本文選題：癲癇認(rèn)知功能障礙美國同 + MCCB　； 參考：《昆明醫(yī)科大學(xué)》2014年碩士論文

【摘要】：目的應(yīng)用鄒義壯2006年引進(jìn)美國MCCB凸理測量學(xué)量表而形成的認(rèn)知功能量表中文版初步探討成年癲癇患者的認(rèn)知功能障礙特點(diǎn)、影響成年癲癇患者認(rèn)知障礙的各相關(guān)因素。 方法依據(jù)設(shè)定的癲癇病例組和健康對(duì)照組的納入和排除標(biāo)準(zhǔn),選取2013年06月至2014年02月在昆明醫(yī)科大學(xué)第一附屬醫(yī)院神經(jīng)內(nèi)科就診的癲癇患者,共45例為癲癇病例組,以與癲癇病例組年齡、性別、教育程度相匹配的患者家屬、陪護(hù)人員、醫(yī)務(wù)人員等健康人群50例為健康對(duì)照組。應(yīng)用由鄒義壯2006年引進(jìn)美國MCCB心理測量學(xué)量表而形成的認(rèn)知功能量表中文版從信息處理速度、注意／警覺性、記憶、執(zhí)行能力、語言能力等方面評(píng)估研究對(duì)象的認(rèn)知情況。計(jì)算出每位研究對(duì)象的量表總分,每個(gè)子項(xiàng)目的得分。采用SPSS for windows18.0統(tǒng)計(jì)軟件分析所得數(shù)據(jù)。通過兩樣本均數(shù)比較的t檢驗(yàn)分析癲癇病例組和健康對(duì)照組的得分的差異是否有統(tǒng)計(jì)學(xué)意義而得出癲癇患者是否存在認(rèn)知功能的障礙。按照起病年齡、受教育程度、發(fā)作頻率、發(fā)作類型、病程持續(xù)時(shí)間、用藥種類和發(fā)作持續(xù)時(shí)間等將癲癇病例組進(jìn)行分組評(píng)估,通過組間Spearman相關(guān)分析來分析這些因素與量表總分及每個(gè)子項(xiàng)目間的相關(guān)性。 結(jié)果1、兩樣本t檢驗(yàn)顯示,癲癇患者與健康對(duì)照組認(rèn)知功能比較,在信息處理速度(P0.05)、注意／警覺性(P0.05)、記憶(工作記憶、言語記憶P0.05,視覺記憶P0.01)、執(zhí)行能力(P0.05)、語言能力(P0.01)方面均有統(tǒng)計(jì)學(xué)意義。2、Spearman相關(guān)分析顯示癲癇患者認(rèn)知功能測試總評(píng)分與文化程度、起病年齡和疾病嚴(yán)重程度之間,相關(guān)系數(shù)有顯著統(tǒng)計(jì)學(xué)意義(P0.01),而與用藥數(shù)量、發(fā)作時(shí)間、頻率、類型之間存在統(tǒng)計(jì)學(xué)意義(P0.05) 結(jié)論1、癲癇患者存在認(rèn)知功能障礙,并普遍表現(xiàn)在信息處理速度、注意/警覺性、記憶、執(zhí)行能力、語言能力方面。2、癲癇患者的認(rèn)知功能障礙程度與文化程度、起病年齡、病程長短、發(fā)作頻率、發(fā)作持續(xù)時(shí)間、發(fā)作類型及用藥數(shù)量有關(guān)。
[Abstract]:Objective to explore the characteristics of cognitive dysfunction in adult epileptic patients using the Chinese version of MCCB Convexity Measurement scale introduced by Zou Yizhuang in 2006. Methods according to the established criteria for the inclusion and exclusion of epilepsy cases group and healthy control group, From June 2013 to February 2014, 45 epileptic patients in the Department of Neurology, the first affiliated Hospital of Kunming Medical University, were selected. 50 cases of healthy people such as medical personnel were taken as healthy control group. The Chinese version of the MCCB psychometric scale introduced by Zou in 2006 was used to evaluate the cognitive status of the subjects in terms of information processing speed, attention / alertness, memory, executive ability, language ability, and so on. The total score of each research object and the score of each subitem were calculated. The data were analyzed by SPSS for windows18.0 software. The difference of scores between epileptic patients and healthy control group was analyzed by t test of comparing the mean of two samples, and whether there was cognitive impairment in epileptic patients was obtained. According to the onset age, education level, attack frequency, attack type, duration of course, drug use and duration of seizure, the epileptic patients were divided into two groups. Spearman correlation analysis was used to analyze the correlation between these factors and the total score of the scale and each sub-item. Results 1. The t test of two samples showed that the cognitive function of epileptic patients was compared with that of healthy controls. At the rate of information processing, P0.05, attention / alertness, P0.05, memory (working memory, The correlation analysis of speech memory, visual memory, executive ability and language ability showed that the total score of cognitive function test was correlated with the education level, the age of onset and the severity of the disease in epileptic patients. The correlation coefficient was statistically significant (P 0.01), but there was significant difference between the number of drugs, attack time, frequency and type. Conclusion 1. There are cognitive dysfunction in epileptic patients, which is generally manifested in information processing speed, attention / alertness. Memory, executive ability and language ability. The degree of cognitive dysfunction in epileptic patients was related to their education, onset age, duration, frequency, duration, type and quantity of medication.
【學(xué)位授予單位】：昆明醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R742.1

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 盧穎瑜;王鵬;李永鴻;巫碧佳;黃秉文;;成年癲癇患者認(rèn)知功能與生活質(zhì)量的研究觀察[J];當(dāng)代醫(yī)學(xué);2013年17期

2 虞培敏;郭起浩;丁玎;周燕;洪震;;癲沲患者認(rèn)知功能特點(diǎn)的研究[J];中國臨床神經(jīng)科學(xué);2006年05期

3 呂高萍;蘇涵;蔣麗麗;;24h動(dòng)態(tài)腦電圖在老年癲癇診斷中的應(yīng)用[J];吉林醫(yī)學(xué);2012年33期

4 陳鶯;李焰生;王智櫻;;急性腦卒中患者的失語亞型與經(jīng)典腦皮質(zhì)語言中樞的關(guān)系[J];上海醫(yī)學(xué);2010年09期

5 羅鳳云;;老年性癲癇的病因分析與臨床特點(diǎn)[J];實(shí)用心腦肺血管病雜志;2011年11期

6 張人玲;李坤成;張海琴;;發(fā)作間期SPECT對(duì)難治性顳葉癲癇的診斷價(jià)值[J];醫(yī)學(xué)影像學(xué)雜志;2012年01期

7 王學(xué)峰;;癲癇定義及分類:歷史、內(nèi)涵、新觀念[J];中華全科醫(yī)師雜志;2007年12期

8 于鳳穎;王穎;;癲癇患者認(rèn)知功能障礙相關(guān)因素分析[J];中國老年學(xué)雜志;2012年10期

9 趙麗秀;;老年糖尿病繼發(fā)癲癇16例分析[J];中國民康醫(yī)學(xué);2011年14期

10 汪凱;田仰華;;神經(jīng)心理學(xué)在行為神經(jīng)病學(xué)中的重要作用[J];中國神經(jīng)精神疾病雜志;2009年10期

，

本文編號(hào)：2004435