本文關(guān)鍵詞： 鼻咽癌 放療 醫(yī)院感染 危險因素　出處：《中華醫(yī)院感染學(xué)雜志》2014年13期 　論文類型：期刊論文

【摘要】：目的分析鼻咽癌患者放療中發(fā)生醫(yī)院感染的危險因素,為臨床治療策略的制定提供參考。方法回顧性分析2011年3月-2013年3月行放療的72例鼻咽癌患者臨床資料,統(tǒng)計其醫(yī)院感染的發(fā)生率、感染部位、病原菌的分布及其危險因素;所有數(shù)據(jù)采用SPSS 17.0軟件進(jìn)行統(tǒng)計分析。結(jié)果 72例鼻咽癌患者中有57例發(fā)生醫(yī)院感染,感染率為79.17%;感染部位以口腔黏膜感染最多36例占63.16%,其次是皮膚感染13例占22.81%;檢出病原菌57株,以真菌為主38株占66.67%,其次革蘭陰性菌13株占22.80%、革蘭陽性菌6株占10.53%,檢出病原菌前3位依次為白色假絲酵母菌、鮑氏不動桿菌、熱帶假絲酵母菌,分別占50.88%、10.53%、8.77%;高齡、接受手術(shù)治療、住院30d、應(yīng)用抗菌藥物≥2種以及Ⅲ~Ⅳ期鼻咽癌是鼻咽癌患者放療中發(fā)生醫(yī)院感染的危險因素。結(jié)論鼻咽癌患者容易發(fā)生口腔黏膜部的感染,以真菌感染為主,臨床上應(yīng)縮短患者的住院天數(shù),規(guī)范進(jìn)行抗感染治療,及早發(fā)現(xiàn)和控制感染,以減少醫(yī)院感染的發(fā)生,提高患者的臨床療效。
[Abstract]:Objective to analyze the risk factors of nosocomial infection in patients with nasopharyngeal carcinoma (NPC) after radiotherapy, and to provide reference for the formulation of clinical treatment strategies. Methods the clinical data of 72 patients with nasopharyngeal carcinoma treated with radiotherapy from March 2011 to March 2013 were analyzed retrospectively. The incidence of nosocomial infection, the location of nosocomial infection, the distribution of pathogenic bacteria and the risk factors of nosocomial infection were analyzed by SPSS 17.0 software. Results 57 out of 72 patients with nasopharyngeal carcinoma had nosocomial infection. The infection rate was 79.17. The most common infection site was oral mucosal infection in 36 cases (63.16), followed by skin infection in 13 cases (22.81%), and 57 strains of pathogenic bacteria were detected. 38 strains of fungi accounted for 66.67%, 13 strains of Gram-negative bacteria accounted for 22.80, 6 strains of Gram-positive bacteria accounted for 10.53. The first three pathogenic bacteria were Candida albicans, Acinetobacter baumannii and Candida tropicalis, accounting for 50.888.538.775.At old age, they were treated surgically. For 30 days, the risk factors of nosocomial infection in patients with nasopharyngeal carcinoma (NPC) were higher than 2 antibiotics and stage 鈪，

本文編號：1544505