職業(yè)接觸噪聲人群職業(yè)緊張與皮質(zhì)醇和熱休克蛋白70水平研究
發(fā)布時間：2018-11-21 09:42
【摘要】：目的：研究職業(yè)接觸噪聲人群職業(yè)緊張現(xiàn)狀及其影響因素,探討噪聲暴露和職業(yè)緊張對血清中皮質(zhì)醇和熱休克蛋白70(HSP70)的影響,探討皮質(zhì)醇和HSP70作為職業(yè)應(yīng)激生理學(xué)評價指標(biāo)的應(yīng)用價值,為提出有效干預(yù)措施,控制職業(yè)接觸噪聲人群職業(yè)緊張水平,保障勞動者健康提供依據(jù)。 方法：選擇廣東省2間以噪聲危害為主的企業(yè)進(jìn)行職業(yè)衛(wèi)生現(xiàn)場調(diào)查和職業(yè)病危害因素檢測,了解調(diào)查目標(biāo)人群的職業(yè)健康狀況；采用職業(yè)緊張量表(OSI-R)對599名噪聲組工人和270名對照組工人進(jìn)行問卷調(diào)查。從噪聲組和對照組工人中,按不同職業(yè)緊張反應(yīng)級別,分別抽取2組人員進(jìn)行血清皮質(zhì)醇和HSP70含量的測定。 結(jié)果：①4.67%的噪聲組工人感到高度職業(yè)任務(wù)過重,30.21%的噪聲組工人員感到中度職業(yè)任務(wù)過重,63.61%的噪聲組工人感到職業(yè)任務(wù)適度,1.51%感到職業(yè)任務(wù)缺乏；8.18%的噪聲組工人有高度職業(yè)緊張反應(yīng),28.05%的噪聲組工人有中度職業(yè)緊張反應(yīng),62.10%噪聲組工人職業(yè)緊張反應(yīng)適度,1.67%的噪聲組工人職業(yè)緊張反應(yīng)缺乏；20.37%噪聲組工人有很強(qiáng)的應(yīng)對資源,66.44%噪聲組工人有適度的應(yīng)對資源,10.52%噪聲組工人中度缺乏應(yīng)對資源,2.67%噪聲組工人高度缺乏應(yīng)對資源。②噪聲組工人職業(yè)任務(wù)和職業(yè)緊張反應(yīng)問卷及其大部分子項(xiàng)得分高于國內(nèi)常模水平,工作環(huán)境和職業(yè)緊張反應(yīng)問卷及其子項(xiàng)(除業(yè)務(wù)緊張反應(yīng)和心理緊張反應(yīng)外)得分高于對照組工人,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。③接觸不同噪聲水平的噪聲組工人隨著接觸噪聲水平的升高職業(yè)任務(wù)問卷和職業(yè)緊張反應(yīng)問卷及其各子項(xiàng)有升高的趨勢,應(yīng)對資源問卷(PRQ)及其各子項(xiàng)有降低的趨勢,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。④噪聲組工人職業(yè)緊張反應(yīng)問卷及其各子項(xiàng)與職業(yè)任務(wù)問卷及其各子項(xiàng)呈正相關(guān)關(guān)系,與應(yīng)對資源問卷及其各子項(xiàng)呈負(fù)相關(guān)關(guān)系。⑤影響噪聲組工人職業(yè)緊張反應(yīng)的因素主要有責(zé)任感、工作環(huán)境、社會支持、任務(wù)過重、理性處事、任務(wù)沖突、任務(wù)模糊和性別。⑥具有高度職業(yè)緊張反應(yīng)和中度職業(yè)緊張反應(yīng)的噪聲組工人的血清皮質(zhì)醇和HSP70水平比具有適度職業(yè)緊張反應(yīng)的噪聲組工人更高,差異有統(tǒng)計(jì)學(xué)意義(P0.05)；在中度職業(yè)緊張反應(yīng)組和適度職業(yè)緊張反應(yīng)組中,噪聲組比對照組工人具有更高的血清皮質(zhì)醇和HSP70水平,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。 結(jié)論：①接觸噪聲職業(yè)人群的職業(yè)緊張水平較高,其職業(yè)任務(wù)、職業(yè)緊張反應(yīng)水平均高于用國內(nèi)一般人群所建的常模；工作環(huán)境中的噪聲影響是導(dǎo)致噪聲組與對照組工人之間職業(yè)任務(wù)和職業(yè)緊張反應(yīng)差異的主要原因,可使噪聲組工人產(chǎn)生更重的職業(yè)任務(wù)和更強(qiáng)烈的職業(yè)緊張反應(yīng)。②職業(yè)緊張反應(yīng)和噪聲可作為人群血清皮質(zhì)醇和HSP70水平的重要影響因素,噪聲暴露和超出適度范圍的職業(yè)緊張反應(yīng)可導(dǎo)致血清皮質(zhì)醇和HSP70水平的升高。
[Abstract]:Objective: to study the status quo of occupational stress and its influencing factors in occupational exposed people, and to explore the effects of noise exposure and occupational stress on serum cortisol and heat shock protein 70 (HSP70). To explore the application value of cortisol and HSP70 as the physiological evaluation index of occupational stress, to provide the basis for effective intervention measures to control occupational stress level of occupational noise population and to ensure the health of workers. Methods: two enterprises with noise hazard were selected to investigate occupational health and occupational disease hazard factors in order to understand the occupational health status of the target population. Occupational stress scale (OSI-R) was used to investigate 599 workers in noise group and 270 workers in control group. The levels of serum cortisol and HSP70 were measured in two groups of workers in noise group and control group according to different levels of occupational stress reaction. Results: 14.67% of the noise workers felt that the high occupational tasks were overweight, 30.21% of the noise workers felt the moderate occupational tasks, 63.61% of the noise workers felt that the occupational tasks were moderate. 1.51% felt lack of professional tasks; 8.18% workers in noise group had high occupational stress reaction, 28.05% workers in noise group had moderate occupational stress reaction, 62.10% workers in noise group had moderate occupational stress reaction, and 1.67% workers in noise group had lack of occupational stress reaction. 20.37% of the workers in the noise group had strong coping resources, 66.44% of the workers in the noise group had moderate response resources, 10.52% of the workers in the noise group had moderate lack of coping resources. 2.67% of the workers in the noise group were highly deficient in coping resources. 2 the scores of occupational task and occupational stress response questionnaire and most of their subitems in the noise group were higher than those in the domestic norm. The scores of work environment and occupational stress response questionnaire and their sub-items (except business stress response and psychological stress response) were higher than those of the control group. The difference was statistically significant (P0.05). 3 the occupational task questionnaire, occupational stress response questionnaire and their sub-items of workers exposed to different noise levels increased with the increase of exposure noise level. The (PRQ) and its subitems of coping resource questionnaire decreased, and the difference was statistically significant (P0.05). 