發(fā)布時間：2018-04-23 11:12

  本文選題：舞蹈癥 + 非酮癥高血糖��； 參考：《中國神經(jīng)精神疾病雜志》2017年08期

【摘要】：目的探討非酮癥性高血糖合并舞蹈癥患者的臨床、影像學(xué)特點及隨訪結(jié)果。方法對6例非酮癥性高血糖合并舞蹈癥患者的臨床資料、出院后隨訪結(jié)果進行回顧性分析。結(jié)果患者的平均起病年齡為(65.83±13.93)歲,其中女性患者5例,男性1例;急性-亞急性病程,患者表現(xiàn)為單側(cè)(n=5例)或雙側(cè)肢體(n=1)舞蹈樣動作,面部肌肉均有受累(n=6)。入院時靜脈血糖平均值為:(9.21±5.15)mmol/L;所有患者的糖化血紅蛋白顯著升高:(14.1%±3.5%)。所有患者的MRI均提示基底節(jié)區(qū)T1序列高信號病灶,均累及殼核,可同時合并豆?fàn)詈�、尾狀核受�?3例患者磁敏感成像(SWI)序列發(fā)現(xiàn),對應(yīng)的基底節(jié)區(qū)病灶為低信號病灶。2例患者發(fā)現(xiàn)大腦中動脈重度狹窄。5例患者平均隨訪(16.2±7.2)個月,3例患者死亡。結(jié)論顱腦MRI示基底節(jié)區(qū)T1加權(quán)序列高信號病灶是C-H-BG主要特點;患者可合并對應(yīng)的SWI序列的低信號病灶。
[Abstract]:Objective to investigate the clinical, imaging features and follow-up results of non-ketotic hyperglycemia with chorea. Methods the clinical data of 6 patients with nonketotic hyperglycemia complicated with chorea were retrospectively analyzed. Results the average onset age of the patients was 65.83 鹵13.93 years old, of which 5 cases were female, 1 case was male, and 5 cases were acute subacute disease. The mean venous blood glucose at admission was 9. 21 鹵5. 15 mmol / L; the glycosylated hemoglobin of all patients was significantly increased by 14. 1% 鹵3. 5%. The MRI of all patients showed that the basal ganglia T1 sequence was hyperintense and involved the putamen nucleus, which could be combined with lentiform nucleus and magnetic sensitive imaging (MRI) sequence in 3 patients with caudate nucleus involvement. The corresponding basal ganglia lesions were low signal lesions in 2 patients with severe stenosis of the middle cerebral artery. The mean follow-up of 5 patients was 16.2 鹵7.2 months and 3 patients died. Conclusion brain MRI is the main feature of C-H-BG with high signal intensity on T1 weighted sequence of basal ganglia, and patients can be combined with low signal lesions of corresponding SWI sequence.
【作者單位】： 東莞市人民醫(yī)院神經(jīng)內(nèi)科;
【分類號】：R587.2;R742.2

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