氧化釹和氟化釹粉塵對作業(yè)人員血液學(xué)指標(biāo)及炎性細(xì)胞因子表達(dá)的影響
發(fā)布時間:2019-06-25 19:00
【摘要】:隨機(jī)抽取某稀土廠接觸氧化釹、氟化釹粉塵的32名作業(yè)工人作為暴露組,不接塵的43名人員為對照組,采集靜脈血,檢測血液中釹及其化合物含量,血常規(guī)、血生化指標(biāo)及血清中炎性因子(IL-6、IL-10、TNF-α、CC16、SP-D)水平。暴露組血液中釹及其化合物濃度高于對照組,紅細(xì)胞均值(RBC)高于對照組,谷丙轉(zhuǎn)氨酶(ALT)、谷草轉(zhuǎn)氨酶(AST)高于對照組,血清中克細(xì)胞白介素6(IL-6)含量高于對照組,差異均有統(tǒng)計(jì)學(xué)意義(p0.05)。氧化釹、氟化釹粉塵經(jīng)呼吸道進(jìn)入人體,對作業(yè)人員肝臟、呼吸系統(tǒng)有影響。
[Abstract]:32 workers exposed to neodymium oxide and neodymium fluoride dust from a rare earth factory were randomly selected as exposure group and 43 workers without dust exposure as control group. Venous blood was collected to detect the content of neodymium and its compounds in blood, blood routine, blood biochemical indexes and serum inflammatory factor (IL-6,IL-10,TNF- 偽, CC16,SP-D) levels. The concentration of neodymium and its compounds in blood of exposed group was higher than that of control group, the mean (RBC) of erythrocyte was higher than that of control group, the (AST) of glutamic-pyruvic transaminase (ALT), glutamic oxaloacetic transaminase was higher than that of control group, and the content of IL-6 (IL-6) in serum was significantly higher than that of control group (p0.05). Neodymium oxide and neodymium fluoride dust enter the human body through respiratory tract, which has an impact on the liver and respiratory system of workers.
【作者單位】: 包頭醫(yī)學(xué)院公共衛(wèi)生學(xué)院;
【基金】:內(nèi)蒙古自然基金項(xiàng)目(2013MS1112)
【分類號】:R131
本文編號:2505924
[Abstract]:32 workers exposed to neodymium oxide and neodymium fluoride dust from a rare earth factory were randomly selected as exposure group and 43 workers without dust exposure as control group. Venous blood was collected to detect the content of neodymium and its compounds in blood, blood routine, blood biochemical indexes and serum inflammatory factor (IL-6,IL-10,TNF- 偽, CC16,SP-D) levels. The concentration of neodymium and its compounds in blood of exposed group was higher than that of control group, the mean (RBC) of erythrocyte was higher than that of control group, the (AST) of glutamic-pyruvic transaminase (ALT), glutamic oxaloacetic transaminase was higher than that of control group, and the content of IL-6 (IL-6) in serum was significantly higher than that of control group (p0.05). Neodymium oxide and neodymium fluoride dust enter the human body through respiratory tract, which has an impact on the liver and respiratory system of workers.
【作者單位】: 包頭醫(yī)學(xué)院公共衛(wèi)生學(xué)院;
【基金】:內(nèi)蒙古自然基金項(xiàng)目(2013MS1112)
【分類號】:R131
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【相似文獻(xiàn)】
相關(guān)期刊論文 前1條
1 楊艷霞;張翼翔;陰海靜;楊寧;;稀土氟化釹微粒致大鼠肺損傷的實(shí)驗(yàn)研究[J];包頭醫(yī)學(xué)院學(xué)報(bào);2014年01期
,本文編號:2505924
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