尿白蛋白排泄率對腦梗死患者發(fā)病的影響
發(fā)布時間:2018-06-19 20:48
本文選題:尿白蛋白排泄率 + 腦梗死; 參考:《中國現(xiàn)代醫(yī)學(xué)雜志》2017年29期
【摘要】:目的探討尿白蛋白排泄率對腦梗死患者發(fā)病的影響。方法選取2013年2月-2015年7月福建醫(yī)科大學(xué)附屬泉州第一醫(yī)院收治的腦梗死患者450例(腦梗死組)和健康者450例(對照組),比較兩組入組者的尿白蛋白排泄率,對入組者的臨床資料進行多因素Logistic回歸分析。結(jié)果兩組尿白蛋白排泄率比較,差異有統(tǒng)計學(xué)意義(P0.05),腦梗死組患者的尿白蛋白排泄率高于對照組。腦梗死組患者合并高血壓、合并冠狀動脈粥樣硬化性心臟病、合并糖尿病、收縮壓、低密度脂蛋白膽固醇、空腹血糖、尿白蛋白排泄率、吸煙及飲酒率與對照組比較,差異有統(tǒng)計學(xué)意義(P0.05)。合并高血壓、合并冠狀動脈粥樣硬化性心臟病、合并糖尿病、低密度脂蛋白膽固醇、尿白蛋白排泄率是影響腦梗死患者發(fā)病的獨立危險因素(P0.05)。結(jié)論尿白蛋白排泄率是影響腦梗死患者發(fā)病的獨立危險因素,可作為預(yù)測腦梗死發(fā)生風(fēng)險的重要指標之一,臨床上應(yīng)對高危患者進行及時干預(yù)和治療。
[Abstract]:Objective to investigate the effect of urinary albumin excretion rate on the pathogenesis of cerebral infarction. Methods from February 2013 to July 2015, 450 patients with cerebral infarction (cerebral infarction group) and 450 healthy subjects (control group) admitted to Quanzhou first Hospital of Fujian Medical University were selected to compare the urinary albumin excretion rate between the two groups. Multivariate logistic regression analysis was used to analyze the clinical data of the patients. Results the urinary albumin excretion rate of the two groups was significantly higher than that of the control group (P 0.05), and the urinary albumin excretion rate in the cerebral infarction group was higher than that in the control group. Compared with the control group, the patients in the cerebral infarction group were complicated with hypertension, coronary atherosclerotic heart disease, diabetes mellitus, systolic blood pressure, low density lipoprotein cholesterol, fasting blood glucose, urinary albumin excretion rate, smoking and drinking rate. The difference was statistically significant (P 0.05). Hypertension, coronary atherosclerotic heart disease, diabetes mellitus, low density lipoprotein cholesterol and urinary albumin excretion rate are independent risk factors for cerebral infarction patients. Conclusion urinary albumin excretion rate is an independent risk factor for patients with cerebral infarction and can be used as an important index to predict the risk of cerebral infarction.
【作者單位】: 福建醫(yī)科大學(xué)附屬泉州第一醫(yī)院神經(jīng)內(nèi)科;
【分類號】:R743.33
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