本文關(guān)鍵詞：山西省中西醫(yī)結(jié)合治療SARS臨床回顧性研究，由筆耕文化傳播整理發(fā)布。

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山西醫(yī)科大學(xué)碩士學(xué)位論文山西省中西醫(yī)結(jié)合治療SARS臨床回顧性研究姓名:宋曉慧申請(qǐng)學(xué)位級(jí)別:碩士專業(yè):中西醫(yī)結(jié)合臨床指導(dǎo)教師:張劍宇20040518山西醫(yī)科大學(xué)碩士學(xué)位論文山西省中西醫(yī)結(jié)合治療SARS臨床回顧性研究摘要目的:探討中醫(yī)藥參與、中西醫(yī)結(jié)合治療SARS的有效性與最佳切入點(diǎn)。資料與方法:調(diào)閱山西省430例臨床診斷病例,印制病例報(bào)告表進(jìn)行數(shù)據(jù)采集,用EPIdata3.0軟件建立數(shù)據(jù)庫(kù),編制數(shù)據(jù)錄入程序,對(duì)錄入數(shù)據(jù)進(jìn)行清理、核查、鎖定,撰寫統(tǒng)計(jì)分析報(bào)告書,用SAS8.2軟件編程進(jìn)行統(tǒng)計(jì)分析。采用回顧性隊(duì)列研究的方法,對(duì)山西省臨床診斷的430例SARS病人的臨床癥狀、體征、胸部x線片、實(shí)驗(yàn)室檢測(cè)指標(biāo)、影響疾病轉(zhuǎn)歸的多種因素進(jìn)行多層次、多側(cè)面、多角度分析。結(jié)果:中西醫(yī)結(jié)合組與單純西醫(yī)治療組兩組間人口學(xué)資料均衡可比(P>O.05);中西醫(yī)結(jié)合組患基礎(chǔ)疾病者比率高于西醫(yī)組(P<O.05);中西醫(yī)結(jié)合組入院時(shí)的病情重于單純西醫(yī)治療組(P<O.05);兩組胸片病變類型構(gòu)成比比較有顯著統(tǒng)計(jì)學(xué)差異(P<O.05),斑片狀陰影以中西醫(yī)結(jié)合組病例數(shù)多:中西醫(yī)結(jié)合組在第1時(shí)窗體溫明顯高于西醫(yī)治療組(P<0.01),雖從第2時(shí)窗開(kāi)始呈下降趨勢(shì),但仍高于西醫(yī)治療組(P<0.05),直至第4時(shí)窗兩組間比較無(wú)統(tǒng)計(jì)學(xué)差異(P>0.05);血?dú)夥治鯬aCO。(mmHg)變化在第4時(shí)窗組問(wèn)比較有統(tǒng)計(jì)學(xué)差異(P<O.05),中西醫(yī)結(jié)合組明顯低于西醫(yī)治療組;療程結(jié)束時(shí)中西醫(yī)結(jié)合組淋巴細(xì)胞絕對(duì)值的均值明顯高于西醫(yī)治療組(P<O.05);***強(qiáng)的松龍用量組間無(wú)顯著統(tǒng)計(jì)學(xué)差異(P>O.05),但其用量與年齡呈正相關(guān);兩組體溫(2Pm)重復(fù)測(cè)量的方差分析表明,分組及測(cè)量時(shí)點(diǎn)間比較有顯著的統(tǒng)計(jì)學(xué)差異(P<0.01);療程的協(xié)方差分析組問(wèn)比較有統(tǒng)計(jì)學(xué)差異(P<O.05),協(xié)變量年齡、***強(qiáng)的松龍總劑量有顯著統(tǒng)計(jì)學(xué)差異(P<O.05)。結(jié)論:中醫(yī)藥在SARS治療中確有療效。關(guān)鍵詞:中西醫(yī)結(jié)合,嚴(yán)重急性呼吸綜合征,臨床研究山西醫(yī)科大學(xué)碩士學(xué)位論文AretrospectiveclinicalstudyontreatmenttoSARSwithIntegratedChineseandWesternMedicineinShanXiprovinceAbstractObjective:essofthetreatmenttoSARSbyinterventionofChineseTraditionalMedicine(CTM)andIntegratedTraditionalChineseandWesternMedicine(ICWM).DocumentsandMethods:Databaseisbuiltupfrom430piecesofclinicalcaseofShanxiprovince.AfterdatainputbyuseofsoftwareEPIdata3.0,dataprocessincludingcheck,cleaningupandlockingupisdone.StatisticsanalysisismadebysoftwareSAS8.2.Inthearticle,thehistoricalcohortstudymethodisadoptedtomakeagreatvarietiesofresearchesonthefactorssuchasclinicalsymptoms,laboratorytestindex,X-raychestfilmetc.Results:ThedemographicdatabetweentwogroupsofITCWMandpureWesternMedicine(WM)parable(P>0.05).TheratioofpatientswhohaveotherdiseasesinITCWMgroupishigherthanthatofpureWMgroup(P<0.05).TheconditionofpatientsinITCWMgroupisheavierthanpureWMgroupwhenhospitalizing(P<0.05).TheabnormaltypesshowinginX.raychestfilmsoftwogroupshavesignificantdifferencesstatistically(P<O。05)withmoreshadowsoffleckinITCWMgroup.ThebodytemperatureinITCWMgroupisapparentlyhigherthanWMgroup(P<O.01)atfirsttimewindowalthoughdescendinginsecondtimewindowuntilhavingnostatisticaldifferencein4thtimewindow(P>0.05).PaC02analysishassignificantstatisticaldifferencein4thtimewindow(P<0.05)andITCWMgroupislowerthanWMgroupapparently.ellsinITCWMgrouparehigherthanWMgroupwhenthetreatmentendingup(p<O.05),heam'ountsofwhichhavepositivecorrelationwiththeage.AnalysisofvarianceontherepeatingbodytemperaturemeasuringbetweentwoTI山西醫(yī)科大學(xué)碩士學(xué)位論文groupsshowsthatthereissignificantstatisticaldifferencebetweenthegroupsandthepointsofmeasuringtime.Analysisofcovarianceontheperiodoftreatmentbetweentwogroupsshowsthatthereissignificantstatisticaldifferencebetweennotonlythegroupsbutalsotheageandthedosageofmethylprednisolone.Conclusion:CTMhascertaineffectiveresultsintreatmenttoSARSdisease.Keywords:IntegratedChineseandWestemMedicine,SevereAcuteRespiratorySyndrome(SARS),ClinicalResearch,Statisticalanalysis學(xué)位論文獨(dú)創(chuàng)性聲明本人宋曉慧聲明,所呈交的學(xué)位論文系在導(dǎo)師張劍宇、董聯(lián)玲教授指導(dǎo)下本文獨(dú)立完成的研究成果。文中任何引用他人的成果,均已做出明確標(biāo)注或得到許可。論文內(nèi)容未包含法律意義上已屬于他人的任何形式的研究成果,也不

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  本文關(guān)鍵詞：山西省中西醫(yī)結(jié)合治療SARS臨床回顧性研究，由筆耕文化傳播整理發(fā)布。