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紅花注射液對乳腺癌術(shù)后上肢淋巴水腫臨床療效的影響

發(fā)布時間:2018-05-28 03:19

  本文選題:乳腺癌手術(shù) + 上肢淋巴水腫; 參考:《遼寧中醫(yī)藥大學(xué)》2017年碩士論文


【摘要】:目的:將紅花注射液應(yīng)用于乳腺癌改良根治術(shù)后上肢淋巴水腫的患者,通過評價患者治療前后的患側(cè)上肢周徑、水腫分級及臨床療效的改善情況,評價用紅花注射液治療乳腺癌改良根治術(shù)后上肢淋巴水腫患者的療效,為今后臨床上應(yīng)用中醫(yī)藥治療乳腺癌改良根治術(shù)后上肢淋巴水腫提供臨床依據(jù)。材料與方法:選擇2015年1月至2016年10月在遼寧省腫瘤醫(yī)院接受乳腺癌改良根治手術(shù)后發(fā)生上肢水腫的患者49例,年齡在31至64周歲之間。按手術(shù)時間和隨機數(shù)字表分為觀察組(25例)和對照組(24例)。兩組對象均接受我科乳腺癌術(shù)后上肢水腫常規(guī)治療,包括低鹽飲食、彈力繃帶加壓包扎的壓迫療法、壓迫療法下的上肢功能鍛煉和患肢物理療法等。觀察組給予靜脈滴注紅花注射液,連續(xù)用藥30天。將兩組患者患側(cè)上肢周徑及水腫程度進行比較,從而評估紅花注射液對乳腺癌改良根治術(shù)后上肢淋巴水腫的臨床療效。結(jié)果:1兩組患者發(fā)病年齡、發(fā)生上肢水腫距乳腺癌改良根治術(shù)后時間及上肢水腫嚴重程度比較無統(tǒng)計學(xué)差異(P0.05)。2生物學(xué)指標比較:兩組對象治療前患肢上臂圍、前臂圍測試值分布接近(P0.05);治療結(jié)束后,觀察組患肢上臂圍、前臂圍測試值明顯低于治療前及對照組同期結(jié)果(P0.05)。3臨床療效指標比較:觀察組中顯效5例(20.00%)和有效16例(64.00%),總有效率84.00%,無效4例(16.00%),明顯優(yōu)于對照組。結(jié)論:1紅花注射液能夠縮小乳腺癌改良根治術(shù)后患側(cè)上肢淋巴水腫的上肢周徑,減輕水腫程度。2靜脈滴注紅花注射液的觀察組明顯優(yōu)于對照組。3紅花注射液治療乳腺癌改良根治術(shù)后上肢淋巴水腫的療效確切。
[Abstract]:Objective: to apply safflower injection to the patients with upper limb lymphedema after modified radical mastectomy. To evaluate the therapeutic effect of safflower injection on upper limb lymphedema after modified radical mastectomy, and to provide clinical basis for the treatment of upper limb lymphedema after modified radical mastectomy with traditional Chinese medicine. Materials and methods: 49 patients with upper limb edema after modified radical mastectomy were selected from January 2015 to October 2016 in Liaoning Cancer Hospital, aged between 31 and 64 years. According to the operation time and random number table, the observation group (n = 25) and the control group (n = 24) were divided into two groups. The two groups received routine treatment of upper limb edema after breast cancer operation, including low-salt diet, compression therapy with elastic bandage, upper limb function exercise and physical therapy of affected limbs, etc. In the observation group, safflower injection was given intravenously for 30 days. In order to evaluate the clinical effect of safflower injection on upper limb lymphedema after modified radical mastectomy, the peripheral diameter and edema degree of upper extremity were compared between the two groups. Results there was no significant difference in the age of onset, the time between the onset of upper limb edema and the time after modified radical mastectomy and the severity of upper limb edema between the two groups. The distribution of the forearm circumference was close to that of P0.05.After the treatment, the upper arm circumference of the affected limb was observed in the observation group. The value of forearm circumference test was significantly lower than that before treatment and the control group (P 0.053.Compared with the clinical curative effect index: in the observation group, 5 cases had remarkable effect (20. 00) and 16 cases were effective, the total effective rate was 84. 00 and 4 cases were ineffective, which was obviously superior to that of the control group. Conclusion 1 safflower injection can reduce the peripheral diameter of upper limb lymphedema in the affected side after modified radical mastectomy. The observation group was better than the control group in the treatment of upper limb lymphedema after modified radical mastectomy, and the observation group was superior to the control group in the treatment of upper limb lymphedema after modified radical mastectomy.
【學(xué)位授予單位】:遼寧中醫(yī)藥大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2017
【分類號】:R737.9

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