發(fā)布時(shí)間：2018-04-13 16:34

  本文選題：基底細(xì)胞腫瘤 + 病理分型��； 參考：《臨床與實(shí)驗(yàn)病理學(xué)雜志》2017年01期

【摘要】：目的探討面部不同分型基底細(xì)胞癌(basal cell carcinoma,BCC)的臨床病理特征、切緣情況及影響因素。方法回顧性分析300例BCC的臨床病理特征及不同手術(shù)切緣下的術(shù)中冷凍切緣情況及影響因素,并復(fù)習(xí)相關(guān)文獻(xiàn)。利用Logistic多元回歸模型分析BCC病理分型、手術(shù)切緣、腫瘤直徑及發(fā)生位置等對(duì)首次術(shù)中冷凍切緣陽(yáng)性率的影響。結(jié)果 Logistic多元回歸分析顯示病理分型是首次術(shù)中冷凍切緣陽(yáng)性率的主要危險(xiǎn)因素;浸潤(rùn)型(OR=4.463,95%CI=1.919~10.380,P0.05)和硬斑病樣型(OR=5.018,95%CI=2.025~16.623,P0.05)與結(jié)節(jié)型BCC相比,發(fā)生切緣陽(yáng)性的風(fēng)險(xiǎn)較高;在不同切緣下,結(jié)節(jié)型、淺表型BCC切緣陽(yáng)性率差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論病理分型是影響B(tài)CC手術(shù)切緣安全的獨(dú)立因素;面部結(jié)節(jié)型、淺表型BCC,采用3 mm手術(shù)切緣可達(dá)理想手術(shù)效果。
[Abstract]:Objective to investigate the clinicopathological features, incisal margin and influencing factors of basal cell carcinoma (BCC) in different facial classification.Methods the clinicopathological features of 300 cases of BCC were analyzed retrospectively.Logistic multivariate regression model was used to analyze the effects of pathological classification, surgical margin, tumor diameter and location of tumor on the positive rate of frozen margin in the first operation.Results Logistic multivariate regression analysis showed that pathological classification was the main risk factor for the positive rate of freeze-cut margin in the first operation, and the invasive type ORA 4.463 + 95 CI1.919 ~ 10.380 (P0.05) and hard spot disease type OR5.018 ~ 95CII 2.025252516.623P0.05) had a higher risk of positive margin than that of nodular BCC, and the risk of positive margin was higher than that of nodular BCC, and the risk of positive margin was higher than that of nodular BCC.There was no significant difference in the positive rate of BCC margin between nodular type and superficial type (P 0.05).Conclusion pathological classification is an independent factor affecting the safety of BCC surgical margin, and the facial nodular and superficial BCCs can achieve satisfactory results with 3 mm surgical margin.
【作者單位】： 安徽醫(yī)科大學(xué)附屬省立醫(yī)院整形外科;安徽醫(yī)科大學(xué)附屬省立醫(yī)院病理科;
【分類號(hào)】：R739.5

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 鄧京平;鐘晨陽(yáng);萬(wàn)奔;張傳禮;魏東;鄧庶民;王建業(yè);;前列腺癌根治術(shù)中避免手術(shù)切緣陽(yáng)性的臨床評(píng)價(jià)[J];醫(yī)學(xué)研究雜志;2008年03期

2 梅麗;劉婷婷;李麗;;育齡期婦女宮頸上皮內(nèi)瘤變錐切治療后切緣陽(yáng)性的高危因素分析[J];中國(guó)醫(yī)藥科學(xué);2013年12期

3 \盒〗，

本文編號(hào)：1745311