腦腫瘤患者術(shù)后顱內(nèi)感染病原學特點及危險因素分析
發(fā)布時間:2018-04-02 06:37
本文選題:腦腫瘤 切入點:顱內(nèi)感染 出處:《中華醫(yī)院感染學雜志》2017年21期
【摘要】:目的探討腦腫瘤患者術(shù)后顱內(nèi)感染病原學特點及危險因素。方法選取醫(yī)院2013年5月-2016年5月收治的腦腫瘤手術(shù)患者920例,統(tǒng)計感染患者病原菌分布,分析顱內(nèi)感染的危險因素。結(jié)果腦腫瘤術(shù)后患者顱內(nèi)感染48例,感染率為5.22%,感染患者共分離出病原菌46株,其中革蘭陽性菌14株,占30.44%,革蘭陰性菌31株,占67.39%,真菌1株,占2.17%;革蘭陰性菌對阿米卡星、慶大霉素、亞胺培南、美羅培南耐藥率較高,革蘭陽性菌對萬古霉素、紅霉素、利福平耐藥率較高;腦脊液漏、手術(shù)持續(xù)時間≥3h、后顱窩手術(shù)為腦腫瘤術(shù)后顱內(nèi)感染的相關(guān)因素;腦脊液漏、手術(shù)持續(xù)時間≥3h和后顱窩手術(shù)為獨立危險因素。結(jié)論革蘭陰性菌為腦腫瘤患者術(shù)后顱內(nèi)感染主要病原菌,顱內(nèi)感染危險因素較多,應針對病原菌特點及危險因素,采取相應的措施,降低顱內(nèi)感染。
[Abstract]:Objective to investigate the etiological characteristics and risk factors of intracranial infection in patients with brain tumor after operation.Methods 920 patients with brain tumor were selected from May 2013 to May 2016. The distribution of pathogenic bacteria in infected patients was analyzed and the risk factors of intracranial infection were analyzed.Results there were 48 patients with intracranial infection after operation of brain tumor, the infection rate was 5.22. A total of 46 pathogenic bacteria were isolated from the infected patients, of which 14 were Gram-positive bacteria (30.44%), 31 Gram-negative bacteria (67.39%) and 1 fungus (2.17%).The resistance rate of gentamicin, imipenem and meropenem was higher, the resistance rate of gram-positive bacteria to vancomycin, erythromycin and rifampicin was higher; cerebrospinal fluid leakage,The operative duration 鈮,
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