本文選題：鼻咽癌　切入點：腫瘤體積　出處：《西安交通大學學報(醫(yī)學版)》2017年01期 　論文類型：期刊論文

【摘要】：目的探索鼻咽部腫瘤體積在中國西北非高發(fā)區(qū)鼻咽癌患者中的預后價值。方法將2004-2011年接受根治性放療的393例鼻咽癌患者納入本研究,所有患者均通過鼻咽部組織活檢明確為鼻咽癌,觀察總生存率和無遠處轉移生存率,采用ROC曲線確定腫瘤體積最佳界值,Kaplan-Meier比較患者生存差異,COX比例風險回歸模型探索獨立預后因素。結果患者5年總生存率和無遠處轉移生存率分別為74.3%和73.5%。根據(jù)腫瘤體積最佳界值將患者分為≤23mL組和23mL組,≤23mL組患者5年總生存率和無遠處轉移生存率明顯高于23mL組,差異有統(tǒng)計學意義(P0.05)。多因素分析顯示病理類型為分化亞型、腫瘤體積23mL、N2~3為影響患者總生存率和無遠處轉移生存率的獨立預后因素。結論鼻咽部腫瘤體積是影響中國西北非高發(fā)區(qū)鼻咽癌患者生存的獨立預后因素。
[Abstract]:Objective to explore the prognostic value of nasopharyngeal tumor volume in nasopharyngeal carcinoma (NPC) patients in non-high incidence areas of northwest China. Methods 393 patients with nasopharyngeal carcinoma received radical radiotherapy from 2004 to 2011 were included in this study. All the patients were identified as nasopharyngeal carcinoma by nasopharyngeal biopsy, and the overall survival rate and distant metastasis-free survival rate were observed. ROC curve was used to determine the best cutoff value of tumor volume. Kaplan-Meier compared survival difference of patients with Cox proportional risk regression model to explore independent prognostic factors. Results the 5-year overall survival rate and distant metastasis-free survival rate were 74.3% and 73.5 respectively. The best cutoff of tumor volume was divided into 鈮，

本文編號：1580207