本文選題：腦炎 + 病毒性　； 參考：《重慶醫(yī)學(xué)》2017年14期

【摘要】：目的探討自身免疫性腦炎不同類型的臨床表現(xiàn)、輔助檢查、確診方法。方法回顧性分析在河北大學(xué)附屬醫(yī)院就診的6例自身免疫性腦炎患者的臨床表現(xiàn)、檢查結(jié)果、治療及預(yù)后。結(jié)果 6例患者其中2例為抗N-甲基-D-天冬氨酸(NMDA)受體抗體腦炎,2例富亮氨酸膠質(zhì)瘤失活1蛋白(LGIl)抗體腦炎,2例抗γ-氨基丁酸B型(GABAB)受體抗體腦炎。患者均表現(xiàn)不同程度的癲癇、精神癥狀以及運動障礙等,臨床表現(xiàn)形式多樣,確診依靠血液及腦脊液檢查相關(guān)抗體陽性。早期進(jìn)行免疫抑制療法聯(lián)合激素治療,未合并腫瘤患者預(yù)后較好,合并腫瘤患者預(yù)后不良。結(jié)論對于以癲癇或者精神異常起病的患者,應(yīng)考慮到自身免疫性腦炎的可能,及時行腰部穿刺進(jìn)行腦脊液檢查。
[Abstract]:Objective to investigate the clinical manifestations, auxiliary examination and diagnostic methods of autoimmune encephalitis in 6 cases of autoimmune encephalitis in the Affiliated Hospital of Hebei University. The results, treatment and prognosis of 6 cases of autoimmune encephalitis were reviewed. Of the 6 patients, 2 cases were anti N- -D- aspartic acid (NMDA) receptor antibody brain Inflammation, 2 cases of leucine glioma inactivating 1 protein (LGIl) antibody encephalitis and 2 cases of anti gamma aminobutyric acid B (GABAB) receptor antibody encephalitis. The patients showed various levels of epilepsy, mental symptoms and dyskinesia, and the clinical manifestations were varied. The diagnosis depended on the blood and cerebrospinal fluid examination related antibody positive. Early immunosuppressive therapy was carried out. The prognosis of the patients without tumor is better, and the prognosis of the patients with the tumor is poor. Conclusion for the patients with epilepsy or abnormal mental illness, the possibility of autoimmune encephalitis should be considered and the cerebrospinal fluid examination should be carried out in time by the lumbar puncture.

【作者單位】： 河北大學(xué)醫(yī)學(xué)院;河北大學(xué)附屬醫(yī)院神經(jīng)內(nèi)科;
【分類號】：R744.5

【相似文獻(xiàn)】

相關(guān)期刊論文 前4條

1 張彥;;免疫球蛋白聯(lián)合激素治療小兒格林-巴利綜合征療效觀察[J];中華實用診斷與治療雜志;2010年03期

2 張其相;暢慧君;;高壓氧聯(lián)合激素治療急性一氧化碳中毒后遲發(fā)性腦病的臨床研究[J];現(xiàn)代醫(yī)藥衛(wèi)生;2008年08期

3 何遠(yuǎn)知;;影響兒童眼肌型重癥肌無力療效的相關(guān)因素分析[J];安徽醫(yī)學(xué);2014年09期

4 ;[J];;年期

，

本文編號：1811768