【摘要】：目的： 探討中樞神經系統(tǒng)表面含鐵血黃素沉積癥(superficial siderosis,SS)的影像表現(xiàn)。方法： 應用西門子3.0T磁共振成像系統(tǒng)(Verio,Siemens Medical Systems,Erlangen, Germany),對具有2年以上顱腦創(chuàng)傷或手術病史的患者行MRI檢查,參數(shù)如下：軸位T1WI(TI/TR/TE:823/1900/9),T2WI(TR/TE:6000/96),T2-FLAIR (TI/TR/TE:2140/6600/94),T2*WI(TR/TE:620/20),矢狀位T1WI,T2WI及MR腦池造影(TR/TE:1500/224)。 結果： 中樞神經系統(tǒng)表面含鐵血黃素沉積癥是一種少見的神經系統(tǒng)疾病,主要表現(xiàn)為雙側感音性耳聾、共濟失調及脊髓病變。常見致病原因是慢性蛛網膜下腔出血所致的含鐵血黃素沉積于腦和脊髓表面,需要依據(jù)磁共振T2WI圖像上所顯示的T2低信號來進行診斷,當MRI變化輕微時,可能會延緩該病的診斷,因此準確的臨床評價及正確的影像檢查技術可最大限度地使該病得以診斷。MRI圖像顯示含鐵血黃素沉積于腦及脊髓軟膜,T2WI序列顯示為特征性的線樣低信號。為避免中樞神經系統(tǒng)的不可逆損害,即便是該病相關的微小MR征象也不應被低估。SS的影像學表現(xiàn)與蛛網膜下腔出血相關。SS是慢性蛛網膜下腔出血沉積于腦和脊髓表面。經典三聯(lián)征包括雙側感音性耳聾、共濟失調及脊髓病變,而且T2MRI的特異性征象為腦干、小腦及脊髓表面的低信號。可導致慢性蛛網膜下腔出血的常見原因包括中樞神經系統(tǒng)腫瘤,頭頸部創(chuàng)傷,動靜脈畸形等,仍有近三分之一病例的病因不明。如該病被早期發(fā)現(xiàn),可以通過遏制出血來源進行治療,但該病的自然病程是一種漸進性的神經系統(tǒng)功能的低下。 結論： 中樞神經系統(tǒng)的SS為少見的綜合征,行MRI檢查,尤其T2WI序列具有重要診斷價值。
[Abstract]:Objective: to investigate the imaging features of hemosiderosis (superficial siderosis,SS) on the surface of the central nervous system (CNS). Methods: Siemens 3.0T magnetic resonance imaging system (Verio,Siemens Medical Systems,Erlangen, Germany),) was used to examine MRI in patients with more than 2 years history of craniocerebral trauma or surgery. The parameters were as follows: axial T1WI (TI/TR/TE:823/1900/9) T2WI (TR/TE:6000/96) T2-flair (TI/TR/TE:2140/6600/94) T2-flair T2WI (TR/TE:620/20), sagittal T1WII-T2WI and MR cisternography (TR/TE:1500/224). Results: hemosiderin deposition on the surface of central nervous system is a rare disease of nervous system with bilateral sensorineural deafness ataxia and myelopathy. The common cause is the deposition of hemosiderin on the surface of the brain and spinal cord due to chronic subarachnoid hemorrhage, which needs to be diagnosed on the basis of T 2 low signal intensity shown on T2WI images. When MRI changes slightly, May delay the diagnosis of the disease, Therefore, accurate clinical evaluation and correct imaging techniques can maximize the diagnosis of the disease. MRI images show that hemosiderin is deposited in the brain and spinal cord pial membrane on T2WI sequence showing characteristic linear hypotension. In order to avoid irreversible damage to the central nervous system, even small MR signs associated with the disease should not be underestimated. The imaging findings of SS are associated with subarachnoid hemorrhage. SS is a chronic subarachnoid hemorrhage deposited on the surface of the brain and spinal cord. Classic triple signs include bilateral sensorineural deafness, ataxia and spinal cord lesions, and the specific signs of T2MRI are low signal intensity on the surface of the brain stem, cerebellum and spinal cord. The common causes of chronic subarachnoid hemorrhage include central nervous system tumor, head and neck trauma, arteriovenous malformation and so on. If the disease is detected early, it can be treated by curbing the source of bleeding, but the natural course of the disease is a progressive decline in nervous system function. Conclusion: SS in central nervous system is a rare syndrome. MRI examination, especially T2WI sequence, has important diagnostic value.
【學位授予單位】：山東大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R445.2;R741

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本文編號：2213012