血小板增高與非小細胞肺癌發(fā)生骨轉(zhuǎn)移的相關(guān)性探討
發(fā)布時間:2018-02-08 15:22
本文關(guān)鍵詞: 非小細胞肺癌 血小板升高 遠處轉(zhuǎn)移 骨轉(zhuǎn)移 出處:《青海大學》2017年碩士論文 論文類型:學位論文
【摘要】:目的通過測量患有NSCLC血液外循環(huán)系統(tǒng)的的血小板計數(shù),來進行討論其和患者發(fā)生人體骨轉(zhuǎn)移有無關(guān)聯(lián)。方法通過選取2015年10月到2016年10月經(jīng)青大附院病理學診斷為NSCLC的行住院治療的病人。排除掉患有其它影響病人外周血血小板計數(shù)的先天的或后天的疾病的病例后,最終收納入資料較齊的病人206個,其中血小板大于300×109/L的暫定義為研究組(A),而相較于參考標準而言正常的為對照組(B)緊接著我們對這兩組之間在其初診的時候和在其在病程中發(fā)生的骨轉(zhuǎn)移的數(shù)目通過統(tǒng)計學上的對比分析,得出相應的統(tǒng)計上的結(jié)論。結(jié)果在A組中初次就診的病人有骨轉(zhuǎn)移的數(shù)目是19例,另一組中發(fā)生的例數(shù)則是17例。這2者相互進行比較的話是有統(tǒng)計學上的差異的。(X2=10.67P=0.0018)然后再把A組根據(jù)程度進行分組,進行比較后得出組間具有統(tǒng)計學上的差異,其升高程度與其發(fā)生轉(zhuǎn)移的比率成正相關(guān)。結(jié)論在患有NSCLC的病人中,其外周血循環(huán)中血小板的增多和其發(fā)生骨轉(zhuǎn)移是有關(guān)的;血小板計數(shù)增多的病人其骨轉(zhuǎn)移的可能性增大且與其增多的程度呈正相關(guān)。
[Abstract]:Objective to measure the platelet count in the external circulatory system of patients with NSCLC. Methods patients with NSCLC diagnosed as NSCLC by pathology from October 2015 to 2016 were selected and excluded from other affected patients. Peripheral blood platelets count in cases of congenital or acquired diseases, In the end, 206 patients with more accurate data were accepted, Where platelets greater than 300 脳 109 / L are tentatively defined as the study group, and as normal as the control group compared to the reference criteria, then we have a general understanding of the number of bone metastases that occur between the two groups at the time of their initial diagnosis and during the course of their disease. Through statistical comparative analysis, Results the number of bone metastases in group A was 19. In the other group, there were 17 cases. There was a statistical difference between the two groups, and then the group A was grouped according to the degree, and the difference between the two groups was statistically significant. Conclusion in patients with NSCLC, the increase of platelet in peripheral blood circulation is related to the occurrence of bone metastasis. Patients with increased platelet count were more likely to have bone metastases and had a positive correlation with the degree of increase.
【學位授予單位】:青海大學
【學位級別】:碩士
【學位授予年份】:2017
【分類號】:R734.2
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