中樞神經(jīng)系統(tǒng)表面含鐵血黃素沉積癥的磁共振成像研究
發(fā)布時(shí)間：2018-08-30 12:00
【摘要】：目的： 探討中樞神經(jīng)系統(tǒng)表面含鐵血黃素沉積癥(superficial siderosis,SS)的影像表現(xiàn)。方法： 應(yīng)用西門子3.0T磁共振成像系統(tǒng)(Verio,Siemens Medical Systems,Erlangen, Germany),對(duì)具有2年以上顱腦創(chuàng)傷或手術(shù)病史的患者行MRI檢查,參數(shù)如下：軸位T1WI(TI/TR/TE:823/1900/9),T2WI(TR/TE:6000/96),T2-FLAIR (TI/TR/TE:2140/6600/94),T2*WI(TR/TE:620/20),矢狀位T1WI,T2WI及MR腦池造影(TR/TE:1500/224)。 結(jié)果： 中樞神經(jīng)系統(tǒng)表面含鐵血黃素沉積癥是一種少見(jiàn)的神經(jīng)系統(tǒng)疾病,主要表現(xiàn)為雙側(cè)感音性耳聾、共濟(jì)失調(diào)及脊髓病變。常見(jiàn)致病原因是慢性蛛網(wǎng)膜下腔出血所致的含鐵血黃素沉積于腦和脊髓表面,需要依據(jù)磁共振T2WI圖像上所顯示的T2低信號(hào)來(lái)進(jìn)行診斷,當(dāng)MRI變化輕微時(shí),可能會(huì)延緩該病的診斷,因此準(zhǔn)確的臨床評(píng)價(jià)及正確的影像檢查技術(shù)可最大限度地使該病得以診斷。MRI圖像顯示含鐵血黃素沉積于腦及脊髓軟膜,T2WI序列顯示為特征性的線樣低信號(hào)。為避免中樞神經(jīng)系統(tǒng)的不可逆損害,即便是該病相關(guān)的微小MR征象也不應(yīng)被低估。SS的影像學(xué)表現(xiàn)與蛛網(wǎng)膜下腔出血相關(guān)。SS是慢性蛛網(wǎng)膜下腔出血沉積于腦和脊髓表面。經(jīng)典三聯(lián)征包括雙側(cè)感音性耳聾、共濟(jì)失調(diào)及脊髓病變,而且T2MRI的特異性征象為腦干、小腦及脊髓表面的低信號(hào)。可導(dǎo)致慢性蛛網(wǎng)膜下腔出血的常見(jiàn)原因包括中樞神經(jīng)系統(tǒng)腫瘤,頭頸部創(chuàng)傷,動(dòng)靜脈畸形等,仍有近三分之一病例的病因不明。如該病被早期發(fā)現(xiàn),可以通過(guò)遏制出血來(lái)源進(jìn)行治療,但該病的自然病程是一種漸進(jìn)性的神經(jīng)系統(tǒng)功能的低下。 結(jié)論： 中樞神經(jīng)系統(tǒng)的SS為少見(jiàn)的綜合征,行MRI檢查,尤其T2WI序列具有重要診斷價(jià)值。
[Abstract]:Objective: to investigate the imaging features of hemosiderosis (superficial siderosis,SS) on the surface of the central nervous system (CNS). Methods: Siemens 3.0T magnetic resonance imaging system (Verio,Siemens Medical Systems,Erlangen, Germany),) was used to examine MRI in patients with more than 2 years history of craniocerebral trauma or surgery. The parameters were as follows: axial T1WI (TI/TR/TE:823/1900/9) T2WI (TR/TE:6000/96) T2-flair (TI/TR/TE:2140/6600/94) T2-flair T2WI (TR/TE:620/20), sagittal T1WII-T2WI and MR cisternography (TR/TE:1500/224). Results: hemosiderin deposition on the surface of central nervous system is a rare disease of nervous system with bilateral sensorineural deafness ataxia and myelopathy. The common cause is the deposition of hemosiderin on the surface of the brain and spinal cord due to chronic subarachnoid hemorrhage, which needs to be diagnosed on the basis of T 2 low signal intensity shown on T2WI images. When MRI changes slightly, May delay the diagnosis of the disease, Therefore, accurate clinical evaluation and correct imaging techniques can maximize the diagnosis of the disease. MRI images show that hemosiderin is deposited in the brain and spinal cord pial membrane on T2WI sequence showing characteristic linear hypotension. In order to avoid irreversible damage to the central nervous system, even small MR signs associated with the disease should not be underestimated. The imaging findings of SS are associated with subarachnoid hemorrhage. SS is a chronic subarachnoid hemorrhage deposited on the surface of the brain and spinal cord. Classic triple signs include bilateral sensorineural deafness, ataxia and spinal cord lesions, and the specific signs of T2MRI are low signal intensity on the surface of the brain stem, cerebellum and spinal cord. The common causes of chronic subarachnoid hemorrhage include central nervous system tumor, head and neck trauma, arteriovenous malformation and so on. If the disease is detected early, it can be treated by curbing the source of bleeding, but the natural course of the disease is a progressive decline in nervous system function. Conclusion: SS in central nervous system is a rare syndrome. MRI examination, especially T2WI sequence, has important diagnostic value.
