2011-2015年河北省手足口病流行特征及病原特征分析
發(fā)布時間:2018-04-10 19:50
本文選題:手足口病 + 聚類分析; 參考:《中華疾病控制雜志》2017年02期
【摘要】:目的分析河北省手足口病(hand foot and mouth disease,HFMD)的流行特征及病原學(xué)構(gòu)成,為手足口病的防控提供科學(xué)依據(jù)。方法利用描述流行病學(xué)方法對河北省2011-2015年疾病監(jiān)測信息報告系統(tǒng)上報的手足口病病例和實驗室檢測結(jié)果進(jìn)行統(tǒng)計分析。結(jié)果 2011-2015年累計報告手足口病病例349 113例,年均發(fā)病率為95.91/10萬,其中2012年和2014年報告發(fā)病率最高,呈現(xiàn)隔年高水平流行的現(xiàn)象。高發(fā)期集中在5~7月,10~12月間又出現(xiàn)一個次高峰或"拖尾"峰,患者主要為≤5歲兒童,尤其以1~3歲組嬰幼兒為主。各地區(qū)發(fā)病水平存在差異,以發(fā)病率和重癥率為分類指標(biāo)對各地市進(jìn)行聚類分析和賦值評價,得到重點防控地區(qū)為廊坊市、滄州市、衡水市、石家莊市、保定市和承德市。不同年份病原構(gòu)成亦不同,在2013年和2015年其他腸道病毒分別取代柯薩奇病毒A組16型(coxsachievirus A16,Cox A16)、腸道病毒71型(enterovirus 71,EV71)成為當(dāng)年主要病原體,構(gòu)成比高達(dá)44.89%和66.23%。結(jié)論河北省手足口病呈現(xiàn)明顯的季節(jié)、人群以及一定的地區(qū)分布規(guī)律,應(yīng)進(jìn)一步關(guān)注手足口病病原譜的變化,加強(qiáng)重點地區(qū)防控。
[Abstract]:Objective to analyze the epidemic characteristics and etiological composition of hand, foot and mouth disease (HFMD) of hand, foot and mouth disease (foot and mouth) in Hebei Province, so as to provide scientific basis for the prevention and control of hand, foot and mouth disease.Methods descriptive epidemiology was used to analyze the HFMD cases and laboratory results reported by the disease surveillance information system from 2011 to 2015 in Hebei province.Results A total of 349,113 HFMD cases were reported in 2011-2015, with an average annual incidence of 95.91 / 100000, among which the highest incidence was reported in 2012 and 2014.The period of high incidence was from May to July, from October to December, there was a sub-peak or "tail dragging" peak. The patients were mainly children 鈮,
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