本文選題：腦機接口 + 經皮穴位電刺激��； 參考：《福建中醫(yī)藥大學》2014年碩士論文

【摘要】：目的：研究基于腦機接口(Brain-Computer Interface, BCI)對手三里、外關進行經皮電刺激(Transcutanclus Electrical Acupoint Stimulation, TEAS)對缺血性中風恢復期患者上肢運動功能的影響及其影響機制。 方法：將15例嚴重上肢運動功能障礙的缺血性中風患者隨機分為BCI組(8例)和對照組(7例),兩組患者均接受常規(guī)的康復治療及藥物治療,此外BCI組患者接受為期8周,每周3次,每次1-1.5小時基于腦機接口對手三里、外關進行經皮電刺激療法；治療組僅對手三里、外關進行經皮電刺激,治療8周,每周3次,每次20分鐘。分別在治療前后對兩組患者的中醫(yī)證候療效進行評價；用上肢運動功評定量表(Fugl—Meyer motor assessment, FMA)和上肢動作研究測試(Action Research Arm Test, ARAT)評價其運動功能；用運動想象期間的在線準確率及事件相關去同步事件(Event-Related Desynchronization, ERD)評價其治療前后患者腦電信號的改變。 結果：(1)治療后,兩組患者中醫(yī)證候療效比較無顯著性差異(P0.05)。(2)治療后,兩組患者FMA和ARAT評分均顯著高于治療前(P0.05), BCI組患者FMA和ARAT評分顯著高于對照組(P0.05)。(3)治療后,對照組患者在線準確率較治療前無顯著性差異(P0.05)；治療后,BCI組患者在線準確率顯著高于治療前(P0.05), BCI組患者的在線準確率顯著高于對照組(P0.05)。(4)治療后,BCI組患側中央腦區(qū)的ERD程度顯著強于治療前(P0.05),對照組健側中央腦區(qū)的ERD強度顯著高于治療前(P0.05); BCI組患側中央腦區(qū)的ERD強度顯著高于對照組(P0.05)。 結論：對手三里、外關進行經皮電刺激可改善缺血性中風恢復期患者上肢的運動功能；基于腦機接口的經皮穴位電刺激療法可促進患者主動參與康復治療,其對缺血性中風患者的運動功能改善更為顯著；其康復機理可能與基于腦機接口的經皮穴位電刺激療法可增加患側腦區(qū)的激活,優(yōu)化患者大腦運動功能的重組。
[Abstract]:Objective : To study the influence of brain - computer interface ( BCI ) on the exercise function of upper limb in patients with ischemic stroke and its mechanism by using Transcutanclus Electrical Stimulation ( TEAS ) .

Methods : 15 patients with ischemic stroke with severe upper extremity motor dysfunction were randomly divided into BCI group ( 8 cases ) and control group ( 7 cases ) . Both groups received routine rehabilitation therapy and drug therapy .
The curative effect of TCM syndrome of two groups was evaluated before and after treatment .
The exercise function was evaluated by the Fugl - Meyer motor assessment and the upper limb action research test ( ARAT ) .
To evaluate the changes of EEG signals before and after treatment with the online accuracy rate and event - related Desynchronization in the motion picture .

Results : ( 1 ) After the treatment , there was no significant difference between the two groups ( P0.05 ) . After the treatment , the scores of both Chinese and ARAT in both groups were significantly higher than those in the control group ( P0.05 ) . In the control group , there was no significant difference between the two groups ( P0.05 ) .
After treatment , the online accuracy of the patients in the BCI group was significantly higher than that in the control group ( P0.05 ) .

Conclusion : It can improve the exercise function of the upper limb of patients with ischemic stroke during the recovery period of ischemic stroke .
The percutaneous point electro - stimulation therapy based on the brain - computer interface can promote the active participation of the patient in the rehabilitation therapy , which is more remarkable for the improvement of the exercise function of the ischemic stroke patient ;
The mechanism of rehabilitation may be combined with transcutaneous electrical stimulation therapy based on brain - machine interface , which can increase the activation of the affected - side brain region and optimize the function of brain movement of the patient .
【學位授予單位】：福建中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R743.3

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