本文選題：腸道腺病毒 + 嬰幼兒腹瀉�。� 參考：《醫(yī)學(xué)動(dòng)物防制》2016年12期

【摘要】：目的研究盧龍地區(qū)嬰幼兒腹瀉病例腸道腺病毒流行病學(xué)特點(diǎn)。方法收集2010-2014年盧龍縣兒童醫(yī)院及婦幼保健院5歲以下住院患兒腹瀉標(biāo)本,采用PCR法檢測(cè)腸道腺病毒。結(jié)果 1 880份腹瀉標(biāo)本檢測(cè)出腸道腺病毒陽(yáng)性標(biāo)本119份,總陽(yáng)性檢出率為6.33%;男女患兒檢出率分別為7.29%和4.81%,差異有統(tǒng)計(jì)學(xué)意義(χ2=4.59,P0.05);36月齡患兒占總陽(yáng)性數(shù)的97.48%,患兒中位年齡為16月齡(11~24月齡),各年齡組間檢出率差異無(wú)統(tǒng)計(jì)學(xué)意義(χ2=4.99,P0.05);2010-2014年累計(jì)檢出腸道腺病毒陽(yáng)性標(biāo)本不同月份間累計(jì)年均檢出率差異有統(tǒng)計(jì)學(xué)意義(χ2=53.63,P0.05),但腸道腺病毒感染僅在2010年10月~次年4月呈現(xiàn)一個(gè)明顯的寒冷季節(jié)高發(fā)的流行趨勢(shì),從2012年開(kāi)始無(wú)明顯季節(jié)差異。結(jié)論腸道腺病毒是盧龍地區(qū)嬰幼兒腹瀉的重要病原,男患兒陽(yáng)性檢出率高于女患兒,可能與男童暴露和感染機(jī)會(huì)更多有關(guān)。
[Abstract]:Objective to study the epidemiological characteristics of intestinal adenovirus in infants with diarrhea in Lulong area.Methods the diarrhea samples of children under 5 years old in Lulong Children's Hospital and Maternal and Child Health Hospital from 2010 to 2014 were collected and detected by PCR method.Results 119 positive specimens of adenovirus were detected in 1 880 diarrhea specimens.The total positive rate was 6.33 and the positive rate was 7.29% and 4.81 in male and female, respectively. The difference was statistically significant (蠂 ~ 2 / 4.59%, P 0.05 / 36 months old accounted for 97.48% of the total positive rate, and the median age was 1124 months old / 16 months old). There was no significant difference in detection rate among different age groups.The cumulative positive rate of intestinal adenovirus was significantly different in different months from 2010 to 2014 (蠂 2 + 53.63%, P 0.05%). However, the prevalence of intestinal adenovirus infection was only high in cold season from October 2010 to April of the following year.There has been no significant seasonal variation since 2012.Conclusion intestinal adenovirus is an important pathogen of infantile diarrhea in Lulong area. The positive rate of intestinal adenovirus in male children is higher than that in female children, which may be related to the exposure of boys and the chance of infection.
【作者單位】： 河北省疾病預(yù)防控制中心;
【基金】：河北科技計(jì)劃項(xiàng)目(14277761D)
【分類(lèi)號(hào)】：R725.1;R181.3

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