本文選題：柯薩奇腸道病毒A　切入點：手足口病　出處：《現(xiàn)代預(yù)防醫(yī)學(xué)》2017年05期 　論文類型：期刊論文

【摘要】：目的了解保定市COXA6型手足口病伴脫甲癥病例的流行病學(xué)特征及相關(guān)因素,為制定防控措施提供科學(xué)依據(jù)。方法采用熒光定量RT-PCR法對2015年1月至2016年5月保定市哨點醫(yī)院采集的手足口病病例咽拭子標本進行柯薩奇病毒A6型核酸檢測,篩選COXA6型手足口病,并按是否伴有脫甲分為脫甲組和未脫甲組,利用檢驗對兩組人群分布、臨床特征、皮損特征及衛(wèi)生行為情況進行對比分析,并利用Logistic回歸分析COXA6型手足口病伴脫甲癥的相關(guān)因素。結(jié)果保定市COXA6型手足口病伴脫甲癥病例主要集中在5歲以內(nèi),以1~2歲患兒所占比例最高且男性多于女性。既往有皮膚過敏史(OR=5.230)、皮疹在指或趾甲周圍分布(OR=10.599)和皮疹面積大于5%(OR=10.776)為COXA6型手足口病伴脫甲癥病例的危險因素。結(jié)論對于既往有皮膚過敏史、皮疹在指或趾甲周圍分布以及皮疹面積大于5%的COXA6型手足口病患兒要加強重視,以防其脫甲癥的發(fā)生。同時在COXA6型手足口病流行期間加強的衛(wèi)生防范措施,不會導(dǎo)致脫甲癥的發(fā)生。
[Abstract]:Objective to investigate the epidemiological characteristics and related factors of COXA6's hand, foot and mouth disease with dethyroidism in Baoding City. Methods the throat swabs of hand-foot-mouth disease cases collected from January 2015 to May 2016 in Baoding City were detected by fluorescence quantitative RT-PCR method for Coxsackie virus A6 nucleic acid. COXA6 type hand-foot-mouth disease was screened and divided into two groups according to whether it was accompanied by de-armor or not. The distribution, clinical characteristics, skin lesions and hygienic behavior of the two groups were compared and analyzed by means of test. Logistic regression analysis was used to analyze the related factors of COXA6 hand, foot and mouth disease with dethyroidism. Results the cases of COXA6 hand foot and mouth disease with dethyroidism in Baoding City were mainly within 5 years old. The proportion of children aged 1 to 2 years was the highest and the proportion of males was higher than that of females. The history of skin allergy was 5.230%, and the skin rash was distributed around the fingers or toenails. (10.599) and the area of rash was larger than 50.776) as the risk factors of COXA6 hand, foot and mouth disease with dethyroidism. Had a history of skin allergies, Attention should be paid to the distribution of skin rash around finger or toenail and the area of skin rash larger than 5% in children with hand, foot and mouth disease of COXA6 type, so as to prevent the occurrence of dethyroidism. Meanwhile, the health precautions should be strengthened during the epidemic period of COXA6 hand, foot and mouth disease. It does not cause dethyroidism.
【作者單位】： 保定市疾病預(yù)防控制中心;唐縣人民醫(yī)院;保定市第一中醫(yī)院;
【基金】：保定市科學(xué)技術(shù)研究與發(fā)展指導(dǎo)計劃項目,項目編號為15ZF088
【分類號】：R725.1;R181.3
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本文編號：1562895