~1HMRS在鑒別腦內(nèi)單發(fā)環(huán)形強(qiáng)化病變中的應(yīng)用
[Abstract]:Objective to analyze the application of 3.0T proton magnetic resonance spectroscopy (1HMRS) in differentiating single ring enhancement lesions in brain. Methods PHILIPS 3.0T magnetic resonance scanner was used to scan 1HMRS in 65 patients with single ring-enhanced lesions in the brain during MRI enhancement. 30 cases of high-grade gliomas were confirmed by pathology or clinical diagnosis. There were 23 cases of single brain metastasis and 12 cases of brain abscess. The subpeak area of NAA,Cho and Cr in the center of the lesion and the surrounding edema area were measured, the NAA/Cr,Cho/Cr,NAA/Cho ratio was calculated, and the Lac and Lip peaks in the center of the lesion were recorded. The diagnostic value of each parameter value in differentiating the three diseases was determined by statistical analysis. Results the Cho value of the center of the lesion was glioma. Metastatic tumor? Brain abscess; Cho/Cr value glioma? Brain abscess (P0. 05); NAA/Cho? Metastatic tumor? There was no significant difference in NAA and NAA/Cr between the three groups. NAA/Cr metastasis in peripheral edema? There was significant difference in Cho/Cr ratio between brain abscess group and glioma group (P0. 001). Brain abscess group? The sensitivity and specificity of high grade glioma were 73.3 and 94.4 when the Cho/Cr threshold value was 1.5650 and the high grade glioma group was significantly higher than that of single brain metastases group (P0. 000). The area under the ROC curve is 0.921. The difference of NAA/Cho in peripheral edema was statistically significant (P0. 001). The NAA/Cho of metastatic tumor group was higher than that of glioma group and brain abscess group. The occurrence rate of Lip peak in high grade glioma was lower than that in metastatic tumor and brain abscess, and there was no significant difference between metastatic tumor and brain abscess group. Conclusion 1HMRS can be used to differentiate the single ring-enhanced lesions in the brain. The ratio of NAA/Cho in the center of the lesion to Cho/Cr in the peripheral edema area is of great significance for the differential diagnosis of high-grade gliomas, single brain metastases and brain abscesses.
【作者單位】： 哈爾濱醫(yī)科大學(xué)附屬第四醫(yī)院醫(yī)學(xué)影像科;
【分類號】：R739.41;R445.2
【相似文獻(xiàn)】
相關(guān)期刊論文 前10條
1 李響;牛蕾;田小軍;蘇華偉;馬敏閣;隋慶蘭;;磁共振灌注成像對腦內(nèi)環(huán)形強(qiáng)化病變的鑒別診斷價值[J];青島大學(xué)醫(yī)學(xué)院學(xué)報;2013年02期
2 何雨潔;汪晶瑩;向旭;周曉鋒;肖志剛;何春香;;腦內(nèi)環(huán)形增強(qiáng)病變的CT診斷[J];影像診斷與介入放射學(xué);2006年06期
3 吳蔚;楊志英;楊清;;幕上腦內(nèi)環(huán)形強(qiáng)化病變的低場MRI診斷[J];西部醫(yī)學(xué);2012年09期
4 何明穎;楊毅;黃瑩;梁禮平;;彌散加權(quán)成像在腦內(nèi)常見單發(fā)環(huán)形強(qiáng)化病變中的診斷價值[J];醫(yī)學(xué)影像學(xué)雜志;2011年07期
5 鄺菲;王飛;陸建平;劉崎;王莉;;腦部環(huán)形強(qiáng)化病灶的磁共振波譜分析[J];第二軍醫(yī)大學(xué)學(xué)報;2006年09期
6 王廷昱;腦內(nèi)環(huán)形強(qiáng)化轉(zhuǎn)移瘤的MRI研究[J];放射學(xué)實(shí)踐;2003年06期
7 梁有祿;肖恩華;黃永杰;裴銳昌;宋國武;陳琪;;顱內(nèi)環(huán)形強(qiáng)化病變的MRI特征[J];醫(yī)學(xué)研究雜志;2007年03期
8 易志軍;馮朝燕;鄭海軍;彭國洪;劉堯斌;李武元;胡敏;黃勇;;顱內(nèi)環(huán)形強(qiáng)化病變的MRI診斷[J];實(shí)用臨床醫(yī)學(xué);2014年02期
9 陳成華;;顱內(nèi)環(huán)形強(qiáng)化病變CT診斷[J];吉林醫(yī)學(xué);2012年16期
10 周儀;顱腦環(huán)形強(qiáng)化病灶的CT診斷與鑒別診斷[J];實(shí)用放射學(xué)雜志;2001年04期
相關(guān)會議論文 前3條
1 梁有祿;;顱內(nèi)環(huán)形強(qiáng)化病變的MRI特征[A];中華醫(yī)學(xué)會第十三屆全國放射學(xué)大會論文匯編（下冊）[C];2006年
2 張宗軍;;MR擴(kuò)散加權(quán)在腦內(nèi)環(huán)形強(qiáng)化病灶鑒別診斷中的價值[A];中華醫(yī)學(xué)會第十三屆全國放射學(xué)大會論文匯編（下冊）[C];2006年
3 白俠;王雪梅;;~(11)C-CHO與~(18)F-FDG腦顯像在鑒別MRI腦環(huán)形強(qiáng)化病變良惡性中的應(yīng)用價值[A];中華醫(yī)學(xué)會第九次全國核醫(yī)學(xué)學(xué)術(shù)會議論文摘要匯編[C];2011年
相關(guān)碩士學(xué)位論文 前3條
1 馬媛媛;磁共振環(huán)形增強(qiáng)病變影像特點(diǎn)的回顧性研究[D];南方醫(yī)科大學(xué);2016年
2 賈守強(qiáng);最大似然法用于腦內(nèi)MRI環(huán)形強(qiáng)化病灶診斷及鑒別診斷的研究[D];山東大學(xué);2005年
3 王帥;肝臟多房環(huán)形強(qiáng)化病變的影像分析[D];蘇州大學(xué);2014年
，本文編號：2355309
本文鏈接：http://sikaile.net/yixuelunwen/shenjingyixue/2355309.html
