【摘要】：本文研究了電誘發(fā)復合動作電位(ECAP)的刺激脈寬與閾值之間的關系。首先通過對已有實驗結果的擬合得到了單根聽神經動作電位的刺激脈寬和閾值關系式中的基強度和時基;而后基于ECAP的機制提出了一個描述其刺激脈寬與閾值之間關系的數學表達式;進一步通過豚鼠實驗得到了表達式的參數并驗證了表達式的適用性。研究結果表明,ECAP與單根聽神經動作電位對比,二者的刺激脈寬與閾值之間存在相似的函數關系,但前者的基強度比后者小一個數量級,而時基比較接近。這些結果對于臨床的ECAP測量與深入研究人工耳蝸的語音處理策略具有一定的指導意義。
[Abstract]:The relationship between the stimulus pulse width and the threshold of electroevoked compound action potential (ECAP) has been studied in this paper. Firstly, by fitting the experimental results, the basic intensity and time base of the stimulus pulse width and threshold of the action potential of the single auditory nerve are obtained. Based on the mechanism of ECAP, a mathematical expression describing the relationship between the stimulus pulse width and the threshold is proposed, and the parameters of the expression are obtained by guinea pig experiments and the applicability of the expression is verified. The results show that there is a similar functional relationship between the stimulation pulse width and the threshold of ECAP and the action potential of a single auditory nerve, but the base strength of the former is one order of magnitude less than that of the latter, but the time base is close. These results have certain guiding significance for clinical ECAP measurement and in-depth study of speech processing strategies of cochlear implants.
【作者單位】： 中國科學院聲學研究所;北京銳致聰科技有限公司;
【分類號】：O441.1;R764.3
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本文編號：2344603