本文關(guān)鍵詞：MGD對年齡相關(guān)性白內(nèi)障超聲乳化術(shù)后視覺質(zhì)量影響的研究　出處：《廣西醫(yī)科大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 瞼板腺功能障礙 白內(nèi)障超聲乳化術(shù) 視覺質(zhì)量 淚膜破裂時間 相關(guān)性分析 回歸分析

【摘要】：目的評估術(shù)前是否合并有瞼板腺功能障礙(Meibomian gland dysfunction, MGD)以及MGD嚴(yán)重程度對年齡相關(guān)性白內(nèi)障超聲乳化術(shù)后視覺質(zhì)量的影響。方法前瞻性臨床研究。術(shù)前根據(jù)患者是否合并有MGD以及MGD的嚴(yán)重程度分為A、B、C三組：A組28例(35眼)術(shù)前無MGD,B組26例(35眼)術(shù)前合并有輕度MGD,C組28例(35眼)術(shù)前合并有中度MGD。術(shù)后隨訪1天、1周、1月、≥3月(3.44±0.44月),檢查并記錄裸眼遠視力(uncorreted distance visual acuity, UDVA)、3mm瞳孔直徑下的總高階像差(HO Total)、慧差(Coma)、球差(Spherical)、三葉草(Trefoil)、視覺質(zhì)量滿意度問卷調(diào)查以及淚膜破裂時間(tear break up time,BUT)。結(jié)果1)術(shù)后1天,A組和B組、A組和C組、B組和C組UDVA、HO Total、 Coma、Spherical、TrefoIL、視覺質(zhì)量滿意度比較差異無統(tǒng)計學(xué)意義。2)術(shù)后1周,A組和B組、A組和C組HO T otal、Coma、Trefoil匕較差異有統(tǒng)計學(xué)差異(P0.05), UDVA、Spherical、視覺質(zhì)量滿意度比較差異無統(tǒng)計學(xué)意義；B組和C組UDVA、HO Total、Coma、Spherical、Trefoil、視覺質(zhì)量滿意度比較差異無統(tǒng)計學(xué)意義。3)術(shù)后1月,A組和B組、A組和C組Coma比較差異有統(tǒng)計學(xué)差異(P0.05,UDVA、HO Total、Spherical、Trefoil、視覺質(zhì)量滿意度比較差異無統(tǒng)計學(xué)意義；B組和C組UDVA、HO Total、Coma、Spherical、Trefoilv視覺質(zhì)量滿意度比較差異無統(tǒng)計學(xué)意義。4)術(shù)后≥3月,A組和B組、A組和C組、B組和C組HO Total、Trefoil比較差異有統(tǒng)計學(xué)差異(P0.05); UDVA、Coma、Spherical比較差異無統(tǒng)計學(xué)意義。5)MGD患者(B組和C組)術(shù)后視覺質(zhì)量與BUT的相關(guān)性分析得出,術(shù)后≥3月HO Total、Trefoil與BUT的相關(guān)性有統(tǒng)計學(xué)意義(P0.05),且呈負相關(guān)；Coma、Spherical與BUT的相關(guān)性無統(tǒng)計學(xué)意義。術(shù)后1天、1周、1月H0 Total、Coma、Spherical、Trefoil與BUT的相關(guān)性無統(tǒng)計學(xué)意義。6)術(shù)后視覺質(zhì)量與MGD等級的回歸分析得出,術(shù)后≥3月HO Total、Trefoil與MGD等級的回歸分析有統(tǒng)計學(xué)意義(P0.05),Coma、Spherical與MGD等級的回歸分析無統(tǒng)計學(xué)意義。術(shù)后1天、1周、1月H0 Total、Coma、Spherical、Trefoil與MGD等級的回歸分析無統(tǒng)計學(xué)意義。結(jié)論1)術(shù)前無MGD患者術(shù)后視覺質(zhì)量要優(yōu)于術(shù)前合并有MGD患者。2)術(shù)后≥3月,MGD患者的視覺質(zhì)量與淚膜穩(wěn)定性呈正相關(guān)。3)術(shù)后≥3月,患者的視覺質(zhì)量與MGD等級呈負相關(guān)。
[Abstract]:Objective to evaluate the effect of Meibomian gland dysfunction (MGD) and the severity of MGD on visual quality of age-related cataract after phacoemulsification. Methods a prospective clinical study. According to whether the patients were combined with MGD and the severity of MGD, they were divided into three groups: A, B and C. There were 28 cases (35 eyes) in A group, 26 cases (35 eyes) in B group, 26 cases (35 eyes) in B group, 28 cases in preoperative group, 28 cases in C group (35 eyes). The postoperative follow-up was 1 days, 1 week, January, March (aged 3.44 + 0.44 months), check and record the uncorrected visual acuity (uncorreted distance visual acuity, UDVA), the total higher-order aberrations of the pupil diameter of 3mm (HO Total), coma (Coma), spherical aberration (Spherical) and Clover (Trefoil), visual quality satisfaction questionnaire and tear break-up time (tear break up time, BUT). Results 1) 1 days after operation, there was no significant difference in UDVA, HO Total, Coma, Spherical, and visual quality of A group and B group, A group and C group, B group and C group. 2) 1 weeks after operation, A group and B group, A group and C group, HO T otal, Coma, Trefoil, there was significant difference between the difference (P0.05), UDVA, Spherical, visual quality satisfaction, no significant difference was not statistically significant; B group and C group UDVA, HO Total, Coma, Spherical Trefoil and visual quality satisfaction difference. 3) after January, there is significant difference between the A group and B group, A group and C group Coma (P0.05, UDVA, HO between Total, Spherical, Trefoil, visual quality satisfaction was no statistically significant difference between B group and C group; UDVA, HO Total, Coma, Spherical, Trefoilv visual quality satisfaction comparison there was no statistically significant difference. 4) after more than March, there is significant difference between the A group and B group, A group and C group, B group and C group, HO Total Trefoil (P0.05); the difference was not statistically significant UDVA, Coma, Spherical difference. 5) MGD patients (B group and C group) and BUT analysis of the correlation of visual quality after that, after more than Total, Trefoil and HO between March BUT was statistically significant (P0.05), and was negatively correlated with Coma, Spherical and BUT; the correlation was not statistically significant. There was no statistically significant correlation between H0 Total, Coma, Spherical, Trefoil and BUT in 1 days, 1 weeks and January after the operation. 6) regression grade postoperative visual quality and MGD analysis, after the March HO Total Trefoil, or regression analysis with MGD grade was statistically significant (P0.05), Coma, Spherical and MGD level regression analysis was not statistically significant. There was no statistical significance in the regression analysis of H0 Total, Coma, Spherical, Trefoil and MGD levels in 1 days, 1 weeks and January after the operation. Conclusion 1. The visual quality of patients without MGD before operation is better than that of patients with MGD before operation. 2) after more than March, the visual quality of patients with MGD was positively related with the stability of tear film. 3) after more than March, the visual quality of patients was negatively correlated with MGD level.
【學(xué)位授予單位】：廣西醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R779.6

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