本文關(guān)鍵詞：中國(guó)母乳中低聚糖組分及含量變化——以中國(guó)廣東江門地區(qū)為例　出處：《食品科學(xué)》2017年18期 　論文類型：期刊論文

  更多相關(guān)文章： 高效陰離子色譜 母乳低聚糖 分泌型母乳 非分泌型母乳

【摘要】：密集收取22位中國(guó)母親共163個(gè)母乳樣品,采用高效陰離子色譜法監(jiān)測(cè)在不同泌乳期中22種母乳低聚糖(human milk oligosaccharides,HMOs)的組成和含量變化。結(jié)果表明,15種中性低聚糖含量在泌乳初期(初乳)達(dá)到最高值后逐漸減少(成熟乳),但是3-巖藻糖乳糖的含量在整個(gè)取樣階段均在持續(xù)增加。6種酸性低聚糖在泌乳初期穩(wěn)定但后期隨時(shí)間延長(zhǎng)逐漸減少,其中唾液酸化-乳糖-N-四糖a只在部分樣本中檢出。基于Lewis血型類型,可將母親分為分泌型組和非分泌型組。分泌型母親的母乳中富含α-1-2-L-巖藻糖基化低聚糖(如2’-巖藻糖乳糖、乳酰-N-巖藻五糖Ⅰ、二巖藻糖基乳糖、乳酰-N-二巖藻六糖Ⅰ)。在分泌型與非分泌型母乳中,α-1-2-L-巖藻糖基化低聚糖的質(zhì)量濃度范圍分別為1 211~7 272 mg/L和100~920 mg/L;然而α-1-3/4-L-巖藻糖基化低聚糖(如乳酰-N-二巖藻六糖Ⅱ、乳糖-N-二巖藻糖基-八糖、3-巖藻糖乳糖、乳酰-N-巖藻五糖Ⅱ)的質(zhì)量濃度范圍則分別為181~2 722 mg/L和476~4 931 mg/L�？傮w表明,分泌型和非分泌型母親在泌乳期內(nèi)的HMOs的組成和含量均在不斷變化且差異明顯。
[Abstract]:A total of 163 breast milk samples were collected from 22 Chinese mothers. High performance anion chromatography was used to detect 22 kinds of oligosaccharides milk oligosaccharides in different lactation periods. The results showed that the content of 15 neutral oligosaccharides decreased gradually at the beginning of lactation (colostrum) after reaching the highest value (mature milk). However, the content of 3-fucose lactose continued to increase in the whole sampling stage. 6 kinds of acidic oligosaccharides were stable in the early stage of lactation, but decreased gradually with the extension of time. Saliva acidified lactose-N- tetraccharide a was only detected in some samples based on the type of Lewis blood group. Mothers can be divided into secretory group and non-secretory group. Secretory mothers' breast milk is rich in 偽 -1-2-L-fucose oligosaccharides (such as 2-fucose lactose, lactoyl-N-fucose 鈪，

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