本文選題：飲水　切入點(diǎn)：礦物質(zhì)　出處：《第三軍醫(yī)大學(xué)學(xué)報(bào)》2017年11期 　論文類型：期刊論文

【摘要】：目的比較礦物質(zhì)水平差別顯著的3種飲水對大鼠繁殖能力和子代發(fā)育的影響。方法將45只雄性和90只雌性斷乳SD大鼠按隨機(jī)數(shù)字表法分為3組(雌雄比為2∶1),分別飲用A水[溶解性總固體(total dissolved solids,TDS)為1.2 mg/L]、B水(TDS:87.2 mg/L)以及經(jīng)凈水器(活性炭濾芯)處理自來水后得到的C水(TDS:291.0 mg/L),連續(xù)3代。逐代比較親代繁殖指標(biāo)和子代發(fā)育指標(biāo)。結(jié)果親3代的繁殖指標(biāo)3組間均未見統(tǒng)計(jì)學(xué)差異。A水組仔鼠出生后4 d存活率至F3代時(shí)明顯低于其他2組。而C水組仔鼠出生后4 d存活率不僅在F1代時(shí)顯著高于B水組(P0.01),還在F3代時(shí)顯著高于其他2組,該組在F1代時(shí)記憶能力也有高于其他2組的趨勢。結(jié)論多代連續(xù)飲用礦物質(zhì)極低的飲水對大鼠繁殖能力影響不明顯,但低礦水對子代早期發(fā)育水平可能有不利影響。對于大鼠出生后的早期生長階段,飲用衛(wèi)生學(xué)上安全且富含礦物質(zhì)的飲水將對其發(fā)育更為有利。
[Abstract]:Objective to compare the effects of three kinds of drinking water with different mineral levels on reproductive ability and offspring development of rats. Methods 45 male and 90 female weaned SD rats were randomly divided into 3 groups (male to female = 2: 1). Drinking A water (total dissolved dissolved solidsm tds = 1.2 mg/L) and drinking water TDs: 87.2 mg / L) and C water TDS: 291.0 mg / L 路L ~ (-1) after treated with water by water purifier (activated carbon filter) were obtained for three consecutive generations. The reproductive index of parents and the development index of offspring were compared generation by generation. There was no significant difference in reproductive indices among the three groups. The survival rate of 4 days after birth in water group was significantly lower than that in the other two groups, but the survival rate in C water group was significantly higher than that in F1 generation. B water group was significantly higher than the other two groups in F3 generation. The memory ability of the group in F1 generation was also higher than that of the other two groups. Conclusion drinking water with very low mineral content for multiple generations has no obvious effect on the reproductive ability of rats. However, low mineral water may have an adverse effect on the early development of offspring, and drinking safe and mineral-rich drinking water will be more beneficial to the development of rats in the early growth stage after birth.
【作者單位】： 第三軍醫(yī)大學(xué)軍事預(yù)防醫(yī)學(xué)院軍隊(duì)環(huán)境衛(wèi)生學(xué)教研室;
【基金】：國家自然科學(xué)基金青年科學(xué)基金(81001234) 重慶市衛(wèi)生局醫(yī)學(xué)科研項(xiàng)目(2012-2-447)~~
【分類號】：R123

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