本文選題：聽性腦干電反應(yīng) + 非鎮(zhèn)靜　； 參考：《昆明醫(yī)科大學(xué)》2017年碩士論文

【摘要】：[目的]比較0～6歲兒童非鎮(zhèn)靜聽性腦干電反應(yīng)(Un-sedated auditory brainstem response,ABR)與傳統(tǒng)鎮(zhèn)靜聽性腦干電反應(yīng)的反應(yīng)閾及波V潛伏期,評(píng)價(jià)非鎮(zhèn)靜ABR在0～6歲兒童聽力評(píng)估中的意義,以及比較0～6歲不同年齡段聽力正常兒童非鎮(zhèn)靜ABR的V波潛伏期,進(jìn)一步探討非鎮(zhèn)靜ABR波V潛伏期的變化規(guī)律。[方法]將110例(220耳)0～6歲兒童根據(jù)年齡分為A(0～1歲)、B(1～3歲)、C(3～6歲)三組,其中A組38例(76耳),B組36例(72耳),C組36例(72耳),分別進(jìn)行非鎮(zhèn)靜ABR及鎮(zhèn)靜ABR測試。比較所有測試者非鎮(zhèn)靜ABR與鎮(zhèn)靜ABR反應(yīng)閾及波V潛伏期的相關(guān)性。同時(shí),比較不同年齡段聽力正常兒童,每組各20例(40耳),非鎮(zhèn)靜ABR波V潛伏期的差異。[結(jié)果]斯皮爾曼秩相關(guān)系數(shù)(Spearman's rho法)分析顯示非鎮(zhèn)靜ABR與鎮(zhèn)靜ABR反應(yīng)閾值顯著相關(guān)(r=0.917,P0.01),非鎮(zhèn)靜ABR與鎮(zhèn)靜ABR波V潛伏期顯著相關(guān)(r=0.888,P＜0.01);秩和檢驗(yàn)(Wilcoxon訊號(hào)等級(jí))分析顯示非鎮(zhèn)靜ABR與鎮(zhèn)靜ABR反應(yīng)閾值差異無統(tǒng)計(jì)學(xué)意義(Z=-0.674,P=0.500),非鎮(zhèn)靜ABR與鎮(zhèn)靜ABR波V潛伏期差異無統(tǒng)計(jì)學(xué)意義(Z=-2.438,P=0.15);Wilcoxon訊號(hào)等級(jí)分析顯示不同年齡組聽力正常兒童非鎮(zhèn)靜ABR波V潛伏期A(0～1歲)與B(1～3歲)差異有統(tǒng)計(jì)學(xué)意義(Z=-3.496,P0.05);A(0～1歲)與C(3～6歲)差異有統(tǒng)計(jì)學(xué)意義(Z=-3.982,P0.05),B(1～3歲)與C(3～6歲)差異無統(tǒng)計(jì)學(xué)意義(Z=-1.027,P=0.304)。[結(jié)論]兒童非鎮(zhèn)靜ABR與鎮(zhèn)靜ABR反應(yīng)閾及V波潛伏期有良好的相關(guān)性,非鎮(zhèn)靜ABR技術(shù)可以有效的應(yīng)用于兒童聽性腦干電反應(yīng)檢測,該技術(shù)適用于不適合使用鎮(zhèn)靜類藥物或不愿接受鎮(zhèn)靜的兒童受試者。
[Abstract]:[objective] to compare the threshold and V latency of unsedated auditory brainstem response and conventional sedation auditory brainstem response in children aged 0 to 6 years old, and to evaluate the significance of non-sedative ABR in hearing assessment of children aged 0 to 6 years old. The V wave latencies of non sedative ABR were compared between 0 and 6 years old children with normal hearing, and the changes of V latency of non sedation ABR waves were further discussed. [methods] 110 children aged 6 years old were divided into three groups: group A (38 cases, 76 ears), group B (36 cases, 72 ears), group C (36 cases, n = 72) were divided into three groups. The nonsedative ABR and sedative ABR test were performed respectively. The correlation between non-sedative ABR and sedation ABR reaction threshold and wave V latency was compared in all subjects. At the same time, the differences of V latency of non sedation ABR wave in 20 cases with 40 ears of normal hearing in each group were compared. [results] the Spelman rank correlation coefficient and Spearman's rho analysis showed that there was a significant correlation between non-sedative ABR and sedation ABR reaction threshold, and a significant correlation between non-sedative ABR and sedative ABR wave V latency (P < 0.01; rank sum test and Wilcoxon signal grade). There was no significant difference in the response threshold between non-sedative ABR and sedative ABR. There was no significant difference in V latency between non-sedative ABR and sedation ABR. There was significant difference between the age of 1 year (1 year) and the age of 1 year (3 years old). There was no significant difference between the two groups (ZHU -3.496P0.05P0.05P0.05P0.05- 1) and C3- (3-year-old) and C36-year-old) there was no significant difference between the two groups (P = 0.3040.304g / d, P = 0.304a, P = 0.304a, P = 0.304a, P = 0.304a, P = 0.304a, P = 0.304a, P = 0.304a, P = 0.304n = 0.304N). [conclusion] there is a good correlation between nonsedative ABR and ABR response threshold and V wave latency in children. Non-sedative ABR technique can be used to detect auditory brainstem response in children. This technique is suitable for children who are unsuitable for sedation or unwilling to accept sedation.
【學(xué)位授予單位】：昆明醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R764

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