本文關(guān)鍵詞：立體定向海馬深部電極置入在顳葉癲癇外科中的應(yīng)用，由筆耕文化傳播整理發(fā)布。

立體定向海馬深部電極置入在顳葉癲癇外科中的應(yīng)用

Stereotactic hippocampal deep electrodes implanted in the application of temporal lobe epilepsy surgery

[1] [2] [3] [4] [5] [6] [7]

Shi Jian ,Wei Xiangpin ,Liu Xiang, et al.（ Department of Neurosurgery ,Affiliated Provincial Hospital of Anhui Medical University, Hefei , 230001, China）

安徽醫(yī)科大學(xué)附屬省立醫(yī)院神經(jīng)外科;腦功能與腦疾病安徽省重點(diǎn)實(shí)驗(yàn)室,合肥230001

文章摘要：目的探討應(yīng)用立體定向技術(shù)雙側(cè)海馬置入深部電極腦電監(jiān)測(cè)對(duì)顳葉癲癇的定側(cè)定位價(jià)值。方法對(duì)15例無創(chuàng)影像及腦電檢查難以定側(cè)定位的顳葉癲癇患者,在MR定位引導(dǎo)下行立體定向雙側(cè)海馬深部電極置入,視頻腦電監(jiān)測(cè)描記發(fā)作期及發(fā)作間期腦電圖,根據(jù)監(jiān)測(cè)結(jié)果對(duì)癲癇灶進(jìn)行定側(cè)定位,行個(gè)體化癲癇外科手術(shù)治療,術(shù)后正規(guī)口服抗癲癇藥物并隨訪。結(jié)果術(shù)后隨訪最長(zhǎng)44個(gè)月,最短8個(gè)月,平均21個(gè)月。療效滿意8例（54%）,顯著改善5例（33%）,良好2例（13%）。術(shù)后1例出現(xiàn)視野缺損,無其他嚴(yán)重并發(fā)癥。結(jié)論立體定向雙側(cè)海馬深部電極置入及腦電監(jiān)測(cè),微創(chuàng)、安全、準(zhǔn)確,是難治性顳葉癲癇定側(cè)定位的可靠的方法,對(duì)制定個(gè)體化手術(shù)方案具有決定性作用。

Abstr：Objective To discuss the value of stereotactie implanting hippocampal depth EEGs monitoring to localize the epileptogenic zone in temporal lobe epilepsy.Methods The depth electrodes were implanted in hippocampus in the guidance of MR and stereotactic in 15 patients with temporal lobe epilepsy,whose epileptogenic zone were difficulty to be localized or lateralized.Using video eeg monitoring to trace stage attacks and attacks between electroencephalogram.Epileptogenic zones were determined according to the monitoring results,and adopted individualized epilepsy surgery,regular oral antiepileptic drugs and follow-up after surgery.Results The longest postoperatie obseration period was 44 months,the shortest 8months,an average of21 months.The following-up outcomes showed that the satisfaction were 8cases（54%）,significant improvements were 5cases（33%）,good was two cases（13%）.There were no serious complications.Only one patient postoperative appeared with visual field defect.Conclusion To record hippocampal EEG in patients with intractable epilepsy by stereotactic implanting depth elcctrode into the hippocampus is a minimally invasive,safe and accurate method to localize lateralize epileptogenic zones in patients with temporal lobe epilepsy.It has a decisive role in formulate individualized operation scheme.

文章關(guān)鍵詞：

Keyword：:Temporal lobe epilepsy Stereotactjc technique Eleclroencephalography Depth eleetrode Hippocampus

課題項(xiàng)目：安徽省衛(wèi)生廳醫(yī)學(xué)科研課題項(xiàng)目（編號(hào)：13zc036）; 安徽省重點(diǎn)實(shí)驗(yàn)室績(jī)效考核補(bǔ)助項(xiàng)目（編號(hào)：1306c083028）

作者信息：會(huì)員可見

  本文關(guān)鍵詞：立體定向海馬深部電極置入在顳葉癲癇外科中的應(yīng)用，由筆耕文化傳播整理發(fā)布。