顯微手術(shù)聯(lián)合伽馬刀對竇旁腦膜瘤的治療效果研究及安全性評價
發(fā)布時間:2018-04-18 01:37
本文選題:顯微手術(shù) + 伽馬刀; 參考:《臨床醫(yī)學(xué)研究與實踐》2016年21期
【摘要】:目的探討顯微手術(shù)聯(lián)合伽馬刀對竇旁腦膜瘤的治療效果及安全性。方法選取2010年2月至2011年2月我院收治的50例竇旁腦膜瘤患者,按照手術(shù)治療方式的不同分為兩組,對照組(20例)采用常規(guī)手術(shù)治療,觀察組(30例)采用顯微手術(shù)聯(lián)合伽馬刀治療。比較兩組患者治療后的腫瘤切除率、神經(jīng)功能評分、并發(fā)癥發(fā)生率、復(fù)發(fā)率及預(yù)后良好率。結(jié)果觀察組全部行腦膜瘤Simpson Ⅱ~Ⅲ級切除,對照組全部行腦膜瘤Simpson Ⅰ級切除。兩組患者治療前神經(jīng)功能評分差異無統(tǒng)計學(xué)意義(P0.05),治療后兩組患者神經(jīng)功能評分均顯著降低,且觀察組神經(jīng)功能評分顯著低對照組,差異具有統(tǒng)計學(xué)意義(P0.05)。觀察組的并發(fā)癥發(fā)生率及復(fù)發(fā)率均明顯低于對照組,差異有統(tǒng)計學(xué)意義(P0.05)。兩組患者5年隨訪結(jié)果顯示,觀察組患者的預(yù)后良好率顯著優(yōu)于對照組,差異具有統(tǒng)計學(xué)意義(P0.05)。結(jié)論采用顯微手術(shù)聯(lián)合伽馬刀治療竇旁腦膜瘤可有效提高腫瘤全切率,減少神經(jīng)功能的損傷和并發(fā)癥的發(fā)生,顯著提高患者術(shù)后的生存率和生存質(zhì)量。
[Abstract]:Objective to evaluate the efficacy and safety of microsurgery combined with gamma knife in the treatment of paranasal meningioma.Methods from February 2010 to February 2011, 50 patients with periantral meningioma were divided into two groups according to the different surgical treatment methods. The control group (n = 20) was treated with routine operation.The observation group (n = 30) was treated with microsurgery combined with gamma knife.The tumor resection rate, neurological function score, complication rate, recurrence rate and good prognosis were compared between the two groups.Results all the patients in the observation group were treated with Simpson 鈪,
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