【摘要】：目的分析一起�？�30型病毒引起的學校病毒性腦膜炎暴發(fā)疫情的流行病學特征及可能的危險因素,為制定預防控制措施提供科學依據。方法采用現(xiàn)場流行病學調查收集病例情況和可能的傳播途徑等信息,采集相關標本進行PCR核酸檢測,采用1∶2匹配病例對照研究方法探索可能的危險因素。結果共報告103例病例,罹患率4.6%,男女性別比2.03∶1,病例主要集中在三年級(72/103)。病例咽拭子、肛拭子腸道通用病毒RT-PCR檢測81.5%(22/27)為陽性,其中7例PCR序列分析確定為埃可30型病毒。結論此次病毒性腦膜炎暴發(fā)疫情是由埃可30型病毒引起的,加強學校傳染病防控知識培訓、衛(wèi)生宣教、晨檢、因病缺課病因追查、登記和報告、病例隔離和疫點消毒工作對控制疫情十分重要。
[Abstract]:Objective to analyze the epidemiological characteristics and possible risk factors of a school viral meningitis outbreak caused by Echo 30 virus, and to provide scientific basis for making prevention and control measures. Methods the information of cases and possible ways of transmission were collected by field epidemiological investigation. PCR nucleic acid was detected in relevant samples. The 1:2 matched case-control study was used to explore the possible risk factors. Results 103 cases were reported, the attack rate was 4.6%, the ratio of male to female was 2.03: 1. The cases were mainly in the third grade (72 / 103). In throat swabs and anal swabs, 81.5% (22 / 27) of the cases were positive for enterovirus RT-PCR, among which 7 cases were identified as EK30 virus by PCR sequence analysis. Conclusion the outbreak of viral meningitis is caused by EK30 virus. We should strengthen the knowledge training of infectious disease prevention and control, health education, morning examination, tracing, registration and report of the disease absent from school. Isolation of cases and disinfection of epidemic spots are very important for the control of epidemic situation.
【作者單位】： 江陰市疾病預防控制中心;江陰市徐霞客醫(yī)院;
【分類號】：R725.1;R181.3

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