發(fā)布時(shí)間：2018-05-25 09:47

  本文選題：彌散張量成像 + 多模態(tài)影像��； 參考：《蚌埠醫(yī)學(xué)院》2017年碩士論文

【摘要】：目的:應(yīng)用功能神經(jīng)導(dǎo)航實(shí)現(xiàn)T1WI、DTI、DTT等多種模態(tài)的融合,用以指導(dǎo)涉及主要功能纖維束的顱內(nèi)病變手術(shù),以期達(dá)到最小化的神經(jīng)功能損傷以及最大化病灶切除的效果。方法:觀察2013年12月-2016年8月,我院神經(jīng)外科25例腦功能區(qū)腫瘤在多模態(tài)神經(jīng)導(dǎo)航輔助下的手術(shù)情況,隨機(jī)抽取同期在傳統(tǒng)神經(jīng)導(dǎo)航輔助下手術(shù)切除的25例病例作為對照組。比較并分析兩組手術(shù)在腫瘤全切率、術(shù)后致殘率、平均住院時(shí)間、預(yù)后等方面的差異性。結(jié)果:研究組平均手術(shù)時(shí)間5.6±1.3 h,對照組平均5.4±1.5 h,差異無統(tǒng)計(jì)學(xué)意義(P0.05)。研究組平均住院時(shí)間16.35±4.29 d,對照組19.57±6.15 d,研究組平均住院時(shí)間明顯短于對照組(P0.05)。研究組全切除19例(76%),次全切除4例,部分切除2例;對照組全切除12例(48%),次全切除9例,部分切除4例;研究組腫瘤全切除率高于對照組(P0.05)。研究組出現(xiàn)并發(fā)癥4例(16%),對照組13例(52%),兩組差異顯著。研究組平均KPS評分為89.12±17.35分,對照組為73.56±18.21分,差異有統(tǒng)計(jì)學(xué)意義(p0.05)。結(jié)論:融合DTT等多種模態(tài)的功能神經(jīng)導(dǎo)航,可以顯著提高鄰近錐體束及視放射等功能纖維束腦腫瘤的全切除率,有效降低患者術(shù)后致殘率,臨床療效顯著。
[Abstract]:Objective: to use functional neuronavigation to realize the fusion of T1WIN DTI DTT and other modes to guide the operation of intracranial lesions involving the main functional fibrous bundles in order to minimize the injury of nerve function and maximize the effect of lesion resection. Methods: from December 2013 to August 2016, 25 patients with brain functional area tumors in our hospital were treated with multimodal neuronavigation and 25 patients were randomly selected as control group. The difference of total tumor resection rate, postoperative disability rate, average hospitalization time and prognosis between the two groups were compared and analyzed. Results: the mean operative time was 5.6 鹵1.3 hours in the study group and 5.4 鹵1.5 hours in the control group. There was no significant difference between the two groups (P 0.05). The average hospitalization time was 16.35 鹵4.29 days in the study group and 19.57 鹵6.15 days in the control group. The average hospitalization time in the study group was significantly shorter than that in the control group (P 0.05). There were 19 cases of total resection, 4 cases of subtotal resection, 2 cases of partial resection in the study group, 12 cases of total resection, 9 cases of subtotal resection and 4 cases of partial resection in the control group. The total resection rate of tumor in the study group was higher than that in the control group (P 0.05). Complications were found in 4 cases in the study group and in 13 cases in the control group. The average KPS score was 89.12 鹵17.35 in the study group and 73.56 鹵18.21 in the control group. The difference was statistically significant (P 0.05). Conclusion: the fusion of DTT and other modes of functional neuronavigation can significantly improve the rate of total resection of brain tumors of the adjacent pyramidal tract and visual radiation, and effectively reduce the rate of postoperative disability, and the clinical efficacy is remarkable.
【學(xué)位授予單位】：蚌埠醫(yī)學(xué)院
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R739.4

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