【摘要】：目的：在大多數(shù)惡性腫瘤當(dāng)中，升高的中性粒細(xì)胞/淋巴細(xì)胞比值（Neutrophil-to-LymphocyteRatio，NLR）提示腫瘤的不良預(yù)后，研究顯示，高中性粒細(xì)胞/淋巴細(xì)胞比值與胃癌、肝癌、肺癌、結(jié)腸癌、胰腺癌等腫瘤患者的死亡率密切相關(guān)。然而，中性粒細(xì)胞/淋巴細(xì)胞比值與鼻咽癌預(yù)后的關(guān)系仍然不是十分清楚，就此本文對(duì)中性粒細(xì)胞/淋巴細(xì)胞比值在鼻咽癌預(yù)后的臨床意義進(jìn)行探討。 方法：回顧性分析2001年1月至2010年1月我院116例鼻咽癌患者（男76例，女40例）,記錄年齡、性別、白細(xì)胞計(jì)數(shù)（WBC）、中性粒細(xì)胞計(jì)數(shù)（N）、淋巴細(xì)胞計(jì)數(shù)（L），并計(jì)算出中性粒細(xì)胞/淋巴細(xì)胞比值（NLR），比較116例患者中復(fù)發(fā)與未復(fù)發(fā)者年齡、性別、中性粒細(xì)胞計(jì)數(shù)（N）、淋巴細(xì)胞計(jì)數(shù)（L），NLR,分析比較年齡、性別、N、L、NRL對(duì)鼻咽癌患者預(yù)后的影響。 結(jié)果：復(fù)發(fā)組NLR明顯高于未復(fù)發(fā)組(P0.001)，復(fù)發(fā)組L低于未復(fù)發(fā)組（P0.05）。通過(guò)ROC曲線，NLR3.69時(shí)，其中未復(fù)發(fā)與復(fù)發(fā)比例：79.41%，，20.59%，NLR≥3.69時(shí)，未復(fù)發(fā)與復(fù)發(fā)比例：20.83%，79.17%。差異具有統(tǒng)計(jì)學(xué)意義（P0.001）。復(fù)發(fā)組性別與未復(fù)發(fā)組無(wú)明顯統(tǒng)計(jì)學(xué)差異（P0.05） 結(jié)論：NLR是一種新的炎癥指標(biāo)，NLR對(duì)鼻咽癌的預(yù)后復(fù)發(fā)有一定的預(yù)測(cè)價(jià)值，有望作為預(yù)測(cè)鼻咽癌預(yù)后的一種簡(jiǎn)單方便的生物指標(biāo)運(yùn)用于臨床工作中，值得臨床工作者的重視。
[Abstract]:Objective: in most malignant tumors, the increased Neutrophil-to-LymphocyteRatiolymphocyte ratio (NLR) indicates the poor prognosis of the tumor. Studies have shown that high neutrophil / lymphocyte ratio is associated with gastric cancer, liver cancer, lung cancer and colon cancer. The mortality of pancreatic cancer and other cancer patients is closely related. However, the relationship between the neutrophil / lymphocyte ratio and the prognosis of nasopharyngeal carcinoma is not very clear. In this paper, the clinical significance of neutrophil / lymphocyte ratio in the prognosis of nasopharyngeal carcinoma is discussed. Methods: from January 2001 to January 2010, 116 patients with nasopharyngeal carcinoma (76 males and 40 females) in our hospital were analyzed retrospectively. Leukocyte count (WBC), neutrophil count (N), lymphocyte count (L), and neutrophil / lymphocyte ratio (NLR), were calculated to compare the age and sex of recurrent and non-recurrent patients. Neutrophil count (N), lymphocyte count (L) / NLR) was used to analyze the influence of age and sex on the prognosis of nasopharyngeal carcinoma (NPC) patients. Results: the NLR of recurrent group was significantly higher than that of non-recurrent group (P0. 001), and the L of recurrent group was lower than that of non-recurrent group (P0.05). Through the ROC curve NLR 3.69, the ratio of no recurrence to recurrence was: 79.41% and 20.59NLR 鈮

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