發(fā)布時(shí)間：2018-10-18 18:56

【摘要】：目的： 研究甲狀腺機(jī)能亢進(jìn)癥中醫(yī)六經(jīng)辨證分型與性別、年齡、甲狀腺腫大程度、突眼程度、合并癥、并發(fā)癥、FT3、TT3、FT4、TT4、TSH之間的關(guān)系,從而期望能夠?yàn)榧卓旱闹委�、預(yù)后及轉(zhuǎn)歸提供參考和幫助。 方法： 收集1990年1月1日至2013年3月31日期間于廣州中醫(yī)藥大學(xué)第一附屬醫(yī)院住院治療的甲狀腺機(jī)能亢進(jìn)患者共300例,制作調(diào)查表,填寫符合納入標(biāo)準(zhǔn)的病人相關(guān)信息,制定六經(jīng)辨證方案,對病人進(jìn)行辨證歸納。使用spssl1.5軟件進(jìn)行統(tǒng)計(jì)分析,計(jì)量資料符合正態(tài)分布的用t檢驗(yàn),不符合正態(tài)分布的用秩和檢驗(yàn)；計(jì)數(shù)資料采用卡方檢驗(yàn)。 結(jié)果： 在性別上,男性占130例,女性占170例,男女患者之間的比例為1：1.4；六經(jīng)分型陽證者女性居多,而陰證者以男性患者為主,陰陽寒熱錯(cuò)雜證男女患者人數(shù)相當(dāng),差異具有統(tǒng)計(jì)學(xué)意義(p0.01)。在年齡上,陽證、陰陽寒熱錯(cuò)雜證以60歲以下的患者為主,而60歲以上的患者多表現(xiàn)為陰證,差異具有統(tǒng)計(jì)學(xué)意義(p0.01)。合并糖尿病患者47例,占15.67%,陽證、陰證及陰陽寒熱錯(cuò)雜證患者中合并糖尿病的分別占14.28%、21.74%、13.10%,差異沒有統(tǒng)計(jì)學(xué)意義(p=0.2780.05)。合并重癥肌無力的患者有32例,占10.7%,陽證、陰證及陰陽寒熱錯(cuò)雜證患者中合并重癥肌無力的分別占6.80%,26.09%,3.57%,差異具有統(tǒng)計(jì)學(xué)意義(p0.01)。并發(fā)甲亢性心臟病的患者有102例,占34%,陽證、陰證及陰陽寒熱錯(cuò)雜證并發(fā)甲亢性心臟病的患者所占比例分別為42.18%,39.13%,15.48%,陽證所占的比例最大,差異具有統(tǒng)計(jì)學(xué)意義(p0.01)。合并突眼的患者有87例,占29%,陽證、陰證及陰陽寒熱錯(cuò)雜證患者中合并突眼率分別為41.50%、11.59%、21.43%,陽證患者所占比例最大,差異具有統(tǒng)計(jì)學(xué)意義(p0.01)。伴甲狀腺腫大的患者有175例,占58.33%,陽證、陰證及陰陽寒熱錯(cuò)雜證患者中伴甲狀腺腫大的分別為78.91%、15.94%、57.14%,陽證患者所占比例最大,腫大程度以工度腫大多見；陰陽寒熱錯(cuò)雜證患者次之,甲狀腺腫大程度以Ⅱ、Ⅲ度腫大為主；而陰證甲亢患者多數(shù)不伴有甲狀腺腫大,差異具有統(tǒng)計(jì)學(xué)意義(p0.01)。陽證、陰證及陰陽寒熱錯(cuò)雜證的TSH均較正常值偏低,差異不具統(tǒng)計(jì)學(xué)意義。三種證型TT3、FT3均較正常值偏高,差異不具統(tǒng)計(jì)學(xué)意義。三種證型TT4、FT4均較正常值偏高,但陰證TT4、FT4升高幅度不明顯,比陽證、陰陽寒熱錯(cuò)雜證低,且差異具有統(tǒng)計(jì)學(xué)意義(p0.05)。 結(jié)論： 甲狀腺機(jī)能亢進(jìn)癥六經(jīng)分型陽證者女性居多,而陰證者以男性患者為主,陰陽寒熱錯(cuò)雜證男女患者人數(shù)相當(dāng)；陽證、陰陽寒熱錯(cuò)雜證以60歲以下的患者為主,而60歲以上的患者多表現(xiàn)為陰證；甲亢合并重癥肌無力的患者以陰證為主；甲亢并發(fā)甲亢性心臟病患者多為陽證；甲亢合并突眼以陽證患者所占比例最大；甲狀腺腫大方面,陽證患者所占比例最大,腫大程度以Ⅰ度腫大多見,陰陽寒熱錯(cuò)雜證患者次之,甲狀腺腫大程度以Ⅱ、Ⅲ度腫大為主；甲亢屬陰證部分患者主要以TT3、FT3增高為主。
[Abstract]:Purpose: To study the relationship between syndrome differentiation type and sex, age, goiter degree, degree of treatment, complication, complication, FT3, TT3, FT4, TT4 and TSH in patients with hyperthyroidism Reference to treatment, prognosis and outcome of treatment, prognosis, and outcome and help Methods: 300 patients with hyperthyroidism were collected from January 1, 1990 to March 31, 2013 in the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine. Information and Development of Six meridians Based on Syndrome Differentiation By using spssl1. 5 software for statistical analysis, the measurement data is in accordance with the t-test of normal distribution, and it does not accord with the rank sum test of normal distribution.; count Results: There were 130 males and 170 females, and the proportion between male and female patients was 1: 1. 4; 6 were male and female. In contrast, the difference was statistically significant (P. 0.01). In age, the syndrome of yang-yang and yang-yang syndrome was dominated by patients under the age of 60 and more than 60 years old. There were 47 cases (15.67%) of patients with diabetes mellitus (15.67%), and 14. 28%, 21. 74%, 13. 10%, respectively, in the patients with diabetes mellitus (14.28%, 21. 74%, 13. 10%). There were 32 patients with myasthenia gravis, accounting for 10. 7% of the patients with myasthenia gravis, accounting for 6. 80%, 26. 09%, 3. 5, respectively. The percentage of patients with hyperthyroid heart disease was 42. 18%, 39. 13%, 15. 48%, and the proportion of positive syndrome was 42. 18%, 39. 13%, 15. 48% respectively. The results showed that there were 87 cases, 29%, 41. 59%, 21. 43% respectively, and the proportion of patients with positive syndrome were 41. 50%, 11. 59%, 21. 43%, respectively. There were 175 cases of patients with goiter, accounting for 58. 33% of patients with goiter, 78. 91%, 15.94%, 57. 14%, respectively. The number of patients with yin-yang and cold-heat syndrome is the second and the extent of goiter is II and 鈪，

本文編號：2280072