【摘要】：目的應(yīng)用多焦視網(wǎng)膜電流圖(mfERG)評價雷珠單抗治療年齡相關(guān)性黃斑變性(AMD)療效的價值。方法 AMD患者31例(31眼)接受玻璃體腔注射雷珠單抗治療,每月1次,共3次。比較治療前后患眼mfERG檢測中1-5環(huán)反應(yīng)振幅、潛伏期及最佳矯正視力的變化。結(jié)果治療后,患眼mfERG反應(yīng)振幅1、2環(huán)高于治療前(P0.01),反應(yīng)潛伏期1-5環(huán)均有降低(P0.05或P0.01)。結(jié)論 mfERG能明確顯示雷珠單抗治療AMD能有效改善視網(wǎng)膜的生理功能。
[Abstract]:Objective to evaluate the efficacy of razumab in the treatment of age-related macular degeneration (AMD) by multifocal electroretinal electrography (mfERG). Methods 31 patients (31 eyes) with AMD were treated with vitreous injection of rapezumab once a month for 3 times. The changes of amplitude, latency and best corrected visual acuity of 1 鈮，

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