發(fā)布時間：2018-06-26 01:40

  本文選題：眶尖綜合征 + 病因��； 參考：《中國神經(jīng)精神疾病雜志》2017年09期

【摘要】：目的探討眶尖綜合征的臨床特征、病因和預后。方法回顧性總結(jié)18例眶尖綜合征患者的臨床資料,并結(jié)合文獻進行分析。結(jié)果所有患者均出現(xiàn)視力減退、眼瞼下垂、復視、前額頭痛或眼痛等表現(xiàn),但其首發(fā)癥狀可不同,視力下降或喪失8例,頭痛、眼痛者7例,牙痛1例,鼻塞、流涕1例和眼球突出的1例。病因包括外傷6例(33%),占位5例(28%),非特異性炎癥4例(22%)、感染3例(17%)。住院期間6例外傷性患者中視力、眼球活動障礙等癥狀有好轉(zhuǎn)的5例,其中3例病情較輕者恢復更好,1例受傷較重的無好轉(zhuǎn);5例占位患者中1例蝶竇粘液囊腫患者手術(shù)后視力、眼球活動障礙等癥狀均有好轉(zhuǎn),其余4例診斷為眼眶腺樣囊性癌或放療后骨肉瘤患者無好轉(zhuǎn);4例非特異性炎癥疾病患者治療后2例視力、眼球活動障礙等癥狀較輕、病程較短的有好轉(zhuǎn),而另2例癥狀較重、病程較長的癥狀則無明顯好轉(zhuǎn);3例感染性疾病者1例病程較短的癥狀有好轉(zhuǎn),而另2例病程較長或合并顱內(nèi)感染患者無好轉(zhuǎn)。結(jié)論眶尖綜合征由多種病因引起,首發(fā)癥狀具有多樣性,其預后與病因、是否及時就診、早期診斷和早期治療相關(guān)。
[Abstract]:Objective to investigate the clinical features, etiology and prognosis of orbital apex syndrome. Methods the clinical data of 18 patients with orbital apex syndrome were retrospectively analyzed. Results all the patients had visual acuity, blepharoptosis, diplopia, prefrontal headache or eye pain, but their initial symptoms were different: vision loss or loss in 8 cases, headache, eye pain in 7 cases, toothache in 1 case, nasal obstruction in 1 case. Snot in 1 case and exophthalmos in 1 case. The etiology included trauma in 6 cases (33%), space occupying in 5 cases (28%), nonspecific inflammation in 4 cases (22%) and infection in 3 cases (17%). The visual acuity and eyeball movement disorder were improved in 5 cases in 6 traumatic patients during hospitalization. Among them, 3 cases recovered better than those with mild condition, 1 case had no improvement and 1 case had postoperative vision in 1 case of sphenoid sinus mucocele, which was more serious than that of the mild case, and the visual acuity of 1 case of sphenoid sinus mucocele was better than that of the mild case. The other 4 cases were diagnosed as orbital adenoid cystic carcinoma or osteosarcoma after radiotherapy. The shorter course of disease was better, while the other 2 cases had more severe symptoms, while the longer course of disease had no obvious improvement. One case of the shorter course of disease had improved, while the other 2 cases had no improvement in the longer course of disease or the patients with intracranial infection. Conclusion Orbital apex syndrome is caused by many causes, the initial symptoms are diverse, its prognosis and etiology, timely visit, early diagnosis and early treatment are related.
【作者單位】： 深圳市龍崗區(qū)第二人民醫(yī)院內(nèi)一科;中山大學附屬第一醫(yī)院神經(jīng)科;
【基金】：廣東省科技計劃項目(編號:2014A020212487)
【分類號】：R777.5

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本文編號：2068487