【摘要】：隨機(jī)抽取某稀土廠接觸氧化釹、氟化釹粉塵的32名作業(yè)工人作為暴露組,不接塵的43名人員為對(duì)照組,采集靜脈血,檢測(cè)血液中釹及其化合物含量,血常規(guī)、血生化指標(biāo)及血清中炎性因子(IL-6、IL-10、TNF-α、CC16、SP-D)水平。暴露組血液中釹及其化合物濃度高于對(duì)照組,紅細(xì)胞均值(RBC)高于對(duì)照組,谷丙轉(zhuǎn)氨酶(ALT)、谷草轉(zhuǎn)氨酶(AST)高于對(duì)照組,血清中克細(xì)胞白介素6(IL-6)含量高于對(duì)照組,差異均有統(tǒng)計(jì)學(xué)意義(p0.05)。氧化釹、氟化釹粉塵經(jīng)呼吸道進(jìn)入人體,對(duì)作業(yè)人員肝臟、呼吸系統(tǒng)有影響。
[Abstract]:32 workers exposed to neodymium oxide and neodymium fluoride dust from a rare earth factory were randomly selected as exposure group and 43 workers without dust exposure as control group. Venous blood was collected to detect the content of neodymium and its compounds in blood, blood routine, blood biochemical indexes and serum inflammatory factor (IL-6,IL-10,TNF- 偽, CC16,SP-D) levels. The concentration of neodymium and its compounds in blood of exposed group was higher than that of control group, the mean (RBC) of erythrocyte was higher than that of control group, the (AST) of glutamic-pyruvic transaminase (ALT), glutamic oxaloacetic transaminase was higher than that of control group, and the content of IL-6 (IL-6) in serum was significantly higher than that of control group (p0.05). Neodymium oxide and neodymium fluoride dust enter the human body through respiratory tract, which has an impact on the liver and respiratory system of workers.
【作者單位】： 包頭醫(yī)學(xué)院公共衛(wèi)生學(xué)院;
【基金】：內(nèi)蒙古自然基金項(xiàng)目(2013MS1112)
【分類號(hào)】：R131

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 王輝;王瑞;;矽肺早期診斷的生物標(biāo)志物CC16和SP-D[J];中國(guó)工業(yè)醫(yī)學(xué)雜志;2012年04期

【二級(jí)參考文獻(xiàn)】

相關(guān)期刊論文 前3條

1 章曉紅;Clara細(xì)胞蛋白與肺部疾病[J];國(guó)外醫(yī)學(xué).呼吸系統(tǒng)分冊(cè);2002年01期

2 聶小蒙;Clara細(xì)胞蛋白-CC16[J];國(guó)外醫(yī)學(xué).呼吸系統(tǒng)分冊(cè);2004年02期

3 陳敏;王世鑫;;矽肺發(fā)病機(jī)制的研究現(xiàn)狀[J];武警醫(yī)學(xué)院學(xué)報(bào);2005年06期

【相似文獻(xiàn)】

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1 楊艷霞;張翼翔;陰海靜;楊寧;;稀土氟化釹微粒致大鼠肺損傷的實(shí)驗(yàn)研究[J];包頭醫(yī)學(xué)院學(xué)報(bào);2014年01期

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本文編號(hào)：2505924