本文關(guān)鍵詞： 睡眠呼吸暫停低通氣綜合征 高刺激率 聽性腦干反應(yīng)　出處：《聽力學(xué)及言語疾病雜志》2016年04期 　論文類型：期刊論文

【摘要】：目的探討高刺激率ABR對阻塞性睡眠呼吸暫停低通氣綜合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)患者聽力評估的價值及其與低氧血癥的相關(guān)性。方法對39例(78耳)OSAHS患者(中度5例、重度34例)和34例(68耳)正常成年人分別進(jìn)行11.1、31.1、51.1次"秒刺激率的聽性腦干反應(yīng)(ABR)測試,比較組間結(jié)果,并與多導(dǎo)睡眠監(jiān)測呼吸暫停低通氣指數(shù)(AHI)、最低血氧飽和度(LSaO2)、平均血氧飽和度(MSaO2)、氧飽和度≤90%的時間占總監(jiān)測時間的百分比(SIT90)、氧飽和度≤80%的時間占總監(jiān)測時間的百分比(SIT80)進(jìn)行相關(guān)性分析。結(jié)果在11.1次"秒刺激率時OSAHS組ABR波Ⅴ潛伏期(5.79±0.22ms)較對照組(5.67±0.24ms)延長;31.1次"秒刺激率時OSAHS組ABR波Ⅰ潛伏期(1.85±0.18ms)、波Ⅴ潛伏期(5.98±0.19ms)均較對照組(分別為1.76±0.16ms、5.82±0.24ms)延長;在51.1次"秒刺激率時OSAHS組ABR波Ⅰ潛伏期(1.94±0.26ms)、波Ⅴ潛伏期(6.09±0.25ms)較對照組(分別為1.83±0.15ms、5.99±0.24ms)延長。刺激率由11.1次"秒升高至31.1次"秒時,OSAHS組波Ⅰ潛伏期延長,ΔⅠ_(31.1-11.1)(0.12±0.17ms)較對照組(0.07±0.11ms)長,刺激率由11.1次"秒升高至51.1次"秒時,OSAHS組波Ⅰ潛伏期延長,ΔⅠ51.1-11.1(0.21±0.25ms)較對照組(0.15±0.10ms)長。ΔⅠ_(31.1-11.1)與LSaO2負(fù)相關(guān)(r=-0.24),與SIT90(r=0.23)、SIT80(r=0.27)正相關(guān);ΔⅠ51.1-11.1與LSaO2(r=-0.33)、MSaO2(r=-0.35)負(fù)相關(guān),與SIT90(r=0.37)、SIT80(r=0.29)正相關(guān);以上差異及相關(guān)性均有統(tǒng)計學(xué)意義(p0.05)。結(jié)論高刺激率ABR可發(fā)現(xiàn)中度及重度OSAHS患者耳蝸及聽神經(jīng)近耳蝸段的損傷。
[Abstract]:Objective to investigate the value of high stimulation rate ABR in hearing evaluation of patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) and its correlation with hypoxemia. Methods 39 cases (5 moderate cases) of OSAHS with 78 ears of obstructive sleep apnea hypopnea syndrome (OSAHS) were studied. The auditory brainstem response (ABR) test was performed in 34 severe cases (n = 34) and 34 normal adults (n = 34). The results of ABR were compared between the two groups, and the auditory brainstem response (ABR) was measured at the rate of 51.1 "second stimuli". With polysomnography, apnea hypopnea index (apnea hypopnea index), minimum oxygen saturation (LSAO _ 2), mean oxygen saturation (MSaO _ 2), oxygen saturation 鈮，

本文編號：1521039