學(xué)差異(P0.05)。此外,發(fā)現(xiàn)有12例患者存在非腫瘤所在葉、段支氣管旁淋巴結(jié)轉(zhuǎn)移。結(jié)論臨床上檢測NSCLC 13組、14組與非腫瘤所在葉支氣管旁淋巴結(jié)的轉(zhuǎn)移情況十分必要,有利于獲取術(shù)后準(zhǔn)確的TNM分期,對于指導(dǎo)術(shù)后治療意義重大。
[Abstract]:Background & objective lymph node metastasis is one of the important factors influencing the staging of tumor lymph node metastasis (tumor-node-matastasis,TNM) of lung cancer. In 13 groups of patients with non-small cell lung cancer (non-small cell lung cancer,NSCLC). The lymph nodes in 14 groups were neglected by pathological examination because they were hidden in the deep part of the lung lobe, which affected the accuracy of postoperative pathological staging. The purpose of this study was to investigate the positive rate of lymph nodes in 13 groups and 14 groups during NSCLC and its influence on pathological staging. Methods A total of 100 patients undergoing NSCLC operation in Inner Mongolia Medical University Hospital were selected as subjects. The lymph nodes in group 1314 were examined by pathological examination, and the size and location of the tumor were analyzed. The relationship between pathological type and intrathoracic lymph node metastasis rate. Results the positive rates of intrathoracic lymph node metastasis in 100 patients were 47.0% and 47.0% respectively. The positive rates of lymph nodes in 10 groups, N2 lymph nodes, 13 groups, 14 groups were significantly different (P0.05). In 13 groups with different T stages, there was statistical difference in the rate of lymph node leakage in 14 groups (P0.05), but there was no statistical difference between peripheral type and central type of NSCLC in N1 stage (P0.05). There was no significant difference in missed diagnosis rate between different pathological types of tumors at N1 stage (P0.05). In addition, 12 patients with non-tumor lobes and segmental parabranchial lymph node metastasis were found. Conclusion it is necessary to detect the lymph node metastasis in group NSCLC 13, group 14 and non-tumor, which is helpful to obtain accurate TNM staging after operation, and is of great significance in guiding postoperative treatment.
【作者單位】： 內(nèi)蒙古醫(yī)科大學(xué)附屬醫(yī)院胸外科;
【基金】：內(nèi)蒙古自治區(qū)自然科學(xué)基金項目(No.2014MS08102)資助~~
【分類號】：R734.2

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