發(fā)布時(shí)間：2018-10-05 18:16

【摘要】：目的探討ABCD2評(píng)分與短暫性腦缺血發(fā)作(TIA)15 d內(nèi)預(yù)后的關(guān)系。方法選擇TIA患者224例。以住院15 d為觀察終點(diǎn),期間進(jìn)展為完全性腦梗死患者75例為進(jìn)展組,未進(jìn)展為完全性腦梗死患者149例為未進(jìn)展組。采用自行設(shè)計(jì)TIA調(diào)查表進(jìn)行調(diào)查,采用ABCD2評(píng)分系統(tǒng)對(duì)全部TIA患者進(jìn)行評(píng)估。結(jié)果 (1)ABCD2評(píng)分系統(tǒng)中,有糖尿病史的TIA患者進(jìn)展為腦梗死的危險(xiǎn)是無糖尿病者的2.585倍(OR=2.585,95%CI:1.457~4.588);隨著TIA持續(xù)時(shí)間增加,TIA患者進(jìn)展為腦梗死的比例增加(χ~2=52.847,P=0.000);隨著臨床特征加重,TIA患者進(jìn)展為腦梗死的比例增加(χ~2=42.535,P=0.000)。(2)隨著ABCD2評(píng)分的增加,TIA患者進(jìn)展為腦梗死的比例增加(χ~2=118.601,P=0.000);ABCD2評(píng)分危險(xiǎn)分層與TIA患者預(yù)后的關(guān)系中,低�；颊邲]有進(jìn)展為腦梗死,中危患者進(jìn)展為腦梗死的比例為22.5%,高�；颊哌M(jìn)展為腦梗死的比例為88.1%,差異有統(tǒng)計(jì)學(xué)意義(χ~2=107.600,P=0.000)。結(jié)論 ABCD2評(píng)分增加與TIA患者15 d內(nèi)進(jìn)展為腦梗死密切相關(guān),ABCD2評(píng)分危險(xiǎn)分層為中、高危TIA患者為臨床重點(diǎn)干預(yù)人群。
[Abstract]:Objective to investigate the relationship between ABCD2 score and prognosis of transient ischemic attack (TIA) within 15 days. Methods 224 patients with TIA were selected. After 15 days of hospitalization, 75 patients with complete cerebral infarction and 149 patients with incomplete cerebral infarction were observed as progression group. A self-designed TIA questionnaire was used to evaluate all TIA patients. Results (1) in the ABCD2 scoring system, The risk of progression to cerebral infarction in TIA patients with history of diabetes was 2.585 times higher than that in patients without diabetes mellitus (OR=2.585,95%CI:1.457~4.588), and the proportion of patients with TIA progression to cerebral infarction increased with the duration of TIA (蠂 ~ 2 / 2, 52.847, P ~ (0.000), and with the exacerbation of clinical features, the rate of progression to cerebral infarction was higher in patients with TIA than in patients without diabetes mellitus (P ~ (0.000). With the increase of ABCD2 score, the proportion of patients with progressive cerebral infarction (蠂 2 / 2) increased (蠂 2 / 118.601 / 0. 000) and the risk stratification of ABCD2 score was associated with the prognosis of TIA patients. The proportion of middle risk patients with cerebral infarction was 22.50.The proportion of high-risk patients with cerebral infarction was 88.1.The difference was statistically significant (蠂 2 107.600 P 0.000). Conclusion the increase of ABCD2 score is closely related to the progression of cerebral infarction in patients with TIA within 15 days. The risk stratification of ABCD2 score is middle, and the high risk TIA patients are the key intervention population.
【作者單位】： 襄陽(yáng)市谷城縣人民醫(yī)院神經(jīng)內(nèi)科;湖北文理學(xué)院醫(yī)學(xué)院;
【基金】：湖北文理學(xué)院與谷城縣人民醫(yī)院橫向合作課題(HY2013112)
【分類號(hào)】：R743.31

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