本文選題：雙酚A　切入點(diǎn)：記憶功能　出處：《現(xiàn)代預(yù)防醫(yī)學(xué)》2017年16期 　論文類型：期刊論文

【摘要】：雙酚A通過塑料食品包裝材料遷移到食品中,從而被人體吸收,其可誘發(fā)多種疾病,對人體健康產(chǎn)生危害。該食品安全問題已引起國內(nèi)外廣泛關(guān)注,諸多研究表明雙酚A可誘發(fā)腫瘤、影響生育等疾病,近年來又發(fā)現(xiàn)雙酚A對記憶能力也有較大負(fù)面影響。本文從信號通路、突觸可塑性與結(jié)構(gòu)修飾、表觀遺傳修飾的改變等方面闡述雙酚A對動(dòng)物海馬區(qū)記憶功能的影響及其機(jī)制方面的研究進(jìn)行綜述,以引起廣大相關(guān)研究者的重視,并為食品安全防范提供科學(xué)依據(jù)。
[Abstract]:Bisphenol A (BPA) is absorbed by the human body through the migration of plastic food packaging materials, which can induce many diseases and harm human health. This food safety problem has aroused widespread concern at home and abroad. Many studies have shown that bisphenol A can induce tumors, affect fertility and other diseases. In recent years, it has been found that bisphenol A also has a negative effect on memory. The effects of bisphenol A on the memory function of hippocampal area of animals and its mechanism were reviewed in order to attract the attention of relevant researchers and provide scientific basis for food safety prevention.
【作者單位】： 哈爾濱醫(yī)科大學(xué)藥學(xué)院藥物化學(xué)與天然藥物化學(xué)教研室;
【基金】：黑龍江省大學(xué)生創(chuàng)新項(xiàng)目基金[項(xiàng)目編號201610226069] 哈爾濱市應(yīng)用技術(shù)研究與開發(fā)項(xiàng)目基金[項(xiàng)目編號2016RAQXJ184]
【分類號】：R114
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本文編號：1643903