【摘要】：目的探討多形性膠質(zhì)母細(xì)胞瘤(GBM)標(biāo)準(zhǔn)STUPP方案后長周期替莫唑胺(TMZ)治療的療效。方法回顧性總結(jié)2009至2015年51例GBM患者,是否接受長周期TMZ進(jìn)行療效分析。結(jié)果入組患者中17例接受至少8周期TMZ化療,無進(jìn)展生存期為24.1個月(P=0.011),總生存期為29.3個月(P=0.004)。結(jié)論標(biāo)準(zhǔn)治療方案后長周期TMZ治療是安全、可行的,可一定程度改善PFS和OS,但是否臨床獲益仍需進(jìn)一步前瞻性隨機(jī)分組研究。
[Abstract]:Objective to investigate the efficacy of long cycle temozolamine (TMZ) in the treatment of pleomorphic glioblastomas after (GBM) standard STUPP regimen. Methods the efficacy of 51 patients with GBM from 2009 to 2015 was analyzed by long cycle TMZ. Results 17 patients received at least 8 cycles of TMZ chemotherapy. The progression-free survival time was 24.1 months (P 鈮，

本文編號：2473348