發(fā)布時(shí)間：2018-05-14 18:39

  本文選題：動(dòng)脈粥樣硬化 + 大腦中動(dòng)脈　； 參考：《揚(yáng)州大學(xué)》2014年碩士論文

【摘要】：目的： 應(yīng)用3.0T高分辨磁共振成像(high resolution magnetic resonance imaging, HRMRI)分析紋狀體內(nèi)囊梗死發(fā)病機(jī)制及病因,并探討其與斑塊的關(guān)系。 方法： 對(duì)2013年1月至2013年12月期間在我院神經(jīng)內(nèi)科住院的新發(fā)紋狀體內(nèi)囊梗死患者19例,基底節(jié)區(qū)急性腔隙性腦梗死患者21例分別進(jìn)行了3.0T高分辨磁共振成像(high resolution magnetic resonance imaging, HRMRI),對(duì)其病灶同側(cè)大腦中動(dòng)脈局部進(jìn)行HRMRI,分析2組局部大腦中動(dòng)脈病變的發(fā)生率,同時(shí),根據(jù)局部成像結(jié)果將SCI患者再分為局部有斑塊組和局部無斑塊組,比較分析了兩組間血壓、血糖、血脂水平,入院時(shí)和入院后NIHSS評(píng)分、運(yùn)動(dòng)障礙加重的發(fā)生率。 結(jié)果： SCI患者同側(cè)大腦中動(dòng)脈局部病變的發(fā)生率(36.84%,7/19)明顯高于同側(cè)LI患者(23.81%,2/21)；有SCI大腦中動(dòng)脈局部斑塊的患者較無局部動(dòng)脈病灶患者初始臨床癥狀重(NIHSS6.57±2.3vs3.77±1.96, P0.05),且前者早期臨床運(yùn)動(dòng)癥狀進(jìn)展的發(fā)生率高于后者(71.43%vs16.67%,P0.029),兩組之間比較血液LDL-C患者有顯著性差異。 結(jié)論： 1、HRMRI可清晰顯示大腦中動(dòng)脈的管壁結(jié)構(gòu),并能發(fā)現(xiàn)管腔內(nèi)附著的斑塊。 2、SCI中斑塊組較非斑塊組初始臨床癥狀重,且臨床癥狀更易進(jìn)展加重,其中LDL-C水平可作為SCI斑塊形成的預(yù)測(cè)指標(biāo)。
[Abstract]:Objective: The pathogenesis and etiology of striatal intracapsular infarction were analyzed by high resolution magnetic resonance imaging, HRMRI) 3.0T high resolution magnetic resonance imaging, and the relationship between high resolution MRI and plaque was discussed. Methods: From January 2013 to December 2013, 19 patients with newly diagnosed Intrastriatal Infarction were hospitalized in the Department of Neurology in our hospital. 21 patients with acute lacunar infarction in basal ganglia region were treated with 3.0T high resolution magnetic resonance imaging and high resolution magnetic resonance imaging, MRI respectively. HRMRI was performed on the ipsilateral middle cerebral artery to analyze the incidence of local middle cerebral artery lesions in two groups. According to the local imaging results, the patients with SCI were divided into local plaque group and local plaque group. The blood pressure, blood glucose, blood lipid level, NIHSS score on admission and after admission, and the incidence of aggravation of motor disorder were compared between the two groups. Results: The incidence of local lesions of the ipsilateral middle cerebral artery in SCI patients was significantly higher than that in ipsilateral Li patients (36.847 / 19), and the initial clinical symptoms of patients with local plaques of middle cerebral artery with SCI were significantly higher than those without local arterial lesions (NIHSS 6.57 鹵2.3vs3.77 鹵1.96, P0.05). The incidence of dynamic symptom progression was higher than that of the latter group (71.43 vs 16.67) (P 0.029). There was a significant difference between the two groups in blood LDL-C patients. Conclusion: 1HRMRI can clearly display the wall structure of the middle cerebral artery and the plaques attached in the lumen. (2) the initial clinical symptoms in the plaque group were more severe than those in the non-plaque group, and the clinical symptoms were more easily aggravated, and the LDL-C level could be used as a predictor of the formation of SCI plaque.
【學(xué)位授予單位】：揚(yáng)州大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R445.2;R743.3

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