本文選題：阻塞性睡眠呼吸暫停低通氣綜合征 + 三維有限元法�。� 參考：《寧夏醫(yī)科大學(xué)》2012年碩士論文

【摘要】：目的建立阻塞性睡眠呼吸暫停低通氣綜合征（OSAHS）患者的上氣道及毗鄰結(jié)構(gòu)的三維有限元模型，通過(guò)下頜逐步前伸，觀察OSAHS患者舌體及舌后氣道的形態(tài)學(xué)改變，為OSAHS的口腔矯治器治療提供依據(jù)。 方法對(duì)OSAHS患者上氣道行薄層CT掃描，獲得OSAHS患者上氣道DICOM格式的圖像信息，采用Mimics三維建模軟件、Imageware逆向工程學(xué)軟件、Ansys有限元分析軟件建立上氣道及毗鄰結(jié)構(gòu)的三維有限元模型，然后通過(guò)加載下頜骨逐步前伸，觀察OSAHS患者舌體及舌后氣道的形態(tài)變化及規(guī)律。 結(jié)果建立了OSAHS患者上氣道及毗鄰結(jié)構(gòu)的三維有限元模型，單元類型采用10節(jié)點(diǎn)的Solid92四面體單元。劃分網(wǎng)格后，骨密質(zhì)、骨松質(zhì)、肌肉和氣道各得到的單元數(shù)和節(jié)點(diǎn)數(shù)分別為：562920、50141、336789個(gè)單元，544929、84869、303134個(gè)節(jié)點(diǎn)。通過(guò)下頜骨前伸，舌體及舌后氣道相應(yīng)發(fā)生形態(tài)變化，其主要表現(xiàn)為：舌體前移，舌后氣道平面其矢狀徑增大，橫徑相對(duì)減小，增加量大于減小量。 結(jié)論應(yīng)用螺旋CT技術(shù)和聯(lián)合使用Mimics三維建模軟件，Imageware軟件，Ansys有限元分析軟件建立OSAHS患者上氣道及毗鄰結(jié)構(gòu)的三維有限元模型，證實(shí)通過(guò)CT可建立準(zhǔn)確、可作靈活模擬操作的OSAHS患者上氣道及其周圍結(jié)構(gòu)三維有限元模型，其建模效率高、速度快，模型的幾何相似性較好，使用靈活；通過(guò)對(duì)有限元模型的下頜進(jìn)行不同前伸位置的加載，有效打開(kāi)舌后氣道。證實(shí)了有限元分析方法的有效性，，為下頜前伸矯治器治療OSAHS提供理論依據(jù)，同時(shí)為后續(xù)研究OSAHS患者上氣道生物力學(xué)分析打下良好的基礎(chǔ)。
[Abstract]:Objective to establish a three-dimensional finite element model of upper airway and adjacent structure in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). To provide the basis for oral appliance therapy of OSAHS. Methods the upper airway of OSAHS patients was scanned by thin slice CT, and the DICOM image of the upper airway of OSAHS patients was obtained. The 3D finite element model of upper airway and adjacent structure was established by using Mimics 3D modeling software / imageware reverse engineering software / Ansys finite element analysis software. Then, the morphology and regularity of tongue body and retrolingual airway of OSAHS patients were observed by mandibular extension. Results the 3D finite element model of upper airway and adjacent structure of OSAHS patients was established. The element type was 10 node Solid92 tetrahedron element. After meshing, the number of units and nodes in dense bone, cancellous bone, muscle and airway were 5449292984869 and 303134 nodes, respectively. According to the morphological changes of mandibular anterior extension, tongue body and retrolingual airway, the main features were as follows: the lingual body moved forward, the sagittal diameter of the retrolingual airway increased, the transverse diameter decreased, and the increment was greater than the decrease. Conclusion the 3D finite element model of upper airway and adjacent structure of patients with OSAHS can be established by using spiral CT and Mimics software imageware. It is proved that CT can be used to establish accurate 3D finite element model of upper airway and adjacent structure of patients with OSAHS. The 3D finite element model of upper airway and its surrounding structure of OSAHS patients, which can be simulated flexibly, has the advantages of high efficiency, high speed, good geometric similarity and flexible use. The postlingual airway was effectively opened by loading the mandible of finite element model at different protruding positions. It is proved that the finite element analysis method is effective, which provides a theoretical basis for the treatment of OSAHS with mandibular protruding appliance, and provides a good basis for further study on biomechanical analysis of upper airway in patients with OSAHS.
【學(xué)位授予單位】：寧夏醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R766

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 趙雪巖;黃任含;樓航迪;榮起國(guó);;阻塞性睡眠呼吸暫停綜合征的生物力學(xué)研究[J];北京大學(xué)學(xué)報(bào)(自然科學(xué)版);2009年05期

2 高雪梅,曾祥龍,傅民魁,黃席珍,陳雷;阻塞性睡眠呼吸暫停綜合征患者上氣道大小的磁共振研究[J];北京醫(yī)科大學(xué)學(xué)報(bào);1999年05期

3 曾祥龍;高雪梅;;阻塞性睡眠呼吸暫停低通氣綜合征的口腔醫(yī)學(xué)研究現(xiàn)狀[J];北京大學(xué)學(xué)報(bào)(醫(yī)學(xué)版);2009年01期

4 劉月華,曾祥龍,傅民魁,黃席珍;阻塞性睡眠呼吸暫停綜合征患者顱頜面形態(tài)的X線頭影測(cè)量研究[J];北京醫(yī)科大學(xué)學(xué)報(bào);1998年03期

5 郭學(xué)軍;王成林;劉鵬程;;病理性鼾癥的影像學(xué)診斷及其進(jìn)展[J];中國(guó)CT和MRI雜志;2007年01期

6 王瑩;孫秀珍;劉迎曦;于馳;張軍;于申;;OSAHS患者與正常人上呼吸道流場(chǎng)特性比較[J];大連理工大學(xué)學(xué)報(bào);2009年04期

7 胡娟;唐光健;;阻塞性睡眠呼吸暫停低通氣綜合征及其影像學(xué)研究[J];國(guó)際醫(yī)學(xué)放射學(xué)雜志;2009年05期

8 孫秀珍;于馳;劉迎曦;于申;張軍;蘇英鋒;;人體上呼吸道三維有限元重建與流場(chǎng)數(shù)值模擬[J];航天醫(yī)學(xué)與醫(yī)學(xué)工程;2006年02期

9 季俊峰;周玫;江滿杰;薛飛;王秋萍;;阻塞性睡眠呼吸暫停低通氣綜合征患者上氣道擴(kuò)張肌肌電活性的研究[J];醫(yī)學(xué)研究生學(xué)報(bào);2006年09期

10 溫偉生,胡敏,柳春明,王照五,石校偉;不同體位下舌骨位置與下咽氣道大小的相關(guān)性研究[J];口腔頜面修復(fù)學(xué)雜志;2001年03期

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