4 the occupational stress response questionnaire and its sub-items in noise group were positively correlated with the occupational task questionnaire and their sub-items. The factors influencing occupational stress response of workers in noise group were responsibility, work environment, social support, task overload, rational handling, task conflict, etc. The serum cortisol and HSP70 levels in the noise group with high and moderate occupational stress responses were higher than those in the noise group with moderate occupational stress response. The difference was statistically significant (P0.05). In the moderate occupational stress response group and moderate occupational stress response group, the noise group had higher serum cortisol and HSP70 levels than the control group, the difference was statistically significant (P0.05). Conclusion: (1) the occupational stress level of the occupational population exposed to noise is higher than that of the norm established by the general population in China. The effect of noise in the working environment was the main reason for the difference of occupational task and occupational stress reaction between the noise group and the control group. Occupational stress response and noise may be important influencing factors of serum cortisol and HSP70 levels. Noise exposure and occupational stress over a moderate range can lead to elevated serum cortisol and HSP70 levels.
【學(xué)位授予單位】：山西醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R131
本文編號：2346595
[Abstract]:Objective: to study the status quo of occupational stress and its influencing factors in occupational exposed people, and to explore the effects of noise exposure and occupational stress on serum cortisol and heat shock protein 70 (HSP70). To explore the application value of cortisol and HSP70 as the physiological evaluation index of occupational stress, to provide the basis for effective intervention measures to control occupational stress level of occupational noise population and to ensure the health of workers. Methods: two enterprises with noise hazard were selected to investigate occupational health and occupational disease hazard factors in order to understand the occupational health status of the target population. Occupational stress scale (OSI-R) was used to investigate 599 workers in noise group and 270 workers in control group. The levels of serum cortisol and HSP70 were measured in two groups of workers in noise group and control group according to different levels of occupational stress reaction. Results: 14.67% of the noise workers felt that the high occupational tasks were overweight, 30.21% of the noise workers felt the moderate occupational tasks, 63.61% of the noise workers felt that the occupational tasks were moderate. 1.51% felt lack of professional tasks; 8.18% workers in noise group had high occupational stress reaction, 28.05% workers in noise group had moderate occupational stress reaction, 62.10% workers in noise group had moderate occupational stress reaction, and 1.67% workers in noise group had lack of occupational stress reaction. 20.37% of the workers in the noise group had strong coping resources, 66.44% of the workers in the noise group had moderate response resources, 10.52% of the workers in the noise group had moderate lack of coping resources. 2.67% of the workers in the noise group were highly deficient in coping resources. 2 the scores of occupational task and occupational stress response questionnaire and most of their subitems in the noise group were higher than those in the domestic norm. The scores of work environment and occupational stress response questionnaire and their sub-items (except business stress response and psychological stress response) were higher than those of the control group. The difference was statistically significant (P0.05). 3 the occupational task questionnaire, occupational stress response questionnaire and their sub-items of workers exposed to different noise levels increased with the increase of exposure noise level. The (PRQ) and its subitems of coping resource questionnaire decreased, and the difference was statistically significant (P0.05). 4 the occupational stress response questionnaire and its sub-items in noise group were positively correlated with the occupational task questionnaire and their sub-items. The factors influencing occupational stress response of workers in noise group were responsibility, work environment, social support, task overload, rational handling, task conflict, etc. The serum cortisol and HSP70 levels in the noise group with high and moderate occupational stress responses were higher than those in the noise group with moderate occupational stress response. The difference was statistically significant (P0.05). In the moderate occupational stress response group and moderate occupational stress response group, the noise group had higher serum cortisol and HSP70 levels than the control group, the difference was statistically significant (P0.05). Conclusion: (1) the occupational stress level of the occupational population exposed to noise is higher than that of the norm established by the general population in China. The effect of noise in the working environment was the main reason for the difference of occupational task and occupational stress reaction between the noise group and the control group. Occupational stress response and noise may be important influencing factors of serum cortisol and HSP70 levels. Noise exposure and occupational stress over a moderate range can lead to elevated serum cortisol and HSP70 levels.
【學(xué)位授予單位】：山西醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R131
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