【學(xué)位授予單位】：山東大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R445.2;R741
本文編號(hào)：2213012
[Abstract]:Objective: to investigate the imaging features of hemosiderosis (superficial siderosis,SS) on the surface of the central nervous system (CNS). Methods: Siemens 3.0T magnetic resonance imaging system (Verio,Siemens Medical Systems,Erlangen, Germany),) was used to examine MRI in patients with more than 2 years history of craniocerebral trauma or surgery. The parameters were as follows: axial T1WI (TI/TR/TE:823/1900/9) T2WI (TR/TE:6000/96) T2-flair (TI/TR/TE:2140/6600/94) T2-flair T2WI (TR/TE:620/20), sagittal T1WII-T2WI and MR cisternography (TR/TE:1500/224). Results: hemosiderin deposition on the surface of central nervous system is a rare disease of nervous system with bilateral sensorineural deafness ataxia and myelopathy. The common cause is the deposition of hemosiderin on the surface of the brain and spinal cord due to chronic subarachnoid hemorrhage, which needs to be diagnosed on the basis of T 2 low signal intensity shown on T2WI images. When MRI changes slightly, May delay the diagnosis of the disease, Therefore, accurate clinical evaluation and correct imaging techniques can maximize the diagnosis of the disease. MRI images show that hemosiderin is deposited in the brain and spinal cord pial membrane on T2WI sequence showing characteristic linear hypotension. In order to avoid irreversible damage to the central nervous system, even small MR signs associated with the disease should not be underestimated. The imaging findings of SS are associated with subarachnoid hemorrhage. SS is a chronic subarachnoid hemorrhage deposited on the surface of the brain and spinal cord. Classic triple signs include bilateral sensorineural deafness, ataxia and spinal cord lesions, and the specific signs of T2MRI are low signal intensity on the surface of the brain stem, cerebellum and spinal cord. The common causes of chronic subarachnoid hemorrhage include central nervous system tumor, head and neck trauma, arteriovenous malformation and so on. If the disease is detected early, it can be treated by curbing the source of bleeding, but the natural course of the disease is a progressive decline in nervous system function. Conclusion: SS in central nervous system is a rare syndrome. MRI examination, especially T2WI sequence, has important diagnostic value.
【學(xué)位授予單位】：山東大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R445.2;R741
【共引文獻(xiàn)】
相關(guān)期刊論文 前5條
1 趙宏偉;龔向陽(yáng);;中樞神經(jīng)系統(tǒng)表面鐵沉積癥研究進(jìn)展[J];國(guó)際神經(jīng)病學(xué)神經(jīng)外科學(xué)雜志;2014年01期
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相關(guān)碩士學(xué)位論文 前2條
1 趙宏偉;基于MRI ESWAN序列研究單次tSAH引起腦表面鐵質(zhì)沉積癥的可能性[D];浙江大學(xué);2013年
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