本文選題：復(fù)元醒腦 + 活血通腑��； 參考：《成都中醫(yī)藥大學(xué)》2014年博士論文

【摘要】：目的：評(píng)價(jià)元?dú)馓澨撠灤┰诩毙阅X出血的整個(gè)過程,比較復(fù)元醒腦法與活血通腑在急性腦出血的臨床療效。 方法：在全國(guó)5家醫(yī)療單位開展復(fù)元醒腦與活血通腑治療急性腦出血臨床對(duì)照研究,治療組采用復(fù)元醒腦法方案,即在常規(guī)西醫(yī)治療基礎(chǔ)上,加用具有益氣活血、泄熱熄風(fēng)功效的中風(fēng)醒腦方(紅參、大黃、川芎、三七)；對(duì)照組采用活血通腑法方案,采用常規(guī)西醫(yī)治療基礎(chǔ)上加大黃、川芎、三七。觀察患者治療前后神經(jīng)功能缺損積分、血腫吸收率、中醫(yī)癥狀體征嚴(yán)重程度積分、電解質(zhì)紊亂肺部感染、便秘等指標(biāo)的改變,評(píng)價(jià)治療14±2天、21±3天患者的情況。 結(jié)果： 1.神經(jīng)功能缺損改變：治療14±2天、21±3天治療神經(jīng)功能缺損積分改善情況優(yōu)于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)； 2.血腫吸收率：14±2天時(shí)治療組血腫吸收率優(yōu)于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)； 3.中醫(yī)癥狀體征改變：治療14±2天、21±3天治療組中醫(yī)癥狀體征積分改善情況優(yōu)于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)； 4.治療組肺部感染改善情況優(yōu)于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.01) 5.治療組電解質(zhì)紊亂改善情況優(yōu)于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.01) 6.便秘情況：治療組便秘改善情況優(yōu)于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05) 結(jié)論： 1.復(fù)元醒腦法治療方案能改善急性腦出血患者神經(jīng)功能缺損情況,在治療21±3天時(shí)改善患者的神經(jīng)功能缺損程度優(yōu)于活血通腑法治療方案； 2.復(fù)元醒腦法治療方案能促進(jìn)出急性腦出血患者血腫吸收,在14±2天時(shí)優(yōu)于活血通腑法治療方案； 3.復(fù)元醒腦法治療方案在改善癥狀體征的嚴(yán)重程度積分及對(duì)生活的影響程度上優(yōu)于活血通腑法治療方案。 4.復(fù)元醒腦法治療方案在改善肺部感染情況上優(yōu)于活血通腑法治療方案。 5.復(fù)元醒腦法治療方案在改善電解質(zhì)紊亂情況上優(yōu)于活血通腑法治療方案。 6.復(fù)元醒腦法治療方案在改善便秘情況優(yōu)于活血通腑法治療方案。
[Abstract]:Objective: to evaluate the clinical efficacy of Fuyuan Xingnao method and Huoxue Tongfu in acute intracerebral hemorrhage. Methods: a clinical controlled study on the treatment of acute cerebral hemorrhage was carried out in 5 medical units in China. In the treatment group, the treatment group was treated with Fuyuan Xingnao method, that is, on the basis of routine western medicine treatment, the treatment group was treated with a combination of nourishing qi and activating blood circulation. Xingnao Fang of apoplexy (Radix Ginseng, Rhubarb, Chuanxiong, Panax Notoginseng, Radix et Rhizoma et Rhizoma Chuanxiong, Panax notoginseng). The changes of neurological deficit score, hematoma absorption rate, severity score of symptoms and signs of TCM, electrolyte disturbance pulmonary infection and constipation were observed before and after treatment, and the results of 14 鹵2 days and 21 鹵3 days of treatment were evaluated. Results: 1. The improvement of neural function defect score in 14 鹵2 days and 21 鹵3 days of treatment was better than that in the control group, and the difference was statistically significant (P 0.05). 2. The hematoma absorption rate in the treatment group was better than that in the control group on the day of 14 鹵2 days, and the difference was statistically significant (P 0.05). 3. The changes of TCM symptoms and signs: the improvement of TCM symptom and sign score in the treatment group was better than that in the control group on 14 鹵2 days and 21 鹵3 days, and the difference was statistically significant (P 0.05); 4. The improvement of pulmonary infection in the treatment group was better than that in the control group (P 0.01). 5. The improvement of electrolyte disturbance in the treatment group was better than that in the control group (P 0.01). 6. Constipation: the improvement of constipation in the treatment group was better than that in the control group (P 0.05). Conclusion: 1. Fuyuan Xingnao method can improve the neurological function defect in patients with acute intracerebral hemorrhage, and it is better than Huoxue Tongfu method in improving the degree of neurological function defect in 21 鹵3 days. 2. Fuyuan Xingnao method can promote hematoma absorption in patients with acute intracerebral hemorrhage, and it is better than Huoxue Tongfu method in 14 鹵2 days. 3. Fuyuan Xingnao method was superior to Huoxue Tongfu method in improving the severity score of symptoms and signs and its influence on life. 4. Fuyuan Xingnao method is superior to Huoxue Tongfu method in improving pulmonary infection. 5. Fuyuan Xingnao method is superior to Huoxue Tongfu method in improving electrolyte disorder. 6. Fuyuan Xingnao method is better than Huoxue Tongfu method in improving constipation.
【學(xué)位授予單位】：成都中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：博士
【學(xué)位授予年份】：2014
【分類號(hào)】：R743.3

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