發(fā)布時間：2018-11-25 12:49

【摘要】：目的觀察偏頭痛患者右向左分流(right-to-left shunt,RLS)的發(fā)生率,分析偏頭痛與右向左分流的相關(guān)性。方法入選116例確診為偏頭痛的患者為病例組,75例健康志愿者為對照組,應(yīng)用對比增強(qiáng)經(jīng)顱多普勒超聲(contrast-enhanced transcranial Doppler,c-TCD)診斷RLS并對分流量進(jìn)行分級,分析兩組的陽性率,進(jìn)行統(tǒng)計(jì)分析。結(jié)果病例組中,RLS的陽性率為50.9%(59/116),其中,Ⅰ級分流35例(30.2%),Ⅱ級分流3例(2.6%),Ⅲ級分流7例(6.0%),Ⅳ級分流14例(12.1%)。對照組中,RLS的陽性率為30.6%(23/75),其中,Ⅰ級分流18例(24.0%),Ⅱ級分流1例(1.3%),Ⅲ級分流0例(0%),Ⅳ級分流4例(5.3%)。兩組RLS總陽性率的比較,病例組的RLS總陽性率高于對照組,統(tǒng)計(jì)學(xué)有顯著差異(P=0.006,χ~2=7.583);病例組的大量分流率顯著高于對照組(P=0.011,χ~2=6.530),但兩組的小量分流率比較無統(tǒng)計(jì)學(xué)差異(P=0.273,χ~2=1.199)。結(jié)論偏頭痛與右向左分流存在相關(guān),大量分流可能是偏頭痛的病因,應(yīng)引起臨床重點(diǎn)關(guān)注。
[Abstract]:Objective to observe the incidence of right to left shunt (right-to-left shunt,RLS) in patients with migraine and to analyze the correlation between migraine and right left shunt. Methods RLS was diagnosed by contrast enhanced transcranial Doppler (contrast-enhanced transcranial Doppler,c-TCD) in 116 patients with migraine and 75 healthy volunteers as control group. The positive rate of the two groups was analyzed and statistical analysis was carried out. Results the positive rate of RLS was 50.9% (59 / 116), including 35 cases of grade 鈪，

本文編號：2356163