本文選題：宮頸癌　切入點(diǎn)：癌前病變　出處：《臨床和實(shí)驗(yàn)醫(yī)學(xué)雜志》2017年24期 　論文類型：期刊論文

【摘要】：目的探討經(jīng)陰道超高速剪切波彈性成像對(duì)宮頸癌及癌前病變的診斷作用。方法回顧性分析2014年5月至2017年5月期間收治的48例宮頸惡性病變患者的臨床資料,比較宮頸癌組(n=18)、宮頸上皮內(nèi)瘤變(CIN)組(n=30)和體檢健康、宮頸無(wú)病變的對(duì)照組(n=53)的宮頸彈性成像硬度評(píng)分、平均彈性成像硬度評(píng)分診斷宮頸癌的敏感度和特異度、感興趣區(qū)域彈性模量最大值和平均值、彈性模量最大值和平均值診斷宮頸癌及CIN的ROC曲線下面積。結(jié)果宮頸癌組的平均彈性成像硬度評(píng)分為(3.93±0.08)分,均分別高于對(duì)照組的(1.05±0.03)分、CIN的組(2.12±0.06)分,差異有顯著性(P0.05)。以評(píng)分≥3分診斷為宮頸癌,其敏感度為94.44%,特異度為88.89%。宮頸癌組感興趣區(qū)域彈性模量最大值及平均值最高,與CIN組、對(duì)照組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。宮頸癌彈性模量最大值及平均值診斷宮頸癌的ROC曲線下面積分別為0.92、0.75(Z=3.541,P0.05)。結(jié)論經(jīng)陰道超高速剪切波彈性成像技術(shù)可定量分析宮頸組織軟硬度,有利于篩查早期宮頸癌,并可通過(guò)彩色編碼篩查浸潤(rùn)程度,但對(duì)癌前病變的診斷價(jià)值并不明顯。
[Abstract]:Objective to investigate the role of transvaginal ultra-high speed shear wave elastography in the diagnosis of cervical cancer and precancerous lesions. Methods the clinical data of 48 patients with cervical malignant lesions from May 2014 to May 2017 were retrospectively analyzed. The sensitivity and specificity of cervical elastography hardness score and mean elastography hardness score were compared between cervical carcinoma group (n = 18), cervical intraepithelial neoplasia group (n = 30) and healthy control group (n = 53). The area under the ROC curve of cervical cancer and CIN was diagnosed by the maximum and average elastic modulus of the region of interest. Results the average elastic imaging hardness score of cervical cancer group was 3.93 鹵0.08. The difference was significant (P < 0.05). The sensitivity and specificity of diagnosis of cervical cancer with score 鈮，

本文編號(hào)：1642291