【摘要】：【目的】為了評估阻塞性睡眠呼吸暫停低通氣綜合征(OSAHS)對新疆維吾爾族聽覺功能的影響,探討其損害部位及特點�！痉椒ā�70例維吾爾族成人經(jīng)多導(dǎo)睡眠監(jiān)測系統(tǒng)(PSG)檢查分為輕、中、重組OSAHS患者,選取35例維吾爾族健康成人為對照組。所有研究對象分別進行畸變產(chǎn)物耳聲發(fā)射(DPOAE)及聽性腦干反應(yīng)(ABR)檢測及分析,通過比較DPOAE的反應(yīng)幅值及ABR的各波潛伏期和波間期變化評估聽覺功能損害情況�！窘Y(jié)果】OSAHS患者DPOAE各頻率(750~8 000 Hz)的反應(yīng)幅值較對照組降低,差異有統(tǒng)計學(xué)意義(P0.05)。經(jīng)ABR檢測,輕中度OSAHS組與對照相比,波Ⅰ、Ⅲ、Ⅴ潛伏期及Ⅰ-Ⅲ、Ⅰ-Ⅴ波間期的延長,差異有統(tǒng)計學(xué)意義(P0.05);重度OSAHS組的各波潛伏期及波間潛伏期均較對照延長,差異有統(tǒng)計學(xué)意義(P0.05);輕中度組與重度組OSAHS相比波Ⅰ、Ⅲ潛伏期及Ⅰ-Ⅴ波間期的延長,差異有統(tǒng)計學(xué)意義(P0.05)。OSAHS的病情程度與BMI、阻塞部位、鼾聲指數(shù)、最低血氧飽和度關(guān)系密切(P0.05),并且不同病情程度的OSAHS患者的DPOAE檢出率、ABR異常率相比較差異有統(tǒng)計學(xué)意義(P0.05)�！窘Y(jié)論】OSAHS對維吾爾族聽覺功能有損害,其中耳蝸主動聽覺功能降低,尤以高頻聽力下降明顯,可能合并聽覺傳導(dǎo)通路中的聽神經(jīng)中樞段及聽覺中樞的損害,需聯(lián)合DPOAE和ABR綜合評估篩查聽覺損害,盡早發(fā)現(xiàn),及時干預(yù)。
[Abstract]:[objective] to evaluate the effect of obstructive sleep apnea hypopnea syndrome (OSAHS) on auditory function of Uygur people in Xinjiang, [methods] 70 Uygur adults were divided into mild, moderate and recombinant OSAHS patients by polysomnography (PSG) and 35 healthy Uygur adults as control group. Distortion product otoacoustic emission (DPOAE) and auditory brainstem response (ABR) were detected and analyzed in all subjects. The response amplitude of DPOAE and the changes of latency and interphase of ABR were compared to evaluate the impairment of auditory function. [results] the response amplitude of DPOAE in OSAHS patients was significantly lower than that in the control group (P0.05). Compared with the control group, the latency of wave 鈪，

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